| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.228826 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.111139 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0893834 |
| LAMB3 | laminin, beta 3 | 0.0814456 |
| EFNA5 | ephrin-A5 | 0.0744591 |
| ERBIN | erbb2 interacting protein | 0.0729857 |
| AHNAK | AHNAK nucleoprotein | 0.0693496 |
| DSPP | dentin sialophosphoprotein | 0.0675342 |
| GOLGB1 | golgin B1 | 0.0633953 |
| MAP1B | microtubule-associated protein 1B | 0.0622268 |
| VEGFA | vascular endothelial growth factor A | 0.0621855 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0602423 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0598148 |
| FBXO32 | F-box protein 32 | 0.0542388 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0524308 |
| LMO7 | LIM domain 7 | 0.0511807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0495597 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0489406 |
| RAI14 | retinoic acid induced 14 | 0.0481344 |
| LAMC2 | laminin, gamma 2 | 0.0473467 |
| TPM3 | tropomyosin 3 | 0.043803 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0432455 |
| TMF1 | TATA element modulatory factor 1 | 0.0428831 |
| DST | dystonin | 0.0425884 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0421279 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0418433 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0414555 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0410462 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0409013 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0408978 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0403421 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0401621 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0395937 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0388656 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0372352 |
| MX1 | MX dynamin-like GTPase 1 | 0.0371722 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0371258 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0365688 |
| TXNIP | thioredoxin interacting protein | 0.0364601 |
| VGLL3 | vestigial-like family member 3 | 0.0364559 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0363615 |
| RPS6 | ribosomal protein S6 | 0.0362707 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0351792 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0351342 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0342895 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0340803 |
| MYO5B | myosin VB | 0.0329353 |
| RASAL2 | RAS protein activator like 2 | 0.0328654 |
| FNIP1 | folliculin interacting protein 1 | 0.0325309 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0320838 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0314194 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0313127 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.03081 |
| EGFR | epidermal growth factor receptor | 0.0292017 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0291271 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0291231 |
| SVIL | supervillin | 0.0290997 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0287597 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.028745 |
| MX2 | MX dynamin-like GTPase 2 | 0.0286222 |
| GOLM1 | golgi membrane protein 1 | 0.0284777 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0283826 |
| MSN | moesin | 0.0273317 |
| ATXN1 | ataxin 1 | 0.027284 |
| ETV6 | ets variant 6 | 0.0272417 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0272203 |
| DTNA | dystrobrevin, alpha | 0.0272138 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0264639 |
| RAD51B | RAD51 paralog B | 0.0263692 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0263215 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0260182 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0258563 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0255878 |
| BCL2L1 | BCL2-like 1 | 0.0254356 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.025389 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0253673 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0252483 |
| MYO6 | myosin VI | 0.024788 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0246944 |
| HLA-A | major histocompatibility complex, class I, A | 0.0246118 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0245203 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0244729 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0244662 |
| CTSS | cathepsin S | 0.0243166 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.024298 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0242858 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0241986 |
| VCL | vinculin | 0.0237674 |
| DSG2 | desmoglein 2 | 0.0236981 |
| ANO6 | anoctamin 6 | 0.0235963 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0234937 |
| ANKRD12 | ankyrin repeat domain 12 | 0.023361 |
| HDAC9 | histone deacetylase 9 | 0.0233051 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0229698 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0229178 |
| JUP | junction plakoglobin | 0.0228217 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.022624 |
| FTL | ferritin, light polypeptide | 0.0225902 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0224156 |
| RIGI | RNA sensor RIG-I | 0.0220538 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.241845 |
| FN1 | fibronectin 1 | -0.222992 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.192852 |
| PTMA | prothymosin, alpha | -0.170505 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.135326 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.121267 |
| NDRG1 | N-myc downstream regulated 1 | -0.0833459 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0791191 |
| S100A6 | S100 calcium binding protein A6 | -0.0723816 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0702543 |
| TFG | TRK-fused gene | -0.0694722 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0661596 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0660812 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0574159 |
| ACTG1 | actin gamma 1 | -0.057316 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0566387 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0566174 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0544799 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0518756 |
| RPS24 | ribosomal protein S24 | -0.0476036 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0440465 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0436591 |
| ZNF292 | zinc finger protein 292 | -0.0425241 |
| RYBP | RING1 and YY1 binding protein | -0.042429 |
| MSMO1 | methylsterol monooxygenase 1 | -0.041526 |
| RPLP1 | ribosomal protein, large, P1 | -0.0410197 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0400319 |
| PGK1 | phosphoglycerate kinase 1 | -0.0392641 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0379679 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0378138 |
| HMGA1 | high mobility group AT-hook 1 | -0.0365633 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0364718 |
| RPL35A | ribosomal protein L35a | -0.0353728 |
| RLF | rearranged L-myc fusion | -0.0352654 |
| HMGB2 | high mobility group box 2 | -0.0350781 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0347424 |
| CLINT1 | clathrin interactor 1 | -0.0346632 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0342165 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0333474 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0332496 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0331515 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0330769 |
| TMEM123 | transmembrane protein 123 | -0.0329401 |
| RPLP0 | ribosomal protein, large, P0 | -0.0326805 |
| SQSTM1 | sequestosome 1 | -0.0325595 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0321361 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0320147 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.031912 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0316996 |
| FAM162A | family with sequence similarity 162, member A | -0.0313188 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0311783 |
| RPL27A | ribosomal protein L27a | -0.0311767 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0306432 |
| RPL38 | ribosomal protein L38 | -0.030496 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0303935 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0302912 |
| ANLN | anillin, actin binding protein | -0.0297408 |
| CCNI | cyclin I | -0.0294772 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0291782 |
| USP3 | ubiquitin specific peptidase 3 | -0.0291587 |
| RHEB | Ras homolog enriched in brain | -0.0288945 |
| RNF145 | ring finger protein 145 | -0.0288813 |
| NUP58 | nucleoporin 58 | -0.0288561 |
| PAPOLA | poly(A) polymerase alpha | -0.0284446 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0283663 |
| RPL7 | ribosomal protein L7 | -0.0282103 |
| CHMP2B | charged multivesicular body protein 2B | -0.0279764 |
| MATR3 | matrin 3 | -0.0279587 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0279582 |
| ASPH | aspartate beta-hydroxylase | -0.0277425 |
| TFRC | transferrin receptor | -0.0277334 |
| TKT | transketolase | -0.0275859 |
| CANX | calnexin | -0.0275556 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0275406 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0275078 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0274421 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0274308 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0273395 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0271972 |
| RPS25 | ribosomal protein S25 | -0.026729 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0267064 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.026536 |
| CALR | calreticulin | -0.0264436 |
| CPNE8 | copine VIII | -0.0262211 |
| PEG10 | paternally expressed 10 | -0.0261745 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0259998 |
| RHOA | ras homolog family member A | -0.0259861 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.025824 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0249631 |
| CDC73 | cell division cycle 73 | -0.0248721 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0248329 |
| QKI | QKI, KH domain containing, RNA binding | -0.0248276 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0247769 |
| ARF1 | ADP-ribosylation factor 1 | -0.0247568 |
| SEPTIN7 | septin 7 | -0.0246118 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0245508 |
| DSTN | destrin (actin depolymerizing factor) | -0.0244942 |
| SPAG9 | sperm associated antigen 9 | -0.0244655 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0244488 |
| NCKAP1 | NCK-associated protein 1 | -0.0243667 |
