| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pasireotide (acetate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.182667 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.169993 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.128684 |
| VCL | vinculin | 0.124618 |
| RPS6 | ribosomal protein S6 | 0.122371 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.106294 |
| ASPH | aspartate beta-hydroxylase | 0.102954 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0934495 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0901754 |
| DST | dystonin | 0.0857581 |
| DSPP | dentin sialophosphoprotein | 0.0831135 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0817107 |
| AHNAK | AHNAK nucleoprotein | 0.0816821 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0799024 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0739181 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0724835 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.072405 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0688516 |
| NAV2 | neuron navigator 2 | 0.0687482 |
| YAP1 | Yes-associated protein 1 | 0.0617253 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.059594 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0571189 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0562449 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0554146 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.054048 |
| MT2A | metallothionein 2A | 0.0519382 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0499294 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0488837 |
| YBX1 | Y box binding protein 1 | 0.0488459 |
| UBAP2 | ubiquitin associated protein 2 | 0.0487759 |
| FRMD5 | FERM domain containing 5 | 0.0485884 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0485094 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0468085 |
| RPL3 | ribosomal protein L3 | 0.0461464 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0459559 |
| RCOR1 | REST corepressor 1 | 0.0449612 |
| SFPQ | splicing factor proline/glutamine-rich | 0.044756 |
| MKI67 | marker of proliferation Ki-67 | 0.044378 |
| RPS12 | ribosomal protein S12 | 0.0439822 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.04374 |
| TNS3 | tensin 3 | 0.0434362 |
| SMAD3 | SMAD family member 3 | 0.0421219 |
| GOLGB1 | golgin B1 | 0.0416323 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0407577 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0405025 |
| CDH13 | cadherin 13 | 0.0404589 |
| LMO7 | LIM domain 7 | 0.0402313 |
| VMP1 | vacuole membrane protein 1 | 0.0399227 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.039637 |
| BRD2 | bromodomain containing 2 | 0.0389699 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0381691 |
| TMSB10 | thymosin beta 10 | 0.0381387 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0381138 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0369687 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.03668 |
| RPL23 | ribosomal protein L23 | 0.0360062 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.035559 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0354552 |
| RPL19 | ribosomal protein L19 | 0.0352977 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0352799 |
| MSN | moesin | 0.0351141 |
| SYT1 | synaptotagmin I | 0.0349897 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.034622 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0344721 |
| TPM3 | tropomyosin 3 | 0.0343507 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0340003 |
| RPS19 | ribosomal protein S19 | 0.0339487 |
| WWOX | WW domain containing oxidoreductase | 0.0337402 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0327767 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0327306 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0327205 |
| CDK13 | cyclin-dependent kinase 13 | 0.0326407 |
| CENPF | centromere protein F, 350/400kDa | 0.0322897 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0321899 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0317131 |
| ANO6 | anoctamin 6 | 0.0316517 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0310206 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0308755 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0308184 |
| ATXN1 | ataxin 1 | 0.0306818 |
| RPS8 | ribosomal protein S8 | 0.0303166 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0302539 |
| PRKCA | protein kinase C, alpha | 0.0301395 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0297937 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0296831 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0295866 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0294525 |
| PLEC | plectin | 0.0288789 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0285775 |
| ERBIN | erbb2 interacting protein | 0.0284894 |
| MCL1 | myeloid cell leukemia 1 | 0.0284709 |
| RCC1 | regulator of chromosome condensation 1 | 0.028188 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0280016 |
| EHBP1 | EH domain binding protein 1 | 0.0277378 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0274817 |
| AEBP2 | AE binding protein 2 | 0.0274346 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0272754 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269674 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0269066 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.026865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0623217 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0502833 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0424352 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0417891 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0413107 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0412522 |
| ITGB4 | integrin, beta 4 | -0.0384744 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0375333 |
| AOPEP | aminopeptidase O (putative) | -0.0373922 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0353207 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0352854 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.034733 |
| OXR1 | oxidation resistance 1 | -0.0344246 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0342875 |
| HMGA1 | high mobility group AT-hook 1 | -0.0308668 |
| PERP | PERP, TP53 apoptosis effector | -0.0301263 |
| TMEM41B | transmembrane protein 41B | -0.0300439 |
| ACTG1 | actin gamma 1 | -0.0295549 |
| ANLN | anillin, actin binding protein | -0.0293468 |
| ABLIM1 | actin binding LIM protein 1 | -0.0291387 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0288374 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0283641 |
| USP3 | ubiquitin specific peptidase 3 | -0.027642 |
| RPL35A | ribosomal protein L35a | -0.0275283 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0273031 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272896 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0272173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0269633 |
| CCND1 | cyclin D1 | -0.0266818 |
| TUBA1B | tubulin, alpha 1b | -0.0266531 |
| RPLP0 | ribosomal protein, large, P0 | -0.0264719 |
| ZNF292 | zinc finger protein 292 | -0.0263692 |
| ANXA2 | annexin A2 | -0.0263041 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0254679 |
| TMEM123 | transmembrane protein 123 | -0.02544 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0251324 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0249522 |
| NF1 | neurofibromin 1 | -0.0249505 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0243846 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0236913 |
| R3HDM1 | R3H domain containing 1 | -0.0234472 |
| THOC2 | THO complex 2 | -0.0231855 |
| DIAPH3 | diaphanous-related formin 3 | -0.0231187 |
| RUNX1 | runt-related transcription factor 1 | -0.0230959 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224148 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0223014 |
| HMGB1 | high mobility group box 1 | -0.0221565 |
| ARF1 | ADP-ribosylation factor 1 | -0.0221532 |
| XPO7 | exportin 7 | -0.021954 |
| RLF | rearranged L-myc fusion | -0.0218596 |
| SNX9 | sorting nexin 9 | -0.0217288 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0215346 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0215075 |
| YEATS2 | YEATS domain containing 2 | -0.0212588 |
| RPL39 | ribosomal protein L39 | -0.0211504 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0208899 |
| CCDC82 | coiled-coil domain containing 82 | -0.0204817 |
| RPS24 | ribosomal protein S24 | -0.0202492 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0202431 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0201565 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0199498 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0196633 |
| ZFR | zinc finger RNA binding protein | -0.0194345 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0193899 |
| RPLP1 | ribosomal protein, large, P1 | -0.019088 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0190476 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0189971 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0186755 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0186704 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.018664 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0186545 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0185451 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0184735 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0184311 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.01826 |
| ITGB5 | integrin, beta 5 | -0.0182512 |
| RAD21 | RAD21 homolog (S. pombe) | -0.018208 |
| XPO1 | exportin 1 | -0.0181797 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0181603 |
| RPS16 | ribosomal protein S16 | -0.0181432 |
| ARF4 | ADP-ribosylation factor 4 | -0.0178622 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0178538 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0176843 |
| WDR45B | WD repeat domain 45B | -0.0176164 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0175063 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0170209 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0167275 |
| TUBB | tubulin, beta class I | -0.0166672 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0164688 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0164614 |
| TNS4 | tensin 4 | -0.0164327 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0163702 |
| PDE8A | phosphodiesterase 8A | -0.0162946 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0162718 |
| NEBL | nebulette | -0.0162717 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0162591 |
| MORF4L2 | mortality factor 4 like 2 | -0.0162584 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0162368 |
| ATXN2L | ataxin 2-like | -0.0161827 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0161258 |
