| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM156 | transmembrane protein 156 | 0.173522 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.145171 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.12827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0903055 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0864896 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0842885 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.076114 |
| GOLGA4 | golgin A4 | 0.0732591 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0709377 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.069421 |
| TXNRD1 | thioredoxin reductase 1 | 0.0682983 |
| KLHL5 | kelch-like family member 5 | 0.0682479 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0659974 |
| RPS6 | ribosomal protein S6 | 0.065267 |
| MT2A | metallothionein 2A | 0.0636112 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0633666 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0614289 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0591076 |
| NRP1 | neuropilin 1 | 0.058112 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0569047 |
| JMJD1C | jumonji domain containing 1C | 0.0515236 |
| VIM | vimentin | 0.0508255 |
| SFTPA2 | surfactant protein A2 | 0.0506939 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0498612 |
| B2M | beta-2-microglobulin | 0.0495067 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0480801 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0473263 |
| ERBIN | erbb2 interacting protein | 0.0471679 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0460273 |
| DST | dystonin | 0.0455651 |
| PTMA | prothymosin, alpha | 0.0449828 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0448022 |
| TPM3 | tropomyosin 3 | 0.0442668 |
| RACK1 | receptor for activated C kinase 1 | 0.0434545 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0426265 |
| DENND5B | DENN/MADD domain containing 5B | 0.0421041 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0411223 |
| IL6ST | interleukin 6 signal transducer | 0.0409879 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0407996 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0403429 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0401902 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.039969 |
| MKI67 | marker of proliferation Ki-67 | 0.0399194 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0399165 |
| STC2 | stanniocalcin 2 | 0.0398563 |
| NTN4 | netrin 4 | 0.0388653 |
| CENPF | centromere protein F, 350/400kDa | 0.0384825 |
| VEGFA | vascular endothelial growth factor A | 0.0383589 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0377461 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0375717 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0374566 |
| SVIL | supervillin | 0.0372877 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0372316 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0371129 |
| RPL37A | ribosomal protein L37a | 0.0370049 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0364699 |
| RNF145 | ring finger protein 145 | 0.0361526 |
| RPS12 | ribosomal protein S12 | 0.0361208 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0359707 |
| FTL | ferritin, light polypeptide | 0.0358318 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.03578 |
| CDCP1 | CUB domain containing protein 1 | 0.0355605 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352253 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0352149 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0348493 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0346734 |
| PARD3 | par-3 family cell polarity regulator | 0.0345213 |
| FNBP1 | formin binding protein 1 | 0.034382 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0340973 |
| EZR | ezrin | 0.0339859 |
| RPL26 | ribosomal protein L26 | 0.0339844 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.033779 |
| MAP1B | microtubule-associated protein 1B | 0.0335138 |
| PDS5A | PDS5 cohesin associated factor A | 0.0331368 |
| S100A6 | S100 calcium binding protein A6 | 0.0329947 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0328828 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0325688 |
| DOCK5 | dedicator of cytokinesis 5 | 0.032533 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0324439 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0321465 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0320035 |
| DSTN | destrin (actin depolymerizing factor) | 0.031663 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.031502 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0312263 |
| SRPK2 | SRSF protein kinase 2 | 0.0311012 |
| RPS8 | ribosomal protein S8 | 0.0310619 |
| KIF5B | kinesin family member 5B | 0.0310211 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0308931 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0304059 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0300485 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0299518 |
| RPS27 | ribosomal protein S27 | 0.0294983 |
| YBX3 | Y box binding protein 3 | 0.0294595 |
| RPLP1 | ribosomal protein, large, P1 | 0.0294457 |
| RPS25 | ribosomal protein S25 | 0.02935 |
| AHR | aryl hydrocarbon receptor | 0.0293245 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0291819 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0291396 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0289263 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0288658 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.271842 |
| NRG1 | neuregulin 1 | -0.235779 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.152411 |
| HMGA2 | high mobility group AT-hook 2 | -0.101581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0822844 |
| AEBP2 | AE binding protein 2 | -0.0815066 |
| VCL | vinculin | -0.0809668 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0780509 |
| SQSTM1 | sequestosome 1 | -0.0731265 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0702149 |
| INTS6 | integrator complex subunit 6 | -0.0698766 |
| GLIS3 | GLIS family zinc finger 3 | -0.056533 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0536976 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0522536 |
| LRRC23 | leucine rich repeat containing 23 | -0.0512675 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.047868 |
| FAM20C | family with sequence similarity 20, member C | -0.0445206 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0439928 |
| TUFT1 | tuftelin 1 | -0.041462 |
| CADM1 | cell adhesion molecule 1 | -0.036693 |
| PRELID2 | PRELI domain containing 2 | -0.0350405 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0348229 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0345798 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0343535 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0340605 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0330745 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327068 |
| LOX | lysyl oxidase | -0.032582 |
| DPYD | dihydropyrimidine dehydrogenase | -0.031971 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0315678 |
| TENM4 | teneurin transmembrane protein 4 | -0.0312024 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0310492 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0302169 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0296593 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295879 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0279689 |
| FLNA | filamin A, alpha | -0.027908 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0272607 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.027217 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0272159 |
| RAD51B | RAD51 paralog B | -0.0268676 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0267601 |
| HPCAL1 | hippocalcin-like 1 | -0.0266029 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0263511 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0249147 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0248174 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0246008 |
| TGFB1 | transforming growth factor, beta 1 | -0.0244935 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0243192 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0237034 |
| LOXL2 | lysyl oxidase-like 2 | -0.0236194 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235684 |
| TGFA | transforming growth factor, alpha | -0.0235204 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0234748 |
| ADAM8 | ADAM metallopeptidase domain 8 | -0.0231271 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0226949 |
| TMSB10 | thymosin beta 10 | -0.0225187 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0223278 |
| POU2F2 | POU class 2 homeobox 2 | -0.0222084 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0219763 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0219251 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.0215736 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0214189 |
| CCDC138 | coiled-coil domain containing 138 | -0.0213686 |
| NABP1 | nucleic acid binding protein 1 | -0.0213391 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0210858 |
| GOLGA7B | golgin A7 family, member B | -0.0206938 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0206377 |
| HDLBP | high density lipoprotein binding protein | -0.0206334 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0206156 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0206114 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0205226 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0202101 |
| GLUL | glutamate-ammonia ligase | -0.0198077 |
| ACTN4 | actinin, alpha 4 | -0.0197075 |
| NAV1 | neuron navigator 1 | -0.0193887 |
| WDR1 | WD repeat domain 1 | -0.0193216 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0187768 |
| ITGB4 | integrin, beta 4 | -0.0187294 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0186752 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0185177 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0185018 |
| MCL1 | myeloid cell leukemia 1 | -0.018487 |
| FERMT2 | fermitin family member 2 | -0.0184634 |
| RNF220 | ring finger protein 220 | -0.0184105 |
| CUX1 | cut-like homeobox 1 | -0.0182256 |
| FGF18 | fibroblast growth factor 18 | -0.0179883 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0179806 |
| ACTG1 | actin gamma 1 | -0.0178476 |
| BAIAP2 | BAI1-associated protein 2 | -0.0178372 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0177563 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0177342 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0176295 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0173322 |
| CTSD | cathepsin D | -0.0172836 |
| FHIT | fragile histidine triad | -0.017233 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0171559 |
| TTC23L | tetratricopeptide repeat domain 23-like | -0.0171505 |
| SYT1 | synaptotagmin I | -0.0171304 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0169597 |
