| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.184875 |
| NDRG1 | N-myc downstream regulated 1 | 0.127575 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.107553 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102916 |
| SFTPA2 | surfactant protein A2 | 0.101395 |
| RPS6 | ribosomal protein S6 | 0.0946372 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0942039 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0917194 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0758335 |
| RPS12 | ribosomal protein S12 | 0.0751495 |
| VEGFA | vascular endothelial growth factor A | 0.0750692 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0728631 |
| HDAC9 | histone deacetylase 9 | 0.0722134 |
| GLIS3 | GLIS family zinc finger 3 | 0.0702861 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0686377 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0657205 |
| ASPH | aspartate beta-hydroxylase | 0.0648414 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0647282 |
| TXNIP | thioredoxin interacting protein | 0.0626024 |
| CD44 | CD44 molecule (Indian blood group) | 0.0595372 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0578412 |
| RPS2 | ribosomal protein S2 | 0.0557756 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0551035 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0550645 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0540784 |
| B2M | beta-2-microglobulin | 0.0533973 |
| DST | dystonin | 0.0531263 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0529592 |
| LDHA | lactate dehydrogenase A | 0.0526461 |
| OPTN | optineurin | 0.0522758 |
| YBX1 | Y box binding protein 1 | 0.0513329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0507928 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0507527 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0502614 |
| GOLGB1 | golgin B1 | 0.0492792 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0488044 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0463908 |
| PCBP2 | poly(rC) binding protein 2 | 0.0447293 |
| ARRDC3 | arrestin domain containing 3 | 0.0426303 |
| TMF1 | TATA element modulatory factor 1 | 0.0424597 |
| TPM3 | tropomyosin 3 | 0.0418977 |
| SQSTM1 | sequestosome 1 | 0.0416824 |
| APP | amyloid beta (A4) precursor protein | 0.0409884 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0406246 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0397927 |
| MSN | moesin | 0.0385202 |
| RND3 | Rho family GTPase 3 | 0.0383746 |
| OGA | O-GlcNAcase | 0.0381571 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0377769 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0376561 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0371678 |
| BICC1 | BicC family RNA binding protein 1 | 0.0361458 |
| PHF3 | PHD finger protein 3 | 0.036034 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0357221 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0351574 |
| MATR3 | matrin 3 | 0.0347661 |
| BRD2 | bromodomain containing 2 | 0.0340906 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0333795 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0331622 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0329993 |
| CANX | calnexin | 0.0327387 |
| USP37 | ubiquitin specific peptidase 37 | 0.0326961 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0323631 |
| RPS8 | ribosomal protein S8 | 0.0322009 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0305272 |
| RPS4X | ribosomal protein S4, X-linked | 0.0303229 |
| SLK | STE20-like kinase | 0.030241 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0291569 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0285122 |
| PHF21A | PHD finger protein 21A | 0.0284719 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0280702 |
| ENO1 | enolase 1, (alpha) | 0.0279735 |
| ANXA1 | annexin A1 | 0.0278047 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0278038 |
| RPL37A | ribosomal protein L37a | 0.0277445 |
| PLS3 | plastin 3 | 0.0276843 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0272462 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0270229 |
| ARFGEF3 | ARFGEF family member 3 | 0.0270057 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0269979 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0269355 |
| RPL11 | ribosomal protein L11 | 0.0268648 |
| GOLGA4 | golgin A4 | 0.0263758 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0260846 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0258422 |
| ZNF292 | zinc finger protein 292 | 0.0253828 |
| AHR | aryl hydrocarbon receptor | 0.0252893 |
| HMGA2 | high mobility group AT-hook 2 | 0.0252032 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0251797 |
| SMAD3 | SMAD family member 3 | 0.0245475 |
| VMP1 | vacuole membrane protein 1 | 0.0245349 |
| RACK1 | receptor for activated C kinase 1 | 0.0243218 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0242803 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0240606 |
| RPS3 | ribosomal protein S3 | 0.0238826 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0237897 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0237723 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0237413 |
| CLU | clusterin | 0.0234939 |
| ZNF608 | zinc finger protein 608 | 0.0234406 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.165759 |
| FRMD4A | FERM domain containing 4A | -0.144081 |
| TMSB10 | thymosin beta 10 | -0.11236 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0987781 |
| IER3 | immediate early response 3 | -0.0784865 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0783148 |
| HLA-B | major histocompatibility complex, class I, B | -0.0713853 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0703011 |
| RPS24 | ribosomal protein S24 | -0.0606809 |
| NAV2 | neuron navigator 2 | -0.0606697 |
| CADM1 | cell adhesion molecule 1 | -0.0598558 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0585966 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0561509 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0553482 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0494897 |
| TPM4 | tropomyosin 4 | -0.0476926 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0467377 |
| EGR1 | early growth response 1 | -0.0458223 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0455711 |
| PDE10A | phosphodiesterase 10A | -0.0454021 |
| PTMA | prothymosin, alpha | -0.0449205 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0424174 |
| ACTG1 | actin gamma 1 | -0.0416812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0413505 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.040567 |
| CTSD | cathepsin D | -0.0398174 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0395203 |
| RPS21 | ribosomal protein S21 | -0.0394349 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0394252 |
| CLIC4 | chloride intracellular channel 4 | -0.0392938 |
| RPL35A | ribosomal protein L35a | -0.0382145 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0377947 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0370938 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0369263 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0368585 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0366731 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0366261 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0363823 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0361058 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356736 |
| TUBB | tubulin, beta class I | -0.0347491 |
| VCL | vinculin | -0.0345439 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0343504 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0326629 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0325248 |
| C3 | complement component 3 | -0.0318163 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0304986 |
| KLHL5 | kelch-like family member 5 | -0.030488 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303054 |
| PALLD | palladin, cytoskeletal associated protein | -0.0300895 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0300817 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0295629 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0295316 |
| WTAP | Wilms tumor 1 associated protein | -0.0294598 |
| GNAS | GNAS complex locus | -0.0292782 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0291888 |
| FNIP1 | folliculin interacting protein 1 | -0.0277911 |
| FLOT1 | flotillin 1 | -0.0273902 |
| DIAPH2 | diaphanous-related formin 2 | -0.0271854 |
| KLHL24 | kelch-like family member 24 | -0.0271349 |
| EGFR | epidermal growth factor receptor | -0.026936 |
| INHBA | inhibin, beta A | -0.0269034 |
| KLF6 | Kruppel-like factor 6 | -0.0266368 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0266274 |
| RPL23 | ribosomal protein L23 | -0.0266027 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0265208 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0263664 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0260416 |
| CLMP | CXADR-like membrane protein | -0.0259363 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0258848 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0253582 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0251758 |
| NAV1 | neuron navigator 1 | -0.0251073 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0247999 |
| KIF4A | kinesin family member 4A | -0.0247543 |
| MIDN | midnolin | -0.0247316 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0245945 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0245335 |
| SMAD2 | SMAD family member 2 | -0.0242423 |
| NABP1 | nucleic acid binding protein 1 | -0.024098 |
| DENND5A | DENN/MADD domain containing 5A | -0.0239652 |
| NF1 | neurofibromin 1 | -0.0236959 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0234354 |
| BNC2 | basonuclin 2 | -0.023228 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0230354 |
| COL1A1 | collagen, type I, alpha 1 | -0.0229777 |
| CBX3 | chromobox homolog 3 | -0.0227701 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.0227297 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0226964 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0225649 |
| PGK1 | phosphoglycerate kinase 1 | -0.0224594 |
| ATP13A3 | ATPase type 13A3 | -0.0223187 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0221809 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0220372 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0219617 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0219409 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0217208 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0212317 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0212066 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0208737 |
