| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.183804 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.168336 |
| PTMA | prothymosin, alpha | 0.152604 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.144607 |
| RPS6 | ribosomal protein S6 | 0.13292 |
| PKM | pyruvate kinase, muscle | 0.10331 |
| VCL | vinculin | 0.0854076 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.082603 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0774106 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0772825 |
| EZR | ezrin | 0.076353 |
| TMSB4X | thymosin beta 4, X-linked | 0.0742495 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.074166 |
| ANXA1 | annexin A1 | 0.073172 |
| HDAC9 | histone deacetylase 9 | 0.0722036 |
| RPL3 | ribosomal protein L3 | 0.0717872 |
| PDGFC | platelet derived growth factor C | 0.0641973 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0638055 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0629813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0616365 |
| MKI67 | marker of proliferation Ki-67 | 0.0598352 |
| TJP1 | tight junction protein 1 | 0.059327 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.057633 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0568364 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0547883 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0535022 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0510448 |
| RPS8 | ribosomal protein S8 | 0.0503193 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.05023 |
| JMJD1C | jumonji domain containing 1C | 0.0478332 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0475863 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0464466 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.046071 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0453537 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0446918 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0446611 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0433856 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0421349 |
| ENO1 | enolase 1, (alpha) | 0.0419051 |
| CENPF | centromere protein F, 350/400kDa | 0.0411581 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0402273 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0402054 |
| SFTPA2 | surfactant protein A2 | 0.0385672 |
| PYGB | phosphorylase, glycogen; brain | 0.038439 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0382107 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0372337 |
| ECT2 | epithelial cell transforming 2 | 0.0370582 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0369062 |
| EGFR | epidermal growth factor receptor | 0.0365446 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0364807 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0362599 |
| H1-4 | H1.4 linker histone, cluster member | 0.036142 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0358702 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0344186 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.034338 |
| TXNIP | thioredoxin interacting protein | 0.0343306 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0342447 |
| FOXP1 | forkhead box P1 | 0.0341481 |
| MED13 | mediator complex subunit 13 | 0.0336228 |
| YBX1 | Y box binding protein 1 | 0.0333682 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.033319 |
| FNIP1 | folliculin interacting protein 1 | 0.0332321 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0329649 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0329143 |
| SBF2 | SET binding factor 2 | 0.0329127 |
| PGK1 | phosphoglycerate kinase 1 | 0.0327391 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0326178 |
| ZNF608 | zinc finger protein 608 | 0.0323778 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0318091 |
| RPS2 | ribosomal protein S2 | 0.0316946 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0313671 |
| SLMAP | sarcolemma associated protein | 0.0312476 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0307967 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0307376 |
| RPL19 | ribosomal protein L19 | 0.0303657 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0302447 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0301188 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0300856 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0298886 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0295095 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0293225 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0285908 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0283619 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0283499 |
| OGA | O-GlcNAcase | 0.0283199 |
| TXNRD1 | thioredoxin reductase 1 | 0.0282744 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0279005 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0278466 |
| SETD5 | SET domain containing 5 | 0.0275439 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0275242 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.027494 |
| GOLGA4 | golgin A4 | 0.0274626 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0274429 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.027436 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0272984 |
| MED13L | mediator complex subunit 13-like | 0.0271101 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0270747 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0269674 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0268547 |
| ASPH | aspartate beta-hydroxylase | 0.026743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP10 | bone morphogenetic protein 10 | -0.0376604 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.030287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0267655 |
| KIAA1958 | KIAA1958 | -0.0194709 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0183399 |
| RPS24 | ribosomal protein S24 | -0.0180139 |
| NEBL | nebulette | -0.0176919 |
| S100A6 | S100 calcium binding protein A6 | -0.0176236 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0172706 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0169026 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0166972 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0147563 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0140374 |
| RPS13 | ribosomal protein S13 | -0.0139402 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0139132 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.013823 |
| RIGI | RNA sensor RIG-I | -0.0137404 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0131233 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0129261 |
| SESN2 | sestrin 2 | -0.0129241 |
| RPL30 | ribosomal protein L30 | -0.0125386 |
| SEC13 | SEC13 homolog (S. cerevisiae) | -0.0124982 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0123748 |
| TMSB10 | thymosin beta 10 | -0.0119974 |
| HLA-B | major histocompatibility complex, class I, B | -0.0118188 |
| SQSTM1 | sequestosome 1 | -0.0117535 |
| NFIA | nuclear factor I/A | -0.0115176 |
| XBP1 | X-box binding protein 1 | -0.0114691 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0114373 |
| PLSCR1 | phospholipid scramblase 1 | -0.0114179 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0114008 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0112021 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0111915 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.011126 |
| DIAPH2 | diaphanous-related formin 2 | -0.011064 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0109804 |
| FHIT | fragile histidine triad | -0.0108963 |
| NCOA1 | nuclear receptor coactivator 1 | -0.010892 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -0.010739 |
| ENOSF1 | enolase superfamily member 1 | -0.0107303 |
| ACTN4 | actinin, alpha 4 | -0.0106961 |
| RAB2A | RAB2A, member RAS oncogene family | -0.010675 |
| RPLP0 | ribosomal protein, large, P0 | -0.0106424 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0106242 |
| CORIN | corin, serine peptidase | -0.0103611 |
| CRLS1 | cardiolipin synthase 1 | -0.0103425 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0103292 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0102282 |
| AFG1L | AFG1 like ATPase | -0.0102148 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0101992 |
| KPNB1 | karyopherin (importin) beta 1 | -0.010145 |
| MT2A | metallothionein 2A | -0.010046 |
| RASA3 | RAS p21 protein activator 3 | -0.00993846 |
| RPL36A | ribosomal protein L36a | -0.00978195 |
| TRIM14 | tripartite motif containing 14 | -0.00977109 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.00975206 |
| CENATAC | centrosomal AT-AC splicing factor | -0.00972873 |
| ZNF236 | zinc finger protein 236 | -0.00972567 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.00965535 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.00964602 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00962875 |
| ANXA2 | annexin A2 | -0.00962607 |
| AK3 | adenylate kinase 3 | -0.00960445 |
| RNF121 | ring finger protein 121 | -0.00955634 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.00946047 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | -0.0093742 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0093279 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00925828 |
| DCTN4 | dynactin 4 (p62) | -0.00919623 |
| AGO4 | argonaute RISC catalytic component 4 | -0.00918544 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.00902596 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00897953 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.00895066 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | -0.00892295 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0089019 |
| PRELID2 | PRELI domain containing 2 | -0.0088312 |
| RAN | RAN, member RAS oncogene family | -0.00876923 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00876698 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00874876 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.00866059 |
| CCNI | cyclin I | -0.00865764 |
| SENP7 | SUMO1/sentrin specific peptidase 7 | -0.00865462 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.00863645 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00861049 |
| CNTNAP3B | contactin associated protein-like 3B | -0.00859069 |
| H3-3B | H3.3 histone B | -0.0085832 |
| ANK2 | ankyrin 2, neuronal | -0.00855015 |
| FOXN3 | forkhead box N3 | -0.00853739 |
| TEX14 | testis expressed 14 | -0.00851671 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.00847681 |
| PACRGL | PARK2 co-regulated-like | -0.00847077 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.00846584 |
| KLF2 | Kruppel-like factor 2 | -0.00840931 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.00837889 |
| XXYLT1 | xyloside xylosyltransferase 1 | -0.0083691 |
| RAD51B | RAD51 paralog B | -0.00833163 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00830918 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.008281 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | -0.00823562 |
| RPL9 | ribosomal protein L9 | -0.00822004 |
