| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.221319 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.200482 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.180315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.152172 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.113475 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0871425 |
| PYGL | phosphorylase, glycogen, liver | 0.0722535 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.068668 |
| STC1 | stanniocalcin 1 | 0.0644526 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0640753 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0634885 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.062657 |
| EGFR | epidermal growth factor receptor | 0.0591536 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0589679 |
| EGR1 | early growth response 1 | 0.057551 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0571812 |
| CMIP | c-Maf inducing protein | 0.0539622 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0533586 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0528903 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0522575 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0511369 |
| GOLGA4 | golgin A4 | 0.051038 |
| MCL1 | myeloid cell leukemia 1 | 0.0509774 |
| RPS6 | ribosomal protein S6 | 0.0508295 |
| OSMR | oncostatin M receptor | 0.0505742 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0498116 |
| VCL | vinculin | 0.0483921 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0482778 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0482528 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.047104 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0459823 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.045367 |
| PCNX4 | pecanex 4 | 0.0452026 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0443309 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.043773 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0430615 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.04288 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0426909 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0417382 |
| KYNU | kynureninase | 0.0414906 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0411773 |
| WAC | WW domain containing adaptor with coiled-coil | 0.040949 |
| S100A10 | S100 calcium binding protein A10 | 0.039071 |
| KIF5B | kinesin family member 5B | 0.0386995 |
| SNX14 | sorting nexin 14 | 0.0372234 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0369509 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0364741 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0361997 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0361344 |
| NUMB | numb homolog (Drosophila) | 0.0360448 |
| FBXO11 | F-box protein 11 | 0.0360313 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0359064 |
| GOLGB1 | golgin B1 | 0.0342291 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.033915 |
| MT1X | metallothionein 1X | 0.0335883 |
| IGF2 | insulin-like growth factor 2 | 0.0335262 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0334567 |
| FLNB | filamin B, beta | 0.0333039 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0332142 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0332109 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0329419 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0325683 |
| NDRG1 | N-myc downstream regulated 1 | 0.0322261 |
| BRD2 | bromodomain containing 2 | 0.0314747 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0311239 |
| AHNAK | AHNAK nucleoprotein | 0.0310637 |
| MKI67 | marker of proliferation Ki-67 | 0.0310097 |
| RPL35A | ribosomal protein L35a | 0.0309812 |
| GLG1 | golgi glycoprotein 1 | 0.0309171 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0308409 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0306443 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0305847 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.030309 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.030271 |
| LAMC2 | laminin, gamma 2 | 0.030066 |
| EHBP1 | EH domain binding protein 1 | 0.0296841 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0296384 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0296082 |
| CDK13 | cyclin-dependent kinase 13 | 0.0295973 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0294932 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0294229 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0294224 |
| LDHA | lactate dehydrogenase A | 0.0288993 |
| STK17A | serine/threonine kinase 17a | 0.0288805 |
| TOP1 | topoisomerase (DNA) I | 0.0288554 |
| CDCP1 | CUB domain containing protein 1 | 0.0283721 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0280952 |
| CFDP1 | craniofacial development protein 1 | 0.0280069 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0278618 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0278601 |
| HLA-A | major histocompatibility complex, class I, A | 0.0276532 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0275006 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0271986 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0270285 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0267791 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0267215 |
| RBM39 | RNA binding motif protein 39 | 0.0265037 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0262846 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0262364 |
| PRKCA | protein kinase C, alpha | 0.0261847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | -0.177521 |
| PM20D1 | peptidase M20 domain containing 1 | -0.157617 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.136261 |
| TXNRD1 | thioredoxin reductase 1 | -0.133676 |
| FTL | ferritin, light polypeptide | -0.118211 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.102808 |
| PTMA | prothymosin, alpha | -0.0921294 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0730629 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.069622 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0677672 |
| RPL23 | ribosomal protein L23 | -0.0672455 |
| RPS27A | ribosomal protein S27a | -0.0657089 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0633537 |
| FGB | fibrinogen beta chain | -0.0617902 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0576837 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0496022 |
| UBC | ubiquitin C | -0.0459621 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0415645 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0384706 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.037622 |
| PCBP2 | poly(rC) binding protein 2 | -0.0369242 |
| USP3 | ubiquitin specific peptidase 3 | -0.0369206 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0364463 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0357383 |
| PRR16 | proline rich 16 | -0.0356228 |
| NEGR1 | neuronal growth regulator 1 | -0.0345639 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0340654 |
| POTEF | POTE ankyrin domain family, member F | -0.0333208 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0329627 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0323 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0318538 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0318424 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0318135 |
| ACTG1 | actin gamma 1 | -0.031714 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.031066 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0303429 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0295882 |
| FAM107B | family with sequence similarity 107, member B | -0.0284754 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0283761 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0279471 |
| RTN4 | reticulon 4 | -0.027729 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0276845 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0276198 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0276088 |
| RPS12 | ribosomal protein S12 | -0.0272586 |
| ECT2 | epithelial cell transforming 2 | -0.0270993 |
| FGG | fibrinogen gamma chain | -0.027041 |
| RPS3 | ribosomal protein S3 | -0.0268555 |
| THBS1 | thrombospondin 1 | -0.0267922 |
| AHR | aryl hydrocarbon receptor | -0.0266395 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0265777 |
| TUBA1B | tubulin, alpha 1b | -0.0264638 |
| WWOX | WW domain containing oxidoreductase | -0.0263831 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0263413 |
| EFNA5 | ephrin-A5 | -0.0256829 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0252729 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -0.025034 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0249914 |
| BICC1 | BicC family RNA binding protein 1 | -0.0248354 |
| FAM168A | family with sequence similarity 168, member A | -0.0242755 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0239059 |
| RAD51B | RAD51 paralog B | -0.0232022 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0231973 |
| TUBB | tubulin, beta class I | -0.0228896 |
| VSIG2 | V-set and immunoglobulin domain containing 2 | -0.0227726 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0227428 |
| FLNA | filamin A, alpha | -0.0222493 |
| PDE8A | phosphodiesterase 8A | -0.0220808 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0217275 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0216281 |
| WDR43 | WD repeat domain 43 | -0.0215078 |
| MORF4L1 | mortality factor 4 like 1 | -0.0215066 |
| SQSTM1 | sequestosome 1 | -0.0212325 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0212073 |
| UPP1 | uridine phosphorylase 1 | -0.0211868 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0211704 |
| YBX3 | Y box binding protein 3 | -0.021082 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0210434 |
| TAGLN2 | transgelin 2 | -0.0209993 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0206878 |
| YBX1 | Y box binding protein 1 | -0.0206502 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.0206412 |
| CHN1 | chimerin 1 | -0.0205561 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0203442 |
| HMGB1 | high mobility group box 1 | -0.0202138 |
| AREG | amphiregulin | -0.0200538 |
| ENO1 | enolase 1, (alpha) | -0.0200474 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0200405 |
| EXOC4 | exocyst complex component 4 | -0.0200125 |
| DCLK2 | doublecortin-like kinase 2 | -0.0199012 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0197119 |
| FSTL5 | follistatin-like 5 | -0.0193901 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0193322 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0193017 |
| WTAP | Wilms tumor 1 associated protein | -0.0192613 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0192455 |
| RBM25 | RNA binding motif protein 25 | -0.019211 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0191603 |
| CALR | calreticulin | -0.0191523 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0189708 |
