| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.273858 |
| DST | dystonin | 0.222334 |
| CAPRIN2 | caprin family member 2 | 0.114745 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0762556 |
| RPS6 | ribosomal protein S6 | 0.075589 |
| RPS19 | ribosomal protein S19 | 0.0702359 |
| RPS12 | ribosomal protein S12 | 0.0682873 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0585397 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0582391 |
| MT1X | metallothionein 1X | 0.0574808 |
| RPL26 | ribosomal protein L26 | 0.0563918 |
| TMSB4X | thymosin beta 4, X-linked | 0.0563872 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0552726 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0551725 |
| RPL19 | ribosomal protein L19 | 0.0514926 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0509952 |
| AHNAK | AHNAK nucleoprotein | 0.0508776 |
| RUNX1 | runt-related transcription factor 1 | 0.0497187 |
| TXNIP | thioredoxin interacting protein | 0.0488406 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0484735 |
| TPM3 | tropomyosin 3 | 0.0479231 |
| MT1E | metallothionein 1E | 0.0477695 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0476237 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0475436 |
| YBX1 | Y box binding protein 1 | 0.0465017 |
| RPS2 | ribosomal protein S2 | 0.0456788 |
| PRELID2 | PRELI domain containing 2 | 0.0456378 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0451993 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0447213 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0446738 |
| B2M | beta-2-microglobulin | 0.0440699 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0436381 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0435247 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.042642 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0423191 |
| TP63 | tumor protein p63 | 0.0419514 |
| RPL36 | ribosomal protein L36 | 0.0413509 |
| VCL | vinculin | 0.0409031 |
| HLA-B | major histocompatibility complex, class I, B | 0.0395994 |
| FMNL2 | formin-like 2 | 0.0393622 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0388117 |
| TPI1 | triosephosphate isomerase 1 | 0.0378121 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0366714 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.036267 |
| UBC | ubiquitin C | 0.0361598 |
| PTMA | prothymosin, alpha | 0.0352689 |
| RPS8 | ribosomal protein S8 | 0.0347936 |
| CADM2 | cell adhesion molecule 2 | 0.034267 |
| RPL35 | ribosomal protein L35 | 0.0339742 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0336676 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0333243 |
| RPL23 | ribosomal protein L23 | 0.0329908 |
| DPH6 | diphthamine biosynthesis 6 | 0.0327133 |
| SON | SON DNA binding protein | 0.0325582 |
| GOLGB1 | golgin B1 | 0.0324358 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0323618 |
| FNIP1 | folliculin interacting protein 1 | 0.0318471 |
| RPL34 | ribosomal protein L34 | 0.0318449 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.031842 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0317933 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0317834 |
| SLK | STE20-like kinase | 0.0317361 |
| RPL12 | ribosomal protein L12 | 0.0314837 |
| H1-0 | H1.0 linker histone | 0.0312472 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0312252 |
| SDC4 | syndecan 4 | 0.0308343 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0307742 |
| RPL18 | ribosomal protein L18 | 0.0306167 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0304254 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0302532 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0296759 |
| F2R | coagulation factor II (thrombin) receptor | 0.029554 |
| RAD51B | RAD51 paralog B | 0.0295206 |
| ANKRD12 | ankyrin repeat domain 12 | 0.028978 |
| VEGFC | vascular endothelial growth factor C | 0.0289284 |
| RPS21 | ribosomal protein S21 | 0.0288879 |
| PDE10A | phosphodiesterase 10A | 0.0285469 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0280752 |
| RPL3 | ribosomal protein L3 | 0.0277352 |
| GOLGA4 | golgin A4 | 0.0273358 |
| SMYD3 | SET and MYND domain containing 3 | 0.0270285 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268717 |
| SFTPA2 | surfactant protein A2 | 0.0265935 |
| MKI67 | marker of proliferation Ki-67 | 0.0264355 |
| EXOC4 | exocyst complex component 4 | 0.0263247 |
| RPL37 | ribosomal protein L37 | 0.0261507 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0260106 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0258221 |
| CEP290 | centrosomal protein 290kDa | 0.0254342 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0254142 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0253831 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0253743 |
| SVIL | supervillin | 0.0251125 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0250387 |
| ASPH | aspartate beta-hydroxylase | 0.0249942 |
| CDK6 | cyclin-dependent kinase 6 | 0.0244656 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.024452 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0242429 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0241856 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0240548 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.141867 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110744 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0994966 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0716799 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0668513 |
| FTL | ferritin, light polypeptide | -0.0630286 |
| TXNRD1 | thioredoxin reductase 1 | -0.0630211 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0598258 |
| VIM | vimentin | -0.0555878 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0549452 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0507398 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0469988 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0455796 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0443924 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0435271 |
| RPL35A | ribosomal protein L35a | -0.0409554 |
| ACTG1 | actin gamma 1 | -0.0397014 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0390203 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.034293 |
| ANXA1 | annexin A1 | -0.0332779 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0315508 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0313738 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0305068 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0301934 |
| WDR45B | WD repeat domain 45B | -0.0282205 |
| HMGA1 | high mobility group AT-hook 1 | -0.0279814 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0275044 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0273055 |
| RAI1 | retinoic acid induced 1 | -0.0269154 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.026521 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.026452 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0261939 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0257736 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0251424 |
| WASF2 | WAS protein family, member 2 | -0.0250592 |
| EGR1 | early growth response 1 | -0.0249968 |
| SPAG9 | sperm associated antigen 9 | -0.0245587 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0243249 |
| CANX | calnexin | -0.0238994 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0236961 |
| FOSL1 | FOS-like antigen 1 | -0.0234859 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0232964 |
| RPL39 | ribosomal protein L39 | -0.0230217 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0228612 |
| RPL5 | ribosomal protein L5 | -0.0227 |
| UPP1 | uridine phosphorylase 1 | -0.0226104 |
| USP34 | ubiquitin specific peptidase 34 | -0.0222514 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.022128 |
| KIAA1958 | KIAA1958 | -0.0210658 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0210396 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0209764 |
| RPS24 | ribosomal protein S24 | -0.020955 |
| TMEM123 | transmembrane protein 123 | -0.020587 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0205137 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0200076 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.019517 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0194729 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0193102 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0192331 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0192132 |
| ANXA2 | annexin A2 | -0.0191472 |
| RYBP | RING1 and YY1 binding protein | -0.0191248 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0190881 |
| S100A10 | S100 calcium binding protein A10 | -0.0187817 |
| NAV2 | neuron navigator 2 | -0.0187081 |
| RPLP1 | ribosomal protein, large, P1 | -0.018699 |
| LDHA | lactate dehydrogenase A | -0.0186365 |
| EREG | epiregulin | -0.018617 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0185806 |
| RLF | rearranged L-myc fusion | -0.0184437 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0183718 |
| RPS25 | ribosomal protein S25 | -0.0181809 |
| RPS20 | ribosomal protein S20 | -0.018007 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0176226 |
| CENPF | centromere protein F, 350/400kDa | -0.0175077 |
| USP36 | ubiquitin specific peptidase 36 | -0.0174893 |
| TUBA1C | tubulin, alpha 1c | -0.0174725 |
| CD44 | CD44 molecule (Indian blood group) | -0.0174563 |
| NUP58 | nucleoporin 58 | -0.0173046 |
| RPLP0 | ribosomal protein, large, P0 | -0.0172038 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.016949 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0167749 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0167066 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0166558 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0164981 |
| RPS13 | ribosomal protein S13 | -0.0164647 |
| MIS18BP1 | MIS18 binding protein 1 | -0.016239 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0159182 |
| RPS16 | ribosomal protein S16 | -0.0157194 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0157119 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0156799 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0156555 |
| RPS29 | ribosomal protein S29 | -0.0155163 |
| ARF4 | ADP-ribosylation factor 4 | -0.0155113 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0154502 |
| USP3 | ubiquitin specific peptidase 3 | -0.0154487 |
| TFG | TRK-fused gene | -0.0154148 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0151624 |
| RPL9 | ribosomal protein L9 | -0.0149252 |
| RPL27A | ribosomal protein L27a | -0.0149007 |
