| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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196 genes differentially expressed following the Pasireotide (acetate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.184224 |
| EGFR | epidermal growth factor receptor | 0.133958 |
| PDE10A | phosphodiesterase 10A | 0.12982 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.104333 |
| PTK2 | protein tyrosine kinase 2 | 0.0990296 |
| EHBP1 | EH domain binding protein 1 | 0.095455 |
| SEPTIN9 | septin 9 | 0.095094 |
| ASPH | aspartate beta-hydroxylase | 0.0837042 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0818498 |
| LAMC2 | laminin, gamma 2 | 0.0805154 |
| SLTM | SAFB-like, transcription modulator | 0.0780332 |
| IGF2 | insulin-like growth factor 2 | 0.0753833 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0715593 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0698775 |
| SMAD3 | SMAD family member 3 | 0.0690359 |
| SBF2 | SET binding factor 2 | 0.0688279 |
| MYO1E | myosin IE | 0.0687663 |
| PLCB4 | phospholipase C, beta 4 | 0.0672399 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.066133 |
| NAV2 | neuron navigator 2 | 0.0655154 |
| DSPP | dentin sialophosphoprotein | 0.0651975 |
| RAB1A | RAB1A, member RAS oncogene family | 0.064562 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635523 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0634289 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0624289 |
| MYO10 | myosin X | 0.0612231 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0609613 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0600833 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0581448 |
| RAD51B | RAD51 paralog B | 0.0565666 |
| PRKCA | protein kinase C, alpha | 0.0533668 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0523452 |
| MT2A | metallothionein 2A | 0.0492699 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0489431 |
| SRPK2 | SRSF protein kinase 2 | 0.0486743 |
| HMGA2 | high mobility group AT-hook 2 | 0.0470901 |
| OSMR | oncostatin M receptor | 0.0462964 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0452965 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0444088 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0429875 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0420043 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.041991 |
| RAI14 | retinoic acid induced 14 | 0.0418856 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0417739 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0397476 |
| TXNRD1 | thioredoxin reductase 1 | 0.0390336 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0380653 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0376299 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0351305 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0347286 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0340887 |
| MED13L | mediator complex subunit 13-like | 0.032339 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0317369 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0315521 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0305767 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0272365 |
| VMP1 | vacuole membrane protein 1 | 0.026066 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0260055 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0242445 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0241984 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.024152 |
| PARD3 | par-3 family cell polarity regulator | 0.0239135 |
| RBM25 | RNA binding motif protein 25 | 0.0228646 |
| GLIS3 | GLIS family zinc finger 3 | 0.0226772 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0212596 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0212494 |
| GPHN | gephyrin | 0.021111 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0196196 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0188164 |
| NF1 | neurofibromin 1 | 0.0184251 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0179289 |
| RPS8 | ribosomal protein S8 | 0.016994 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0166795 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0154361 |
| CDH13 | cadherin 13 | 0.0152698 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0128601 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0126333 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0126196 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0124472 |
| CNKSR3 | CNKSR family member 3 | 0.0101146 |
| RPS12 | ribosomal protein S12 | 0.0100492 |
| GPC6 | glypican 6 | 0.00929858 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.00858913 |
| MYOF | myoferlin | 0.00747689 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00743228 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.00716287 |
| FAT1 | FAT atypical cadherin 1 | 0.00515229 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00485808 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.00426228 |
| TXNIP | thioredoxin interacting protein | 0.00418121 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.00390087 |
| ZNF609 | zinc finger protein 609 | 0.00267622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00203269 |
| RBM39 | RNA binding motif protein 39 | 0.00175152 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00136286 |
| NAMPT | nicotinamide phosphoribosyltransferase | 6.60635E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25287 |
| FN1 | fibronectin 1 | -0.194152 |
| VIM | vimentin | -0.159981 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.144632 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124853 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117633 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0926685 |
| TMSB10 | thymosin beta 10 | -0.089522 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0802658 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0777391 |
| PTMA | prothymosin, alpha | -0.0696923 |
| CANX | calnexin | -0.0646451 |
| PGK1 | phosphoglycerate kinase 1 | -0.0631264 |
| RPL26 | ribosomal protein L26 | -0.0629998 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0608848 |
| HDLBP | high density lipoprotein binding protein | -0.0579945 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0576176 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0559189 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0556506 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.054045 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0538255 |
| DST | dystonin | -0.0531335 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0527516 |
| EFNA5 | ephrin-A5 | -0.0493659 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.04861 |
| POTEF | POTE ankyrin domain family, member F | -0.0474969 |
| RTN4 | reticulon 4 | -0.0472916 |
| NRXN3 | neurexin 3 | -0.0452576 |
| CALR | calreticulin | -0.0436686 |
| RPS6 | ribosomal protein S6 | -0.0435155 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0429364 |
| CD44 | CD44 molecule (Indian blood group) | -0.0426488 |
| MORF4L2 | mortality factor 4 like 2 | -0.0418839 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0418026 |
| SMYD3 | SET and MYND domain containing 3 | -0.041745 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.038456 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0373932 |
| OGA | O-GlcNAcase | -0.0372302 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0369475 |
| GOLGA4 | golgin A4 | -0.0367874 |
| KIF5B | kinesin family member 5B | -0.0367367 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0360312 |
| CEP170 | centrosomal protein 170kDa | -0.0359977 |
| AHNAK | AHNAK nucleoprotein | -0.0358119 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.03446 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0337899 |
| OXR1 | oxidation resistance 1 | -0.0334929 |
| NDRG1 | N-myc downstream regulated 1 | -0.0328802 |
| RPL35A | ribosomal protein L35a | -0.0327824 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0327384 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0322329 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0319492 |
| ZNF292 | zinc finger protein 292 | -0.0305499 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0304711 |
| LDHA | lactate dehydrogenase A | -0.0300222 |
| GLG1 | golgi glycoprotein 1 | -0.0293005 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0290054 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0286024 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0284519 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0280408 |
| TMEM165 | transmembrane protein 165 | -0.0277211 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0274568 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0271449 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0268672 |
| TPR | translocated promoter region, nuclear basket protein | -0.0258523 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0253645 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0250869 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0249261 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0233848 |
| ACTG1 | actin gamma 1 | -0.0214419 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0212863 |
| FTL | ferritin, light polypeptide | -0.0209472 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0196003 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0194805 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0194006 |
| COL5A2 | collagen, type V, alpha 2 | -0.0179398 |
| INHBA | inhibin, beta A | -0.0179359 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0173228 |
| SEPTIN7 | septin 7 | -0.0166618 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0165207 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0157899 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.014882 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0136079 |
| ENO1 | enolase 1, (alpha) | -0.0135061 |
| RPLP1 | ribosomal protein, large, P1 | -0.0131458 |
| USP34 | ubiquitin specific peptidase 34 | -0.0114466 |
| B2M | beta-2-microglobulin | -0.0100385 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0093442 |
| BPTF | bromodomain PHD finger transcription factor | -0.00893104 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00828445 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.00827586 |
| JMJD1C | jumonji domain containing 1C | -0.00752725 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.00674004 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.00642528 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00472499 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00416128 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.00357817 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00333968 |
| DSCAM | Down syndrome cell adhesion molecule | -0.00261493 |
| FLNB | filamin B, beta | -0.00236098 |
