| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0953906 |
| TXNRD1 | thioredoxin reductase 1 | 0.0887898 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0810025 |
| ASPH | aspartate beta-hydroxylase | 0.071054 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0700057 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0693559 |
| EFNA5 | ephrin-A5 | 0.0692542 |
| OGA | O-GlcNAcase | 0.0689742 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0628289 |
| KYNU | kynureninase | 0.059148 |
| DENND5B | DENN/MADD domain containing 5B | 0.0589078 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0578013 |
| ATXN1 | ataxin 1 | 0.0570397 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0556581 |
| USP34 | ubiquitin specific peptidase 34 | 0.0548754 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0532334 |
| PRKCA | protein kinase C, alpha | 0.0530579 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0525444 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0524171 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0517802 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0496293 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0478815 |
| RPS12 | ribosomal protein S12 | 0.0472352 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0468111 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.045709 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0456324 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0434189 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0426159 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0420265 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0414245 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0409453 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0403156 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0402837 |
| FOXJ3 | forkhead box J3 | 0.0401502 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0399078 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0398306 |
| TJP1 | tight junction protein 1 | 0.0395443 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0394251 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0394219 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0387945 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0385471 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0381529 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.037897 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0377092 |
| VIM | vimentin | 0.0373568 |
| TMSB10 | thymosin beta 10 | 0.0372166 |
| TMSB4X | thymosin beta 4, X-linked | 0.0369811 |
| NCKAP1 | NCK-associated protein 1 | 0.0368836 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0368264 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0367196 |
| SH3D19 | SH3 domain containing 19 | 0.0367041 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0364637 |
| SBF2 | SET binding factor 2 | 0.0350527 |
| DST | dystonin | 0.0347939 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0345493 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0344681 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.034345 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0337935 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0337035 |
| GRAMD1B | GRAM domain containing 1B | 0.0336242 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0323707 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0321086 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0317507 |
| RPS3 | ribosomal protein S3 | 0.0316391 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0315178 |
| YY1AP1 | YY1 associated protein 1 | 0.0313288 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0313241 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0313181 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0311442 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0309254 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0309152 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0307982 |
| CENPF | centromere protein F, 350/400kDa | 0.0307368 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0307105 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.030676 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0306692 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0306061 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0306046 |
| FBXO32 | F-box protein 32 | 0.0304796 |
| SYNRG | synergin, gamma | 0.030422 |
| CCDC47 | coiled-coil domain containing 47 | 0.0304006 |
| TUSC3 | tumor suppressor candidate 3 | 0.0300969 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0300555 |
| THOC2 | THO complex 2 | 0.0296919 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0296687 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0296174 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0293465 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0292344 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0292292 |
| RBM39 | RNA binding motif protein 39 | 0.029115 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0290611 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0288628 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0288198 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.028753 |
| EXOC6B | exocyst complex component 6B | 0.0287494 |
| CERT1 | ceramide transporter 1 | 0.0286347 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0286161 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0284776 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0284145 |
| RBM25 | RNA binding motif protein 25 | 0.028225 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.17785 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.16272 |
| GRB10 | growth factor receptor-bound protein 10 | -0.161035 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.149294 |
| MYO1E | myosin IE | -0.135429 |
| ANXA2 | annexin A2 | -0.115889 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.110293 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103297 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0979103 |
| CMIP | c-Maf inducing protein | -0.0952723 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0915591 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.088664 |
| LAMB3 | laminin, beta 3 | -0.0875426 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0750373 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0749431 |
| MUC16 | mucin 16, cell surface associated | -0.0742479 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0737141 |
| KRT17 | keratin 17, type I | -0.0714996 |
| LAMC2 | laminin, gamma 2 | -0.0693639 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.068325 |
| LMO7 | LIM domain 7 | -0.0673551 |
| SGMS2 | sphingomyelin synthase 2 | -0.0659256 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0622703 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0608074 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0603589 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0562099 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0544023 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0543262 |
| SVIL | supervillin | -0.0537045 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0515026 |
| PATJ | PATJ crumbs cell polarity complex component | -0.051292 |
| GLUL | glutamate-ammonia ligase | -0.0503032 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0501352 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0501229 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0499565 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0493853 |
| RBM47 | RNA binding motif protein 47 | -0.0471707 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0466442 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0464285 |
| YME1L1 | YME1-like 1 ATPase | -0.0448734 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | -0.0447707 |
| JUP | junction plakoglobin | -0.0442851 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0440585 |
| MEF2A | myocyte enhancer factor 2A | -0.0438145 |
| TC2N | tandem C2 domains, nuclear | -0.0435607 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0435472 |
| VCL | vinculin | -0.0434453 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0427956 |
| GPC6 | glypican 6 | -0.0426617 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.042388 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0413481 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0411955 |
| FRMD6 | FERM domain containing 6 | -0.0411056 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0404998 |
| SETX | senataxin | -0.0396006 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0392432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0388065 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0387345 |
| RESF1 | retroelement silencing factor 1 | -0.0386867 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0386624 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0386503 |
| TJP2 | tight junction protein 2 | -0.038371 |
| FOXO1 | forkhead box O1 | -0.0375811 |
| RREB1 | ras responsive element binding protein 1 | -0.0374149 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0371099 |
| OXR1 | oxidation resistance 1 | -0.0368389 |
| ZNF217 | zinc finger protein 217 | -0.0366504 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0364501 |
| MRTFA | myocardin related transcription factor A | -0.0363868 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0361733 |
| ACTG1 | actin gamma 1 | -0.0361672 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0361479 |
| WNT9A | wingless-type MMTV integration site family, member 9A | -0.0360185 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.035957 |
| WDR26 | WD repeat domain 26 | -0.0357513 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0355187 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0353516 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0353394 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0351322 |
| ETV3 | ets variant 3 | -0.0348404 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0346358 |
| SUCO | SUN domain containing ossification factor | -0.0336305 |
| STEAP4 | STEAP family member 4 | -0.0336135 |
| PALLD | palladin, cytoskeletal associated protein | -0.0334463 |
| IRF6 | interferon regulatory factor 6 | -0.0332432 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0331872 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0329587 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.03293 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0326812 |
| ANKRD36C | ankyrin repeat domain 36C | -0.032465 |
| EGR1 | early growth response 1 | -0.0321965 |
| PRELID2 | PRELI domain containing 2 | -0.0321899 |
| TMEM165 | transmembrane protein 165 | -0.0320515 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0318197 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0317825 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0316022 |
| ETV6 | ets variant 6 | -0.031492 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0314714 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0314296 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0313549 |
