| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.101352 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.100355 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0950768 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0871151 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0818256 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0779594 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0712779 |
| INTS6 | integrator complex subunit 6 | 0.068883 |
| TMSB10 | thymosin beta 10 | 0.0683288 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0620399 |
| RPL37A | ribosomal protein L37a | 0.0603967 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0602164 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0587316 |
| EGFR | epidermal growth factor receptor | 0.0575499 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0567344 |
| EHBP1 | EH domain binding protein 1 | 0.0559139 |
| RPS27A | ribosomal protein S27a | 0.054532 |
| SMAD3 | SMAD family member 3 | 0.0523474 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0513508 |
| VCL | vinculin | 0.0505001 |
| RPS12 | ribosomal protein S12 | 0.0503144 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0502612 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0492721 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0487604 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0486949 |
| MYO1E | myosin IE | 0.0484685 |
| RPS21 | ribosomal protein S21 | 0.0466345 |
| BPTF | bromodomain PHD finger transcription factor | 0.046517 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0463724 |
| BCL2L1 | BCL2-like 1 | 0.046001 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0459368 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0457101 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0454238 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0449893 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0445694 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.043765 |
| CDK13 | cyclin-dependent kinase 13 | 0.0434398 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0431339 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0419844 |
| CTBP2 | C-terminal binding protein 2 | 0.0410387 |
| GOLGB1 | golgin B1 | 0.0404775 |
| CADPS | Ca++-dependent secretion activator | 0.0401394 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0400114 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0394187 |
| RAD51B | RAD51 paralog B | 0.0389413 |
| RPS19 | ribosomal protein S19 | 0.0383702 |
| NEBL | nebulette | 0.0382738 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0381579 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0379418 |
| SETX | senataxin | 0.0378463 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0372685 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0368113 |
| ATXN1 | ataxin 1 | 0.0366146 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0365319 |
| NRP1 | neuropilin 1 | 0.0365184 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.036459 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0363286 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0359659 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0356545 |
| ASPH | aspartate beta-hydroxylase | 0.0353891 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0352634 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0346173 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0342015 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0338535 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0337217 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0337179 |
| UBC | ubiquitin C | 0.0336329 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0334796 |
| CUX1 | cut-like homeobox 1 | 0.0334646 |
| EZR | ezrin | 0.0334181 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0334077 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0328406 |
| RPS8 | ribosomal protein S8 | 0.0326961 |
| FAM107B | family with sequence similarity 107, member B | 0.0326473 |
| RPS4X | ribosomal protein S4, X-linked | 0.0325932 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0324425 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0322934 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0322495 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0318791 |
| RPL31 | ribosomal protein L31 | 0.0315302 |
| SMYD3 | SET and MYND domain containing 3 | 0.031313 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0311657 |
| RPS3 | ribosomal protein S3 | 0.0311565 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0311075 |
| RPL23 | ribosomal protein L23 | 0.0310892 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.030968 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0306057 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0304948 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0304705 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0303335 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0301484 |
| ATXN2 | ataxin 2 | 0.0301099 |
| AHNAK | AHNAK nucleoprotein | 0.0299924 |
| RUNX1 | runt-related transcription factor 1 | 0.0299852 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.029774 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0297167 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0296547 |
| RPS17 | ribosomal protein S17 | 0.0295912 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0294411 |
| YAP1 | Yes-associated protein 1 | 0.0294273 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.112387 |
| H1-0 | H1.0 linker histone | -0.0930952 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0815932 |
| RBM39 | RNA binding motif protein 39 | -0.0756724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0719172 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0716922 |
| MATR3 | matrin 3 | -0.070648 |
| PTMA | prothymosin, alpha | -0.0700058 |
| USP3 | ubiquitin specific peptidase 3 | -0.0626369 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0621476 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0598635 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0590237 |
| TMEM123 | transmembrane protein 123 | -0.0584655 |
| NCKAP1 | NCK-associated protein 1 | -0.056002 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0550327 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0541158 |
| ZNF292 | zinc finger protein 292 | -0.0534278 |
| GOLGA4 | golgin A4 | -0.0531508 |
| SPAG9 | sperm associated antigen 9 | -0.0512082 |
| CANX | calnexin | -0.0506542 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0500516 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.049446 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0489665 |
| RYBP | RING1 and YY1 binding protein | -0.0482933 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0474927 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0469948 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0461171 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0458617 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0453698 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0450337 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0449791 |
| TFG | TRK-fused gene | -0.044548 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0442421 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0437289 |
| XPO1 | exportin 1 | -0.0431144 |
| FMR1 | fragile X mental retardation 1 | -0.0419518 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0416077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0406901 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0400159 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0400097 |
| SNX9 | sorting nexin 9 | -0.0399537 |
| MACC1 | metastasis associated in colon cancer 1 | -0.03995 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0398633 |
| SEPTIN7 | septin 7 | -0.0396356 |
| CLINT1 | clathrin interactor 1 | -0.0393896 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0389792 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0383593 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0383116 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0380424 |
| RHEB | Ras homolog enriched in brain | -0.0376544 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.037522 |
| EPCAM | epithelial cell adhesion molecule | -0.0365685 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0356055 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.035602 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0348236 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0346459 |
| DSPP | dentin sialophosphoprotein | -0.0343019 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0341852 |
| NEK7 | NIMA-related kinase 7 | -0.0341284 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.033716 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0335745 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0334042 |
| CCND1 | cyclin D1 | -0.0333882 |
| SQSTM1 | sequestosome 1 | -0.0332836 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.033233 |
| SUCO | SUN domain containing ossification factor | -0.0326001 |
| H3-3B | H3.3 histone B | -0.0322047 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0320117 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0315136 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0313005 |
| AFDN | afadin, adherens junction formation factor | -0.0308446 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0306963 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0306399 |
| HBP1 | HMG-box transcription factor 1 | -0.0304812 |
| TMSB4X | thymosin beta 4, X-linked | -0.0300777 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0295458 |
| CHMP2B | charged multivesicular body protein 2B | -0.0295219 |
| SF1 | splicing factor 1 | -0.0294889 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0294714 |
| IPO7 | importin 7 | -0.0294512 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0294329 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0293893 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0292985 |
| MTMR3 | myotubularin related protein 3 | -0.0291699 |
| UBQLN1 | ubiquilin 1 | -0.0290952 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0289197 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.028558 |
| MKI67 | marker of proliferation Ki-67 | -0.0285463 |
| CXADR | coxsackie virus and adenovirus receptor | -0.028466 |
| RBM33 | RNA binding motif protein 33 | -0.0283653 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0281601 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0278158 |
| HMGB2 | high mobility group box 2 | -0.0277883 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0277501 |
| OXR1 | oxidation resistance 1 | -0.0277218 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0276483 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0275724 |
| PERP | PERP, TP53 apoptosis effector | -0.0275185 |
| GPSM2 | G-protein signaling modulator 2 | -0.0274704 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0274181 |
