| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.21826 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.116005 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.115337 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.111808 |
| NRG1 | neuregulin 1 | 0.0933645 |
| GPC6 | glypican 6 | 0.0828037 |
| SMYD3 | SET and MYND domain containing 3 | 0.0822588 |
| STC1 | stanniocalcin 1 | 0.0812448 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.079024 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0776785 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0738287 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0703385 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0676828 |
| ENO1 | enolase 1, (alpha) | 0.0660096 |
| NBEA | neurobeachin | 0.0651436 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0642345 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.0628316 |
| NCKAP5 | NCK-associated protein 5 | 0.0623803 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0618608 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0612633 |
| CNKSR3 | CNKSR family member 3 | 0.0595949 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0573615 |
| CPE | carboxypeptidase E | 0.0570445 |
| TOX | thymocyte selection-associated high mobility group box | 0.0556785 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0533502 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0517757 |
| KIF26B | kinesin family member 26B | 0.0512226 |
| SCG2 | secretogranin II | 0.0501523 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0491028 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0490786 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0490072 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.048296 |
| SNTG1 | syntrophin, gamma 1 | 0.047831 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0475291 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0464603 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0455807 |
| CHGB | chromogranin B | 0.0452198 |
| NDRG1 | N-myc downstream regulated 1 | 0.0441678 |
| RORA | RAR-related orphan receptor A | 0.0440861 |
| RIGI | RNA sensor RIG-I | 0.0438972 |
| MCL1 | myeloid cell leukemia 1 | 0.0433864 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.042674 |
| VGF | VGF nerve growth factor inducible | 0.0416286 |
| INHBA | inhibin, beta A | 0.0412299 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0400339 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | 0.0399469 |
| NAV2 | neuron navigator 2 | 0.0399049 |
| ASPH | aspartate beta-hydroxylase | 0.0394288 |
| RNF213 | ring finger protein 213 | 0.0394133 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0392755 |
| MX2 | MX dynamin-like GTPase 2 | 0.0389819 |
| ARFGEF3 | ARFGEF family member 3 | 0.0386977 |
| SVIL | supervillin | 0.0380223 |
| EPHA6 | EPH receptor A6 | 0.0379963 |
| TPM3 | tropomyosin 3 | 0.0375551 |
| ESRRG | estrogen-related receptor gamma | 0.0373275 |
| PTCHD4 | patched domain containing 4 | 0.0366715 |
| GPC5 | glypican 5 | 0.0364085 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0361176 |
| TMSB4X | thymosin beta 4, X-linked | 0.03572 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0355853 |
| RIT2 | Ras-like without CAAX 2 | 0.0351252 |
| FAM13A | family with sequence similarity 13, member A | 0.0350831 |
| EFNA5 | ephrin-A5 | 0.0345677 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0341678 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0338473 |
| PLSCR1 | phospholipid scramblase 1 | 0.0336494 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0335116 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0325517 |
| AOPEP | aminopeptidase O (putative) | 0.0322412 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321339 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0312035 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0308895 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0307237 |
| TXNRD1 | thioredoxin reductase 1 | 0.0305805 |
| FGF14 | fibroblast growth factor 14 | 0.03036 |
| HMGB3 | high mobility group box 3 | 0.0301964 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | 0.0297923 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0297768 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0296145 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.029476 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0294303 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0286048 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | 0.0281812 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.028101 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0280368 |
| NAV1 | neuron navigator 1 | 0.0279663 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0277876 |
| TRIM9 | tripartite motif containing 9 | 0.0277263 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0271384 |
| MT2A | metallothionein 2A | 0.0270964 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0270963 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.026946 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0268874 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0266533 |
| SIK2 | salt-inducible kinase 2 | 0.0265885 |
| LSAMP | limbic system-associated membrane protein | 0.0265731 |
| SP100 | SP100 nuclear antigen | 0.0262804 |
| ADAR | adenosine deaminase, RNA-specific | 0.0259157 |
| NELL1 | NEL-like 1 (chicken) | 0.0242628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.124282 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0830516 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0680189 |
| CENPF | centromere protein F, 350/400kDa | -0.0586908 |
| TENM1 | teneurin transmembrane protein 1 | -0.0552001 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0348492 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0345458 |
| FTL | ferritin, light polypeptide | -0.0338691 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.026163 |
| XPO1 | exportin 1 | -0.0250713 |
| TPX2 | TPX2, microtubule-associated | -0.0246685 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0244467 |
| SGO2 | shugoshin 2 | -0.0243243 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0239395 |
| MKI67 | marker of proliferation Ki-67 | -0.0235378 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0234237 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0233677 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0232238 |
| KNL1 | kinetochore scaffold 1 | -0.022783 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0225006 |
| HMGB2 | high mobility group box 2 | -0.0223156 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0223013 |
| TTK | TTK protein kinase | -0.022096 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0218644 |
| NKTR | natural killer cell triggering receptor | -0.0215525 |
| ECT2 | epithelial cell transforming 2 | -0.021465 |
| KIF14 | kinesin family member 14 | -0.0213435 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0213142 |
| CENPE | centromere protein E, 312kDa | -0.0211531 |
| RPL23 | ribosomal protein L23 | -0.0210716 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0210174 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0202816 |
| CDCA2 | cell division cycle associated 2 | -0.0199269 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0197188 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0190066 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0190008 |
| RPS21 | ribosomal protein S21 | -0.0189921 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0189891 |
| RPS27A | ribosomal protein S27a | -0.0189676 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0187249 |
| AGMO | alkylglycerol monooxygenase | -0.0183428 |
| RPL35A | ribosomal protein L35a | -0.0182787 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0182372 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0181895 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0181492 |
| CALCA | calcitonin-related polypeptide alpha | -0.0180309 |
| JAM3 | junctional adhesion molecule 3 | -0.0179369 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0177733 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0177502 |
| CEP152 | centrosomal protein 152kDa | -0.017695 |
| TUBB | tubulin, beta class I | -0.0176733 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0174806 |
| AFF1 | AF4/FMR2 family, member 1 | -0.017259 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0172056 |
| RPLP0 | ribosomal protein, large, P0 | -0.0171953 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -0.017113 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0167184 |
| KIF4A | kinesin family member 4A | -0.0166831 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0165817 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0164992 |
| ANLN | anillin, actin binding protein | -0.0163267 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.016303 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0160258 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0160223 |
| FAM162A | family with sequence similarity 162, member A | -0.0159236 |
| RPLP1 | ribosomal protein, large, P1 | -0.0159012 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0155871 |
| FOXC1 | forkhead box C1 | -0.0154936 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0154785 |
| RPL26 | ribosomal protein L26 | -0.0153978 |
| DEK | DEK proto-oncogene | -0.0153361 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0152417 |
| PBK | PDZ binding kinase | -0.0152346 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0151308 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0150478 |
| PHIP | pleckstrin homology domain interacting protein | -0.0148969 |
| PRR11 | proline rich 11 | -0.0146153 |
| OGA | O-GlcNAcase | -0.0145107 |
| INTS6 | integrator complex subunit 6 | -0.0144731 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0144729 |
| NFIA | nuclear factor I/A | -0.014406 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0144045 |
| SMC4 | structural maintenance of chromosomes 4 | -0.014367 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.014234 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0141958 |
| FUS | FUS RNA binding protein | -0.0141018 |
| CA8 | carbonic anhydrase VIII | -0.0141016 |
| RPS24 | ribosomal protein S24 | -0.0140735 |
| RPL32 | ribosomal protein L32 | -0.0140176 |
| DIAPH3 | diaphanous-related formin 3 | -0.0139906 |
| H1-0 | H1.0 linker histone | -0.0139797 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0139112 |
| S100A9 | S100 calcium binding protein A9 | -0.0138725 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0137636 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0136903 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0136126 |
| WDR45B | WD repeat domain 45B | -0.0135203 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -0.0135162 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0134919 |
| KIF2C | kinesin family member 2C | -0.013415 |
