| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.160883 |
| NRG3 | neuregulin 3 | 0.159758 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.13136 |
| LSAMP | limbic system-associated membrane protein | 0.126075 |
| NLGN1 | neuroligin 1 | 0.0875976 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.084207 |
| SFTPA2 | surfactant protein A2 | 0.0816284 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0806127 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0764301 |
| EHBP1 | EH domain binding protein 1 | 0.0684825 |
| RAD51B | RAD51 paralog B | 0.064268 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0632912 |
| ASPH | aspartate beta-hydroxylase | 0.0593481 |
| ANGPTL4 | angiopoietin-like 4 | 0.0578413 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0572521 |
| RPS6 | ribosomal protein S6 | 0.0556359 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0550432 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0534561 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.051692 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0514579 |
| FHIT | fragile histidine triad | 0.0507081 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0496085 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0491667 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0479306 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0470998 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0466762 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0443612 |
| AHNAK | AHNAK nucleoprotein | 0.0443001 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0439982 |
| ATXN1 | ataxin 1 | 0.043865 |
| RRBP1 | ribosome binding protein 1 | 0.0437459 |
| CFAP20DC | CFAP20 domain containing | 0.0434809 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.043421 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0433728 |
| SVIL | supervillin | 0.042761 |
| GOLGB1 | golgin B1 | 0.0421028 |
| MSI2 | musashi RNA-binding protein 2 | 0.0409364 |
| SP100 | SP100 nuclear antigen | 0.0405912 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0397935 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0394205 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0388669 |
| RNF213 | ring finger protein 213 | 0.037692 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0376478 |
| B2M | beta-2-microglobulin | 0.0373745 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0370423 |
| TMSB10 | thymosin beta 10 | 0.0360854 |
| CTBP2 | C-terminal binding protein 2 | 0.0354531 |
| CUX1 | cut-like homeobox 1 | 0.0352918 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0349536 |
| IFI44L | interferon-induced protein 44-like | 0.0339301 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0332074 |
| FMNL2 | formin-like 2 | 0.0330589 |
| PTMA | prothymosin, alpha | 0.03301 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0325865 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0321415 |
| TPI1 | triosephosphate isomerase 1 | 0.0315699 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0313984 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0313782 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0313031 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0310404 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.030997 |
| PKM | pyruvate kinase, muscle | 0.0309517 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0308647 |
| HDAC9 | histone deacetylase 9 | 0.0306749 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0306247 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0305466 |
| HDAC4 | histone deacetylase 4 | 0.0304525 |
| PLAT | plasminogen activator, tissue | 0.03014 |
| AUTS2 | autism susceptibility candidate 2 | 0.0301348 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0298173 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0296966 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0295798 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0295109 |
| FUS | FUS RNA binding protein | 0.0294354 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0292804 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0291946 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0291128 |
| DENND1A | DENN/MADD domain containing 1A | 0.0288771 |
| ENO1 | enolase 1, (alpha) | 0.0286136 |
| CNKSR3 | CNKSR family member 3 | 0.028609 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0282193 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0281105 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0279615 |
| VEGFA | vascular endothelial growth factor A | 0.0278322 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0276758 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0276078 |
| FRMD4A | FERM domain containing 4A | 0.0275848 |
| OGA | O-GlcNAcase | 0.027573 |
| TOB2 | transducer of ERBB2, 2 | 0.0275705 |
| APOD | apolipoprotein D | 0.0273672 |
| TPM3 | tropomyosin 3 | 0.0270005 |
| NAV1 | neuron navigator 1 | 0.0267875 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0267099 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0263565 |
| PRELID2 | PRELI domain containing 2 | 0.0261074 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0257068 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0256836 |
| VIM | vimentin | 0.0256753 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0256131 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0255779 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128674 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0747452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0701955 |
| TXNRD1 | thioredoxin reductase 1 | -0.0668973 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0628839 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0571473 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0565284 |
| TENM1 | teneurin transmembrane protein 1 | -0.0526619 |
| SQSTM1 | sequestosome 1 | -0.0493152 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.047639 |
| FN1 | fibronectin 1 | -0.0467118 |
| MT2A | metallothionein 2A | -0.0465341 |
| SPAG9 | sperm associated antigen 9 | -0.0458473 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0451623 |
| FMN1 | formin 1 | -0.0398188 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0388356 |
| CD44 | CD44 molecule (Indian blood group) | -0.0372964 |
| CLINT1 | clathrin interactor 1 | -0.0372126 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0363074 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.034735 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0345285 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0342784 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0311185 |
| ACTG1 | actin gamma 1 | -0.0306639 |
| FTL | ferritin, light polypeptide | -0.0300832 |
| GOLGA4 | golgin A4 | -0.0286744 |
| TFG | TRK-fused gene | -0.028324 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0280894 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0273579 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0270787 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0264504 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0264422 |
| CLTC | clathrin, heavy chain (Hc) | -0.0255155 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0254833 |
| ANLN | anillin, actin binding protein | -0.0247656 |
| NAV2 | neuron navigator 2 | -0.0242725 |
| SEC24A | SEC24 family member A | -0.0240468 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0239932 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0239323 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0237382 |
| LOC112694756 | uncharaterized LOC112694756 | -0.023233 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0232105 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0216387 |
| ATP13A3 | ATPase type 13A3 | -0.0211381 |
| CALU | calumenin | -0.0208774 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0207828 |
| CANX | calnexin | -0.0207327 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0207156 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0203388 |
| SUCO | SUN domain containing ossification factor | -0.0197345 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0194758 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0193401 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0188423 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0188358 |
| POTEF | POTE ankyrin domain family, member F | -0.0188053 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0187083 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0184326 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0184287 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.018336 |
| RTN4 | reticulon 4 | -0.0182816 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0179162 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0177506 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0177283 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0170761 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.016957 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0168461 |
| USP3 | ubiquitin specific peptidase 3 | -0.0166529 |
| ABI1 | abl-interactor 1 | -0.01662 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0165522 |
| TMEM41B | transmembrane protein 41B | -0.0163916 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0162161 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0161977 |
| ERBIN | erbb2 interacting protein | -0.0161857 |
| FAM13B | family with sequence similarity 13, member B | -0.0161079 |
| FOXJ3 | forkhead box J3 | -0.0160932 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0160402 |
| RLF | rearranged L-myc fusion | -0.0160246 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | -0.0159714 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0159236 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.015881 |
| WASF2 | WAS protein family, member 2 | -0.0158422 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0157175 |
| RHOA | ras homolog family member A | -0.0156319 |
| NUP58 | nucleoporin 58 | -0.0156274 |
| ECT2 | epithelial cell transforming 2 | -0.0156191 |
| PGK1 | phosphoglycerate kinase 1 | -0.0153973 |
| ARF1 | ADP-ribosylation factor 1 | -0.0153941 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0153793 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0152628 |
| UPP1 | uridine phosphorylase 1 | -0.0152569 |
| KIF4A | kinesin family member 4A | -0.0151935 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.0149454 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0149275 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0148429 |
| TPX2 | TPX2, microtubule-associated | -0.0148347 |
| CENPE | centromere protein E, 312kDa | -0.0147913 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0146457 |
| NGLY1 | N-glycanase 1 | -0.0145855 |
| TMEM39A | transmembrane protein 39A | -0.0145717 |
| RPL39 | ribosomal protein L39 | -0.0144961 |
