| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.205274 |
| STC1 | stanniocalcin 1 | 0.161639 |
| B2M | beta-2-microglobulin | 0.144411 |
| VEGFA | vascular endothelial growth factor A | 0.143573 |
| NDRG1 | N-myc downstream regulated 1 | 0.128901 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.118683 |
| RPS6 | ribosomal protein S6 | 0.0937479 |
| FN1 | fibronectin 1 | 0.0927379 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0794278 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0773375 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0762673 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0662131 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0650982 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0595368 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0592206 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0556302 |
| ANGPTL4 | angiopoietin-like 4 | 0.0552924 |
| GOLGB1 | golgin B1 | 0.0552746 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0547942 |
| INHBA | inhibin, beta A | 0.0546053 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0541473 |
| HDAC9 | histone deacetylase 9 | 0.0531086 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0508392 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0469655 |
| FAT1 | FAT atypical cadherin 1 | 0.0458918 |
| TGM2 | transglutaminase 2 | 0.0449024 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0442226 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0418893 |
| SFTPA2 | surfactant protein A2 | 0.0417168 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0414418 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.039761 |
| MMP2 | matrix metallopeptidase 2 | 0.0380462 |
| YBX1 | Y box binding protein 1 | 0.0377752 |
| BRD2 | bromodomain containing 2 | 0.0365211 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0352059 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0333637 |
| FBXO32 | F-box protein 32 | 0.0333534 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0332628 |
| COL5A3 | collagen, type V, alpha 3 | 0.0322481 |
| RPS8 | ribosomal protein S8 | 0.0321272 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0315032 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0314454 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0308557 |
| IL6 | interleukin 6 | 0.0307801 |
| TPM3 | tropomyosin 3 | 0.0306108 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0292914 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0289915 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0279711 |
| EGR1 | early growth response 1 | 0.0277902 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0276924 |
| ARRDC3 | arrestin domain containing 3 | 0.0268361 |
| DST | dystonin | 0.0264111 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.026163 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0259174 |
| RPL11 | ribosomal protein L11 | 0.0258536 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0258079 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0257849 |
| RPL3 | ribosomal protein L3 | 0.0256273 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255824 |
| ATF4 | activating transcription factor 4 | 0.0255746 |
| RPS19 | ribosomal protein S19 | 0.02546 |
| GOLGA4 | golgin A4 | 0.0253935 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.02534 |
| S100A9 | S100 calcium binding protein A9 | 0.0253354 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0253329 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0252537 |
| TGFB1 | transforming growth factor, beta 1 | 0.0250413 |
| RPL19 | ribosomal protein L19 | 0.0247002 |
| TMF1 | TATA element modulatory factor 1 | 0.0244816 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0244637 |
| FAM162A | family with sequence similarity 162, member A | 0.0243202 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0242298 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0242091 |
| CCDC88A | coiled-coil domain containing 88A | 0.0238898 |
| RPS17 | ribosomal protein S17 | 0.0238198 |
| GCNA | germ cell nuclear acidic peptidase | 0.0236224 |
| IFI44L | interferon-induced protein 44-like | 0.0235259 |
| RPL32 | ribosomal protein L32 | 0.0234495 |
| CCNL1 | cyclin L1 | 0.0233943 |
| MSN | moesin | 0.0233585 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0230601 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0228634 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0227112 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0225526 |
| SVIL | supervillin | 0.0225434 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0224938 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0224912 |
| RPS12 | ribosomal protein S12 | 0.0224297 |
| ECE1 | endothelin converting enzyme 1 | 0.0223563 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.022334 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0222541 |
| SETBP1 | SET binding protein 1 | 0.0221924 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0218309 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0216908 |
| RPS2 | ribosomal protein S2 | 0.0215465 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0215078 |
| ZNF395 | zinc finger protein 395 | 0.0212868 |
| CLIC4 | chloride intracellular channel 4 | 0.0211284 |
| CLU | clusterin | 0.0209469 |
| CCN4 | cellular communication network factor 4 | 0.020931 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.254466 |
| COL1A1 | collagen, type I, alpha 1 | -0.160662 |
| CDH13 | cadherin 13 | -0.106214 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0997682 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0880872 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0779358 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0764772 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0633126 |
| CALU | calumenin | -0.0631955 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0624067 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0623437 |
| TPM4 | tropomyosin 4 | -0.0608116 |
| MMP12 | matrix metallopeptidase 12 | -0.0577411 |
| PGK1 | phosphoglycerate kinase 1 | -0.0546197 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0543493 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0523639 |
| TPM1 | tropomyosin 1 (alpha) | -0.0522186 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0500776 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0490782 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0468032 |
| MTSS1 | metastasis suppressor 1 | -0.0454154 |
| FRMD4A | FERM domain containing 4A | -0.0451698 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0430707 |
| IER3 | immediate early response 3 | -0.0430012 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0411829 |
| VCAN | versican | -0.0408498 |
| FMNL2 | formin-like 2 | -0.0396027 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0393883 |
| RPS27A | ribosomal protein S27a | -0.039026 |
| TNNC1 | troponin C type 1 (slow) | -0.0386388 |
| MT2A | metallothionein 2A | -0.0378002 |
| UBC | ubiquitin C | -0.037044 |
| FAM20C | family with sequence similarity 20, member C | -0.0367217 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0354056 |
| CENPF | centromere protein F, 350/400kDa | -0.0352816 |
| LOXL2 | lysyl oxidase-like 2 | -0.0352645 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0349468 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0345236 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0344019 |
| VCL | vinculin | -0.0342239 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0335048 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0325591 |
| ACTG1 | actin gamma 1 | -0.0324552 |
| PTMA | prothymosin, alpha | -0.0319467 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0318289 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0317579 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0317508 |
| EGFR | epidermal growth factor receptor | -0.0315066 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0313098 |
| FBN1 | fibrillin 1 | -0.0311026 |
| SSH1 | slingshot protein phosphatase 1 | -0.030979 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0306738 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0306513 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0300711 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0299609 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0295464 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0286828 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0285845 |
| TPX2 | TPX2, microtubule-associated | -0.0285283 |
| TMEM165 | transmembrane protein 165 | -0.0284058 |
| ACTN1 | actinin, alpha 1 | -0.0281766 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0281486 |
| CADM1 | cell adhesion molecule 1 | -0.0278173 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0277735 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0276558 |
| DIAPH3 | diaphanous-related formin 3 | -0.0274186 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0273914 |
| ITGA1 | integrin, alpha 1 | -0.0271118 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0269435 |
| ATXN1 | ataxin 1 | -0.0269022 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0265627 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0263142 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0262861 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0262014 |
| FLNA | filamin A, alpha | -0.0260353 |
| MLPH | melanophilin | -0.0256621 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0255498 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0254516 |
| HMGB2 | high mobility group box 2 | -0.025257 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0251843 |
| NBAS | neuroblastoma amplified sequence | -0.0249814 |
| TNS3 | tensin 3 | -0.0249474 |
| POTEF | POTE ankyrin domain family, member F | -0.0248842 |
| RIGI | RNA sensor RIG-I | -0.0247899 |
| FAM107B | family with sequence similarity 107, member B | -0.0246558 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0244649 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0242038 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0241954 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0241608 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0240488 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0236982 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0236171 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0234008 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0231918 |
| NUMB | numb homolog (Drosophila) | -0.0230605 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0229685 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0229362 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0229305 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.0229023 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0228788 |
