| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.222752 |
| RPS6 | ribosomal protein S6 | 0.174646 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.174496 |
| LAMC2 | laminin, gamma 2 | 0.130146 |
| DSG2 | desmoglein 2 | 0.117493 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.104227 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.101365 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0797687 |
| TMSB4X | thymosin beta 4, X-linked | 0.0740645 |
| RPL12 | ribosomal protein L12 | 0.0699076 |
| LAMA4 | laminin, alpha 4 | 0.0687248 |
| KRT18 | keratin 18, type I | 0.068118 |
| LMO7 | LIM domain 7 | 0.0676083 |
| RPS8 | ribosomal protein S8 | 0.0656326 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0628453 |
| MT2A | metallothionein 2A | 0.0614029 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0602087 |
| RPS12 | ribosomal protein S12 | 0.0582699 |
| RPS19 | ribosomal protein S19 | 0.0582021 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0557439 |
| RPS21 | ribosomal protein S21 | 0.0553294 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.054981 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0546244 |
| RPL19 | ribosomal protein L19 | 0.0544648 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0540866 |
| AFDN | afadin, adherens junction formation factor | 0.0537685 |
| MYO5B | myosin VB | 0.0515284 |
| TXNIP | thioredoxin interacting protein | 0.0512972 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0495292 |
| YBX1 | Y box binding protein 1 | 0.048364 |
| DSPP | dentin sialophosphoprotein | 0.0481072 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0480581 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0473812 |
| GOLGB1 | golgin B1 | 0.0463456 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0459653 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0459607 |
| RPL32 | ribosomal protein L32 | 0.0452287 |
| RPS3 | ribosomal protein S3 | 0.0442547 |
| RPS2 | ribosomal protein S2 | 0.0441775 |
| RPL36 | ribosomal protein L36 | 0.0438584 |
| TPM3 | tropomyosin 3 | 0.0433562 |
| RPL26 | ribosomal protein L26 | 0.0425202 |
| RPL34 | ribosomal protein L34 | 0.04232 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0414181 |
| RPL8 | ribosomal protein L8 | 0.0409907 |
| RPS4X | ribosomal protein S4, X-linked | 0.0409679 |
| EMP1 | epithelial membrane protein 1 | 0.0402927 |
| TPI1 | triosephosphate isomerase 1 | 0.0393107 |
| G0S2 | G0/G1 switch 2 | 0.0390737 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0383651 |
| INHBA | inhibin, beta A | 0.0381102 |
| SFTPA2 | surfactant protein A2 | 0.0372452 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0366431 |
| RPL18 | ribosomal protein L18 | 0.0361469 |
| MKI67 | marker of proliferation Ki-67 | 0.0354595 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0352643 |
| DST | dystonin | 0.035164 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0345325 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0345174 |
| EHF | ets homologous factor | 0.0341662 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0338413 |
| AREG | amphiregulin | 0.0335948 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0334998 |
| KLF6 | Kruppel-like factor 6 | 0.0334263 |
| SLK | STE20-like kinase | 0.0333794 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0332918 |
| YBX3 | Y box binding protein 3 | 0.0325584 |
| PLAU | plasminogen activator, urokinase | 0.0320887 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0312782 |
| RPL3 | ribosomal protein L3 | 0.0310608 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0297879 |
| AHNAK | AHNAK nucleoprotein | 0.0297464 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.029388 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0291991 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291844 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0291675 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0291351 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0290797 |
| MT1X | metallothionein 1X | 0.0287738 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.028685 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0286774 |
| RPL23A | ribosomal protein L23a | 0.0286466 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0285471 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0283192 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0280861 |
| RPL14 | ribosomal protein L14 | 0.0276751 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.027453 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0269176 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0268951 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0267888 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0267548 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0265758 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0264566 |
| RPL11 | ribosomal protein L11 | 0.0263897 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0262857 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0262256 |
| TMF1 | TATA element modulatory factor 1 | 0.0262069 |
| BCL2L1 | BCL2-like 1 | 0.0255988 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0255289 |
| RPL21 | ribosomal protein L21 | 0.0253644 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122939 |
| PTMA | prothymosin, alpha | -0.113113 |
| MUC4 | mucin 4, cell surface associated | -0.112708 |
| KRT17 | keratin 17, type I | -0.0852287 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0799809 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0792899 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0698426 |
| PCBP2 | poly(rC) binding protein 2 | -0.0670643 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0655892 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0621649 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0579673 |
| EFNA5 | ephrin-A5 | -0.0555138 |
| C3 | complement component 3 | -0.0520785 |
| MUC16 | mucin 16, cell surface associated | -0.0520731 |
| UBC | ubiquitin C | -0.051778 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0516248 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0511591 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0504508 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0491491 |
| POTEF | POTE ankyrin domain family, member F | -0.0464584 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0456432 |
| FTL | ferritin, light polypeptide | -0.0439603 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.043874 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0428056 |
| LDHA | lactate dehydrogenase A | -0.0413411 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0408506 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0399131 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0394871 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0390567 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0383405 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0382855 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0382168 |
| TPM4 | tropomyosin 4 | -0.0379421 |
| RNF213 | ring finger protein 213 | -0.037381 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0371156 |
| ZNF207 | zinc finger protein 207 | -0.0366564 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.036407 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0359938 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0358496 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0356694 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0345413 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0342188 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0340207 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0340179 |
| CANX | calnexin | -0.0337323 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0336491 |
| ETV6 | ets variant 6 | -0.0335082 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0320323 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0320178 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0315378 |
| STK24 | serine/threonine kinase 24 | -0.0312379 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0310701 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0309668 |
| RBM47 | RNA binding motif protein 47 | -0.0308154 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0296988 |
| BBX | bobby sox homolog (Drosophila) | -0.0291153 |
| TFG | TRK-fused gene | -0.028664 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0286432 |
| OXSR1 | oxidative stress responsive 1 | -0.0283356 |
| PKM | pyruvate kinase, muscle | -0.0282969 |
| TC2N | tandem C2 domains, nuclear | -0.0282108 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0281814 |
| TAPBP | TAP binding protein (tapasin) | -0.0280186 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.027905 |
| KRT7 | keratin 7, type II | -0.0278577 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0277852 |
| RPL31 | ribosomal protein L31 | -0.0275987 |
| DPYD | dihydropyrimidine dehydrogenase | -0.027573 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0275681 |
| KLHL24 | kelch-like family member 24 | -0.0274773 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.027342 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0271369 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.027019 |
| CCNY | cyclin Y | -0.0268766 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0266292 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0264251 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0262809 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0261088 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0259161 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0257365 |
| WDR45B | WD repeat domain 45B | -0.0257018 |
| CALR | calreticulin | -0.0254563 |
| PTK2 | protein tyrosine kinase 2 | -0.0252481 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251422 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0251091 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0248743 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.02468 |
| CTSD | cathepsin D | -0.0246763 |
| ATP11A | ATPase, class VI, type 11A | -0.0245089 |
| RPS27A | ribosomal protein S27a | -0.0244001 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0243443 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0243129 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.024236 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0238634 |
| RYBP | RING1 and YY1 binding protein | -0.0237072 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0236074 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0235098 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0235026 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0231958 |
| DAPK1 | death-associated protein kinase 1 | -0.0231059 |
