| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.104805 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.101673 |
| MT2A | metallothionein 2A | 0.101044 |
| LAMC2 | laminin, gamma 2 | 0.100285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0976336 |
| SLTM | SAFB-like, transcription modulator | 0.0895295 |
| LMO7 | LIM domain 7 | 0.0851499 |
| MCL1 | myeloid cell leukemia 1 | 0.0779276 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0762474 |
| AREG | amphiregulin | 0.0758602 |
| LAMA4 | laminin, alpha 4 | 0.0754854 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0706591 |
| STC1 | stanniocalcin 1 | 0.0651232 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0609202 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0604821 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0579719 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0519648 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.051764 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.051342 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0458235 |
| AHNAK | AHNAK nucleoprotein | 0.0440975 |
| HSPA8 | heat shock 70kDa protein 8 | 0.042703 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0397629 |
| SMYD3 | SET and MYND domain containing 3 | 0.0396092 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0392462 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0389396 |
| OSMR | oncostatin M receptor | 0.038805 |
| MT1X | metallothionein 1X | 0.0387609 |
| TPM3 | tropomyosin 3 | 0.0383196 |
| RPS6 | ribosomal protein S6 | 0.0379249 |
| LAMB3 | laminin, beta 3 | 0.0353509 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.035141 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0346115 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0345628 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0343613 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0336979 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0316418 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0306633 |
| DOCK1 | dedicator of cytokinesis 1 | 0.029344 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0285095 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0281108 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0261881 |
| YBX3 | Y box binding protein 3 | 0.0261811 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0261468 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.02585 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0257741 |
| BPTF | bromodomain PHD finger transcription factor | 0.0256913 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0255856 |
| RPS12 | ribosomal protein S12 | 0.0255003 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0253412 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0252969 |
| SYAP1 | synapse associated protein 1 | 0.0251077 |
| ANKRD11 | ankyrin repeat domain 11 | 0.024893 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.024309 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0236854 |
| DSPP | dentin sialophosphoprotein | 0.0233916 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0233691 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0231042 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0230834 |
| BMP6 | bone morphogenetic protein 6 | 0.0226919 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0225562 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0225484 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0222254 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0220589 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0219052 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0218711 |
| SIK3 | SIK family kinase 3 | 0.0216844 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0216592 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.021533 |
| UBC | ubiquitin C | 0.0214895 |
| PLAUR | plasminogen activator, urokinase receptor | 0.021428 |
| OXSR1 | oxidative stress responsive 1 | 0.0214004 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.021361 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0213286 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0213142 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0212089 |
| DSG2 | desmoglein 2 | 0.0210072 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0206734 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0206122 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0205551 |
| MSN | moesin | 0.0205414 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0204945 |
| RPL19 | ribosomal protein L19 | 0.0204391 |
| RPL34 | ribosomal protein L34 | 0.0202359 |
| ACTN1 | actinin, alpha 1 | 0.0201002 |
| RPS19 | ribosomal protein S19 | 0.0198257 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0195357 |
| VEGFC | vascular endothelial growth factor C | 0.0193224 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0191839 |
| HMGA2 | high mobility group AT-hook 2 | 0.0190256 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0189502 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0188684 |
| KRT18 | keratin 18, type I | 0.0187689 |
| ATP11A | ATPase, class VI, type 11A | 0.0187039 |
| EGR1 | early growth response 1 | 0.0186401 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0184113 |
| VCL | vinculin | 0.0183209 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.018263 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0182518 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0182313 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.419992 |
| EGFR | epidermal growth factor receptor | -0.314399 |
| TXNRD1 | thioredoxin reductase 1 | -0.123216 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0963563 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0900549 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0809643 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0579277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0542885 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0504978 |
| TMEM165 | transmembrane protein 165 | -0.0498512 |
| CST3 | cystatin C | -0.0487371 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.046947 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0461219 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0453825 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0449043 |
| USP34 | ubiquitin specific peptidase 34 | -0.0430153 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0425868 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0419921 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0418702 |
| FTL | ferritin, light polypeptide | -0.0408841 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0406989 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0403862 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0396838 |
| WASF2 | WAS protein family, member 2 | -0.0391297 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0375841 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0366683 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0363063 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0359989 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0359211 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0352768 |
| PTMA | prothymosin, alpha | -0.0349659 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0340854 |
| LDHA | lactate dehydrogenase A | -0.0325501 |
| RPS25 | ribosomal protein S25 | -0.031302 |
| FNDC3B | fibronectin type III domain containing 3B | -0.030961 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0308318 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0299428 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0299314 |
| GPC6 | glypican 6 | -0.0297351 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0289519 |
| AGR2 | anterior gradient 2 | -0.028887 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0282866 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0282568 |
| TFG | TRK-fused gene | -0.0280372 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0278152 |
| PKM | pyruvate kinase, muscle | -0.0278051 |
| CANX | calnexin | -0.0267324 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.026505 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0263186 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260053 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.0256071 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0251373 |
| HDLBP | high density lipoprotein binding protein | -0.0249607 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0249406 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0247596 |
| CCND1 | cyclin D1 | -0.0246889 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0245963 |
| WDR45B | WD repeat domain 45B | -0.0245326 |
| FAM13A | family with sequence similarity 13, member A | -0.0244109 |
| SPAG9 | sperm associated antigen 9 | -0.0243715 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0243485 |
| MYOF | myoferlin | -0.0238643 |
| PGK1 | phosphoglycerate kinase 1 | -0.0237048 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0234937 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0233518 |
| RPL35A | ribosomal protein L35a | -0.0227524 |
| NGLY1 | N-glycanase 1 | -0.0227206 |
| SUCO | SUN domain containing ossification factor | -0.0225459 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0225178 |
| FNIP1 | folliculin interacting protein 1 | -0.0222978 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0219723 |
| RYBP | RING1 and YY1 binding protein | -0.0219497 |
| SQSTM1 | sequestosome 1 | -0.021909 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0216463 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0215762 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0214477 |
| TNS3 | tensin 3 | -0.0213661 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0213419 |
| TPD52 | tumor protein D52 | -0.0213012 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0212379 |
| SEPTIN2 | septin 2 | -0.0209787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.020921 |
| SRP54 | signal recognition particle 54kDa | -0.020811 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0206047 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0205299 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0203882 |
| ACTG1 | actin gamma 1 | -0.0203428 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0202542 |
| KRT7 | keratin 7, type II | -0.0201952 |
| SLMAP | sarcolemma associated protein | -0.02017 |
| NUP58 | nucleoporin 58 | -0.0201508 |
| SEC24D | SEC24 family member D | -0.0200863 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0199505 |
| PCBP2 | poly(rC) binding protein 2 | -0.0198446 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0198172 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0196367 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0195869 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0188482 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0186033 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0185269 |
