| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.311211 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.160827 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.113373 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0823932 |
| HMGA2 | high mobility group AT-hook 2 | 0.0817364 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0781718 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0715495 |
| NDRG1 | N-myc downstream regulated 1 | 0.0700476 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0670555 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0667129 |
| VEGFA | vascular endothelial growth factor A | 0.0657448 |
| ASPH | aspartate beta-hydroxylase | 0.0626431 |
| EFNA5 | ephrin-A5 | 0.0625645 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0610344 |
| DST | dystonin | 0.0547533 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0539963 |
| NAV2 | neuron navigator 2 | 0.0530951 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0503692 |
| IFI44L | interferon-induced protein 44-like | 0.0498543 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0476939 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0459298 |
| MTSS1 | metastasis suppressor 1 | 0.0453526 |
| GLCCI1 | glucocorticoid induced 1 | 0.044537 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0443371 |
| NRP1 | neuropilin 1 | 0.0430202 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0411226 |
| ZNF638 | zinc finger protein 638 | 0.0407201 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0389701 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0387006 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0386394 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.037505 |
| VEGFC | vascular endothelial growth factor C | 0.0374009 |
| MEF2A | myocyte enhancer factor 2A | 0.036025 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0356366 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0349126 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0348773 |
| PRELID2 | PRELI domain containing 2 | 0.0347993 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0347207 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0344029 |
| STK38L | serine/threonine kinase 38 like | 0.0333739 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0330992 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0329816 |
| PTK2 | protein tyrosine kinase 2 | 0.0316863 |
| SIK3 | SIK family kinase 3 | 0.0316329 |
| SFTPA2 | surfactant protein A2 | 0.0311572 |
| FAM219A | family with sequence similarity 219, member A | 0.0308622 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0308057 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0305779 |
| CDH13 | cadherin 13 | 0.0300164 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0292434 |
| FAM13A | family with sequence similarity 13, member A | 0.0289225 |
| FLNB | filamin B, beta | 0.0283757 |
| SMAD3 | SMAD family member 3 | 0.0276579 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0276159 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.027416 |
| ANGPTL4 | angiopoietin-like 4 | 0.027345 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0272995 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0272113 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0270987 |
| PRSS3 | protease, serine, 3 | 0.0268804 |
| MT2A | metallothionein 2A | 0.0267891 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0266713 |
| ANO6 | anoctamin 6 | 0.0265972 |
| WLS | wntless Wnt ligand secretion mediator | 0.0264421 |
| ADD3 | adducin 3 (gamma) | 0.0263778 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.026222 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0260733 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0256424 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0255553 |
| PYGL | phosphorylase, glycogen, liver | 0.0251071 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0247338 |
| AHNAK | AHNAK nucleoprotein | 0.0246919 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.024402 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0243093 |
| CLMP | CXADR-like membrane protein | 0.024223 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0241141 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0239734 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0239168 |
| TPM3 | tropomyosin 3 | 0.0238501 |
| PHF21A | PHD finger protein 21A | 0.0234272 |
| IL1B | interleukin 1, beta | 0.0233613 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230945 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0229724 |
| RUNX1 | runt-related transcription factor 1 | 0.0229712 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0229563 |
| ATXN1 | ataxin 1 | 0.0227244 |
| ANXA10 | annexin A10 | 0.0226344 |
| SVIL | supervillin | 0.0226057 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0223916 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0223802 |
| HELZ | helicase with zinc finger | 0.0222277 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0221424 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0220159 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0219846 |
| RPL3 | ribosomal protein L3 | 0.0219703 |
| DTNA | dystrobrevin, alpha | 0.0219302 |
| CEP250 | centrosomal protein 250kDa | 0.0217619 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0217313 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0214152 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0212338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.150924 |
| VIM | vimentin | -0.124491 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109587 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0986314 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.089087 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0823596 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0793743 |
| OSMR | oncostatin M receptor | -0.0780239 |
| TMSB10 | thymosin beta 10 | -0.0771221 |
| LOX | lysyl oxidase | -0.0720303 |
| RPL35A | ribosomal protein L35a | -0.0683797 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0639016 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0624347 |
| RBM39 | RNA binding motif protein 39 | -0.0600815 |
| PTMA | prothymosin, alpha | -0.0595573 |
| FTL | ferritin, light polypeptide | -0.0584758 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0582748 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0582627 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0547042 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0537669 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.051945 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0512419 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.051122 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0489364 |
| GOLGA4 | golgin A4 | -0.0457449 |
| KYNU | kynureninase | -0.0455668 |
| VCL | vinculin | -0.0438564 |
| IER3 | immediate early response 3 | -0.0431559 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0425896 |
| GPC6 | glypican 6 | -0.0424592 |
| TNNC1 | troponin C type 1 (slow) | -0.0420426 |
| LMAN1 | lectin, mannose-binding, 1 | -0.041279 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0403683 |
| RPL31 | ribosomal protein L31 | -0.0400741 |
| EGR1 | early growth response 1 | -0.0398757 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0388577 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0381628 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0381163 |
| CALU | calumenin | -0.0369787 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0354321 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.034909 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0348733 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0347925 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345923 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0342427 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0340246 |
| IL1R1 | interleukin 1 receptor, type I | -0.0339439 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0339315 |
| RPS25 | ribosomal protein S25 | -0.0328513 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0325454 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0324179 |
| MORF4L2 | mortality factor 4 like 2 | -0.0320499 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0320402 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316801 |
| FN1 | fibronectin 1 | -0.0316482 |
| VMP1 | vacuole membrane protein 1 | -0.0313543 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0292792 |
| RPS24 | ribosomal protein S24 | -0.0290896 |
| HDLBP | high density lipoprotein binding protein | -0.0289756 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0288687 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0288678 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0287897 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0286869 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0285939 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0284695 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0284586 |
| HM13 | histocompatibility (minor) 13 | -0.0281529 |
| RPS29 | ribosomal protein S29 | -0.0276067 |
| USP34 | ubiquitin specific peptidase 34 | -0.0274056 |
| ARF4 | ADP-ribosylation factor 4 | -0.0273414 |
| SBF2 | SET binding factor 2 | -0.0273281 |
| NTN4 | netrin 4 | -0.027184 |
| WDR45B | WD repeat domain 45B | -0.0270586 |
| VRK2 | vaccinia related kinase 2 | -0.0270559 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0267751 |
| RPS13 | ribosomal protein S13 | -0.0267265 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0266202 |
| NLK | nemo-like kinase | -0.0253545 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.024957 |
| ETV6 | ets variant 6 | -0.0248699 |
| NF1 | neurofibromin 1 | -0.0247915 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0247395 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0245897 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0244576 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0244549 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0241095 |
| BPTF | bromodomain PHD finger transcription factor | -0.0239586 |
| ARF1 | ADP-ribosylation factor 1 | -0.0238675 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0237644 |
| YME1L1 | YME1-like 1 ATPase | -0.0235746 |
| KPNB1 | karyopherin (importin) beta 1 | -0.023549 |
| SEC24D | SEC24 family member D | -0.0234882 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0232928 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231789 |
| TMEM263 | transmembrane protein 263 | -0.0231649 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0231557 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0229526 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0228425 |
| USP15 | ubiquitin specific peptidase 15 | -0.0228362 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0227844 |
