| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.206287 |
| SFTPA2 | surfactant protein A2 | 0.116946 |
| YBX1 | Y box binding protein 1 | 0.110201 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.104741 |
| MT2A | metallothionein 2A | 0.099348 |
| RPS12 | ribosomal protein S12 | 0.0967505 |
| RPS6 | ribosomal protein S6 | 0.0926079 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0908597 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0875945 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.080104 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0756411 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0748698 |
| MKI67 | marker of proliferation Ki-67 | 0.0725917 |
| CENPF | centromere protein F, 350/400kDa | 0.0720137 |
| RPS3 | ribosomal protein S3 | 0.0695373 |
| ZFP36 | ZFP36 ring finger protein | 0.0643322 |
| RPS8 | ribosomal protein S8 | 0.064301 |
| RPS2 | ribosomal protein S2 | 0.0619512 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0604162 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0598382 |
| TPM3 | tropomyosin 3 | 0.0594217 |
| RPLP2 | ribosomal protein, large, P2 | 0.0585631 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0581881 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0570125 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0569579 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0563539 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0551073 |
| RPL23 | ribosomal protein L23 | 0.0530236 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0514735 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.05133 |
| RPS17 | ribosomal protein S17 | 0.0511328 |
| RPS19 | ribosomal protein S19 | 0.0505373 |
| RPL3 | ribosomal protein L3 | 0.0490924 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0482816 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.047428 |
| RPL37A | ribosomal protein L37a | 0.0467139 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0448608 |
| ASPH | aspartate beta-hydroxylase | 0.0444921 |
| GOLGB1 | golgin B1 | 0.0442066 |
| GOLGA4 | golgin A4 | 0.0437424 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0420151 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0392448 |
| RPL12 | ribosomal protein L12 | 0.0382663 |
| RPL21 | ribosomal protein L21 | 0.0375512 |
| MSN | moesin | 0.0372678 |
| RPL11 | ribosomal protein L11 | 0.0369933 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.036845 |
| TPX2 | TPX2, microtubule-associated | 0.0355665 |
| RPL36 | ribosomal protein L36 | 0.0353776 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0345288 |
| BRD2 | bromodomain containing 2 | 0.0344481 |
| INTS6 | integrator complex subunit 6 | 0.0337861 |
| B2M | beta-2-microglobulin | 0.0332665 |
| RPS23 | ribosomal protein S23 | 0.0327568 |
| RRM2 | ribonucleotide reductase M2 | 0.0324738 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0324137 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0322288 |
| RPL26 | ribosomal protein L26 | 0.0321943 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0320947 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0318156 |
| RPS4X | ribosomal protein S4, X-linked | 0.0316996 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0313452 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0313145 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.031106 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0303323 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0303244 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0300442 |
| YBX3 | Y box binding protein 3 | 0.0299661 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0293115 |
| RPL19 | ribosomal protein L19 | 0.029218 |
| DST | dystonin | 0.0291579 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291143 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0285622 |
| RPL32 | ribosomal protein L32 | 0.0276481 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0273749 |
| DNMBP | dynamin binding protein | 0.0268894 |
| CCDC88A | coiled-coil domain containing 88A | 0.0267554 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0267357 |
| VEGFA | vascular endothelial growth factor A | 0.0266758 |
| ZNF146 | zinc finger protein 146 | 0.0264289 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0258998 |
| VMP1 | vacuole membrane protein 1 | 0.0256035 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0255201 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0252989 |
| SMAD3 | SMAD family member 3 | 0.0252881 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0252781 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0251054 |
| RPL8 | ribosomal protein L8 | 0.0250991 |
| RSF1 | remodeling and spacing factor 1 | 0.025041 |
| SMYD3 | SET and MYND domain containing 3 | 0.0250248 |
| SON | SON DNA binding protein | 0.0249706 |
| SET | SET nuclear proto-oncogene | 0.024942 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0248855 |
| AHNAK | AHNAK nucleoprotein | 0.0247555 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0247093 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0245696 |
| OGA | O-GlcNAcase | 0.0243931 |
| RPL28 | ribosomal protein L28 | 0.0242993 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.024266 |
| ACTN4 | actinin, alpha 4 | 0.0242015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.311768 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119088 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.102516 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0987845 |
| PTMA | prothymosin, alpha | -0.0975077 |
| RPS16 | ribosomal protein S16 | -0.087521 |
| ACTG1 | actin gamma 1 | -0.0813892 |
| CTSD | cathepsin D | -0.064403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0599007 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0577659 |
| TMEM123 | transmembrane protein 123 | -0.0575791 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0546915 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0508662 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0488363 |
| S100A6 | S100 calcium binding protein A6 | -0.0467033 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0461671 |
| RPLP0 | ribosomal protein, large, P0 | -0.0432144 |
| ANXA2 | annexin A2 | -0.0429486 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0429313 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0423833 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0413417 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0400976 |
| RPS24 | ribosomal protein S24 | -0.0400421 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0376289 |
| RNF220 | ring finger protein 220 | -0.0368572 |
| CD44 | CD44 molecule (Indian blood group) | -0.0360548 |
| LDHA | lactate dehydrogenase A | -0.0357199 |
| CD109 | CD109 molecule | -0.0335228 |
| MYOF | myoferlin | -0.0327325 |
| ATG7 | autophagy related 7 | -0.0310578 |
| DIAPH2 | diaphanous-related formin 2 | -0.0307179 |
| EGFR | epidermal growth factor receptor | -0.0306726 |
| HMGA1 | high mobility group AT-hook 1 | -0.0304252 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0303655 |
| TUBB | tubulin, beta class I | -0.0291309 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0290336 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0289984 |
| FTL | ferritin, light polypeptide | -0.0289153 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0282999 |
| HMGA2 | high mobility group AT-hook 2 | -0.0281168 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0270113 |
| AFAP1 | actin filament associated protein 1 | -0.0269732 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0265719 |
| RIGI | RNA sensor RIG-I | -0.0255487 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.025111 |
| PGK1 | phosphoglycerate kinase 1 | -0.0251005 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0248236 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0244656 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0228888 |
| RASAL2 | RAS protein activator like 2 | -0.0227109 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.022574 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0223842 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.022259 |
| VCL | vinculin | -0.0219808 |
| NF1 | neurofibromin 1 | -0.0218774 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0218494 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0218425 |
| MYADM | myeloid-associated differentiation marker | -0.0218394 |
| EHBP1 | EH domain binding protein 1 | -0.0216686 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.021599 |
| MEF2A | myocyte enhancer factor 2A | -0.021577 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0214633 |
| RPL27A | ribosomal protein L27a | -0.0213982 |
| LMNA | lamin A/C | -0.0212764 |
| CAVIN1 | caveolae associated protein 1 | -0.0207276 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0206832 |
| REEP3 | receptor accessory protein 3 | -0.0204712 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0201929 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0201846 |
| RPL39 | ribosomal protein L39 | -0.0197075 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0194026 |
| NHSL1 | NHS-like 1 | -0.0192989 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0192633 |
| FHL2 | four and a half LIM domains 2 | -0.0192258 |
| ENO1 | enolase 1, (alpha) | -0.0191377 |
| CD164 | CD164 molecule, sialomucin | -0.0190272 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.019012 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0188879 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0188302 |
| H1-0 | H1.0 linker histone | -0.0188115 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0188037 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0187359 |
| CCND1 | cyclin D1 | -0.018734 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0185981 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0184578 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0183197 |
| FBXO17 | F-box protein 17 | -0.0182484 |
| ABLIM1 | actin binding LIM protein 1 | -0.0180378 |
| MYO1E | myosin IE | -0.0180268 |
| ARF1 | ADP-ribosylation factor 1 | -0.0179421 |
| KRT19 | keratin 19, type I | -0.0178816 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0178377 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0176075 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0176024 |
| TNS3 | tensin 3 | -0.0175981 |
| SBF2 | SET binding factor 2 | -0.015937 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0156254 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0153796 |
| PRSS23 | protease, serine, 23 | -0.015103 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0150887 |