| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.144388 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.143038 |
| CADM2 | cell adhesion molecule 2 | 0.125446 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.120073 |
| NTM | neurotrimin | 0.113945 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.106065 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0980871 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0820282 |
| RPS6 | ribosomal protein S6 | 0.0805442 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0788427 |
| SNX6 | sorting nexin 6 | 0.0721289 |
| B2M | beta-2-microglobulin | 0.0720868 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0706978 |
| ITGAV | integrin, alpha V | 0.0651864 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0645253 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0611158 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0589648 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0542586 |
| RPS12 | ribosomal protein S12 | 0.0525127 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0521694 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0512375 |
| PRTG | protogenin | 0.050995 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0493604 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0473267 |
| PGK1 | phosphoglycerate kinase 1 | 0.0459767 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0458226 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0457931 |
| ATXN2 | ataxin 2 | 0.045611 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044363 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0438739 |
| GPC4 | glypican 4 | 0.043796 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0435392 |
| USP34 | ubiquitin specific peptidase 34 | 0.0407835 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0407428 |
| PRKD1 | protein kinase D1 | 0.0407183 |
| RPS2 | ribosomal protein S2 | 0.0405492 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0403512 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0400097 |
| BPTF | bromodomain PHD finger transcription factor | 0.039982 |
| TENM3 | teneurin transmembrane protein 3 | 0.0399231 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0398398 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0398311 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0392108 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0380904 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0378761 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0375292 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0372455 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0367855 |
| AFF1 | AF4/FMR2 family, member 1 | 0.036453 |
| RASAL2 | RAS protein activator like 2 | 0.0359793 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0357648 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0356382 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0353892 |
| DST | dystonin | 0.0351699 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0350737 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.034864 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0348167 |
| NHSL1 | NHS-like 1 | 0.0347654 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0345019 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0344406 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0342157 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0338836 |
| RIGI | RNA sensor RIG-I | 0.0334054 |
| TJP1 | tight junction protein 1 | 0.0333684 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.033238 |
| UTRN | utrophin | 0.0330751 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0330727 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0329115 |
| SRPK2 | SRSF protein kinase 2 | 0.0323731 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0322798 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0321677 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0318853 |
| PDS5B | PDS5 cohesin associated factor B | 0.0317688 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0316678 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0315866 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0308521 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0307513 |
| COL3A1 | collagen, type III, alpha 1 | 0.0307359 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0303504 |
| PLCB4 | phospholipase C, beta 4 | 0.0303366 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0297938 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0297602 |
| WAC | WW domain containing adaptor with coiled-coil | 0.029705 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0296502 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0292671 |
| WWC2 | WW and C2 domain containing 2 | 0.0291977 |
| CD2AP | CD2-associated protein | 0.0291623 |
| PTEN | phosphatase and tensin homolog | 0.0291053 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0287528 |
| PCDH9 | protocadherin 9 | 0.02872 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0283814 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0279022 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0277257 |
| FBXO11 | F-box protein 11 | 0.0277208 |
| SPAG9 | sperm associated antigen 9 | 0.027717 |
| GSE1 | Gse1 coiled-coil protein | 0.027596 |
| RREB1 | ras responsive element binding protein 1 | 0.0271606 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0270389 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0268575 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0268523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149075 |
| THBS1 | thrombospondin 1 | -0.100975 |
| GPC3 | glypican 3 | -0.0883564 |
| VIM | vimentin | -0.0828106 |
| TMSB4X | thymosin beta 4, X-linked | -0.0785713 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.071246 |
| PEG10 | paternally expressed 10 | -0.0706135 |
| ACTN4 | actinin, alpha 4 | -0.0679229 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0656114 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0642371 |
| ZNF292 | zinc finger protein 292 | -0.0605682 |
| AHNAK | AHNAK nucleoprotein | -0.0548572 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0530789 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0512752 |
| EMP1 | epithelial membrane protein 1 | -0.0498219 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0460668 |
| ACTG1 | actin gamma 1 | -0.0442724 |
| CAVIN1 | caveolae associated protein 1 | -0.0372095 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.037118 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0362692 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0356729 |
| PLPP1 | phospholipid phosphatase 1 | -0.0356472 |
| RPS16 | ribosomal protein S16 | -0.0355775 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0349754 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0346051 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.034496 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0340163 |
| MYO10 | myosin X | -0.033287 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0327304 |
| VGLL3 | vestigial-like family member 3 | -0.0324559 |
| HMGB1 | high mobility group box 1 | -0.0322915 |
| SHROOM3 | shroom family member 3 | -0.0321565 |
| CLTC | clathrin, heavy chain (Hc) | -0.0319649 |
| RPL19 | ribosomal protein L19 | -0.0317958 |
| EAPP | E2F-associated phosphoprotein | -0.0316218 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0315317 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0310949 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0309786 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0292706 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0288952 |
| USP3 | ubiquitin specific peptidase 3 | -0.0288761 |
| RPL7 | ribosomal protein L7 | -0.0285992 |
| PROS1 | protein S (alpha) | -0.0284097 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0282613 |
| QKI | QKI, KH domain containing, RNA binding | -0.0280121 |
| CERT1 | ceramide transporter 1 | -0.0279836 |
| DEK | DEK proto-oncogene | -0.0276348 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0273752 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0269939 |
| MATR3 | matrin 3 | -0.0269407 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0268797 |
| ANXA2 | annexin A2 | -0.0268654 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0268047 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0260604 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0259791 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0259528 |
| R3HDM1 | R3H domain containing 1 | -0.0259482 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0257439 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0256566 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0255881 |
| FLNA | filamin A, alpha | -0.0255421 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0255348 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.025432 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0253434 |
| CDK12 | cyclin-dependent kinase 12 | -0.0253231 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0252615 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0252604 |
| S100A10 | S100 calcium binding protein A10 | -0.0250582 |
| WDR70 | WD repeat domain 70 | -0.0249728 |
| COL5A2 | collagen, type V, alpha 2 | -0.0247284 |
| EXOC4 | exocyst complex component 4 | -0.0247258 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.024702 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0246859 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0244643 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0243712 |
| RPS21 | ribosomal protein S21 | -0.0239081 |
| PRELID2 | PRELI domain containing 2 | -0.0237418 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0233081 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0229425 |
| RTN4 | reticulon 4 | -0.0228061 |
| ARF1 | ADP-ribosylation factor 1 | -0.0225867 |
| AFDN | afadin, adherens junction formation factor | -0.0225591 |
| FNBP1L | formin binding protein 1-like | -0.0224684 |
| TPR | translocated promoter region, nuclear basket protein | -0.0223991 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0221815 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.022174 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0221552 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0218031 |
| ATG5 | autophagy related 5 | -0.0216882 |
| ZNF217 | zinc finger protein 217 | -0.0216331 |
| TMEM123 | transmembrane protein 123 | -0.0214208 |
| NF1 | neurofibromin 1 | -0.0212749 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.0211661 |
| RPL38 | ribosomal protein L38 | -0.0211296 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.0209024 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0209006 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.020865 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0207655 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.020752 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0206859 |
