| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.152611 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.114745 |
| RPL3 | ribosomal protein L3 | 0.106078 |
| MCL1 | myeloid cell leukemia 1 | 0.104781 |
| RPS6 | ribosomal protein S6 | 0.0985546 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0675353 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0630643 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0626834 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0614611 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0591448 |
| CORO1C | coronin, actin binding protein, 1C | 0.0589108 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0586174 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0556199 |
| AHNAK | AHNAK nucleoprotein | 0.054833 |
| JMJD1C | jumonji domain containing 1C | 0.0534966 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0527409 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0522345 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0507922 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0491492 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0485189 |
| NAV2 | neuron navigator 2 | 0.0479424 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0478667 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0459737 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0457107 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0443679 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.044172 |
| CAPRIN2 | caprin family member 2 | 0.0433649 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0419608 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0414814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0400952 |
| GOLGA4 | golgin A4 | 0.0399838 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0391136 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0375793 |
| OGA | O-GlcNAcase | 0.0375408 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0368477 |
| RPL14 | ribosomal protein L14 | 0.0351031 |
| GLRX | glutaredoxin (thioltransferase) | 0.0349743 |
| DGKI | diacylglycerol kinase, iota | 0.0348368 |
| TPM3 | tropomyosin 3 | 0.0344645 |
| YBX1 | Y box binding protein 1 | 0.0340779 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0337645 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0334059 |
| BRD2 | bromodomain containing 2 | 0.0332742 |
| SON | SON DNA binding protein | 0.0332167 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0330948 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0329741 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0329033 |
| ANO6 | anoctamin 6 | 0.0328898 |
| UBC | ubiquitin C | 0.0328844 |
| ASPH | aspartate beta-hydroxylase | 0.0323224 |
| SGMS2 | sphingomyelin synthase 2 | 0.0314942 |
| SETX | senataxin | 0.0309382 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.03076 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0307061 |
| VMP1 | vacuole membrane protein 1 | 0.0303399 |
| GSE1 | Gse1 coiled-coil protein | 0.030125 |
| MKI67 | marker of proliferation Ki-67 | 0.0297278 |
| GOLGB1 | golgin B1 | 0.0296287 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0295358 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0294162 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0292048 |
| RPL8 | ribosomal protein L8 | 0.0289492 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0287748 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0287633 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0286887 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0286411 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0283038 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0282203 |
| JUN | jun proto-oncogene | 0.0280515 |
| GPATCH2L | G patch domain containing 2-like | 0.0280498 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0280082 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0275009 |
| DST | dystonin | 0.0273928 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0271887 |
| RUNX1 | runt-related transcription factor 1 | 0.0269392 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.0269096 |
| TMF1 | TATA element modulatory factor 1 | 0.02667 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0265155 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0261293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0258225 |
| PRELID2 | PRELI domain containing 2 | 0.025805 |
| RPS2 | ribosomal protein S2 | 0.0257879 |
| NCKAP1 | NCK-associated protein 1 | 0.0257592 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0255258 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0254894 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0254039 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0252412 |
| G0S2 | G0/G1 switch 2 | 0.0251624 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0250093 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0248511 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0247981 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0247963 |
| NUDC | nudC nuclear distribution protein | 0.0247834 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0246465 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0246004 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0245681 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0238177 |
| EMP1 | epithelial membrane protein 1 | 0.023796 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0234496 |
| SMTN | smoothelin | 0.0234141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.109505 |
| ZNF438 | zinc finger protein 438 | -0.089096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0854143 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0830706 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0682724 |
| RPS24 | ribosomal protein S24 | -0.0677168 |
| RPL30 | ribosomal protein L30 | -0.0625671 |
| TTR | transthyretin | -0.0595498 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.056397 |
| FRMD4A | FERM domain containing 4A | -0.0563144 |
| BNC2 | basonuclin 2 | -0.0559111 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0530283 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0517274 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0511299 |
| PTMA | prothymosin, alpha | -0.0501119 |
| MTAP | methylthioadenosine phosphorylase | -0.049924 |
| HMGA2 | high mobility group AT-hook 2 | -0.0470522 |
| ACTG1 | actin gamma 1 | -0.0431591 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0431268 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0401897 |
| RPLP0 | ribosomal protein, large, P0 | -0.039925 |
| RIGI | RNA sensor RIG-I | -0.0399092 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.039848 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0382014 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0373246 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0366729 |
| NAV3 | neuron navigator 3 | -0.036226 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.035713 |
| LDHA | lactate dehydrogenase A | -0.0345622 |
| TPM4 | tropomyosin 4 | -0.0338695 |
| RPL9 | ribosomal protein L9 | -0.0336302 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330677 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0327646 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0315955 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0301276 |
| NABP1 | nucleic acid binding protein 1 | -0.030094 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.029892 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0297682 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0295066 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0287823 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287247 |
| DIAPH3 | diaphanous-related formin 3 | -0.0283111 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0280982 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0276655 |
| CALD1 | caldesmon 1 | -0.0276103 |
| RPL35A | ribosomal protein L35a | -0.0266181 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0265319 |
| RPS25 | ribosomal protein S25 | -0.0264794 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0259266 |
| TUBA1C | tubulin, alpha 1c | -0.0253009 |
| RPS3 | ribosomal protein S3 | -0.0251049 |
| RAB3IP | RAB3A interacting protein | -0.0251039 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.024952 |
| RPL31 | ribosomal protein L31 | -0.0249484 |
| TUBA1B | tubulin, alpha 1b | -0.0248953 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0247726 |
| FHIT | fragile histidine triad | -0.0243603 |
| RPS20 | ribosomal protein S20 | -0.0239022 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0238911 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238439 |
| MT2A | metallothionein 2A | -0.0238319 |
| ARF1 | ADP-ribosylation factor 1 | -0.0234128 |
| GNAS | GNAS complex locus | -0.0232888 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0232827 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0232675 |
| CD44 | CD44 molecule (Indian blood group) | -0.0226775 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.022581 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0220933 |
| RPL13A | ribosomal protein L13a | -0.0219568 |
| TCF12 | transcription factor 12 | -0.0218722 |
| FTL | ferritin, light polypeptide | -0.0218159 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0216131 |
| WDR45B | WD repeat domain 45B | -0.0214794 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0209942 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0200826 |
| PCNX4 | pecanex 4 | -0.0198554 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0198485 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0196822 |
| RPL38 | ribosomal protein L38 | -0.0195923 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0194218 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.019301 |
| HMGA1 | high mobility group AT-hook 1 | -0.0189545 |
| TUBB | tubulin, beta class I | -0.0189427 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0189244 |
| RAB14 | RAB14, member RAS oncogene family | -0.0188864 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.018855 |
| USP3 | ubiquitin specific peptidase 3 | -0.0188034 |
| CANX | calnexin | -0.0187359 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0184354 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0184208 |
| HLA-C | major histocompatibility complex, class I, C | -0.0184032 |
| SP100 | SP100 nuclear antigen | -0.0182441 |
| HLA-B | major histocompatibility complex, class I, B | -0.0182199 |
| TMEM123 | transmembrane protein 123 | -0.0181104 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0178787 |
| RPL15 | ribosomal protein L15 | -0.0177906 |
| CDK6 | cyclin-dependent kinase 6 | -0.0175174 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.017402 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0173974 |
| CALR | calreticulin | -0.017317 |
