| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pasireotide (acetate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pasireotide (acetate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.25781 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.152181 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.145279 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0939085 |
| RPS6 | ribosomal protein S6 | 0.0854826 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0754861 |
| DSPP | dentin sialophosphoprotein | 0.0741054 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0715418 |
| VEGFA | vascular endothelial growth factor A | 0.0707008 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0685411 |
| HMGA2 | high mobility group AT-hook 2 | 0.0674439 |
| DST | dystonin | 0.0638832 |
| FTL | ferritin, light polypeptide | 0.0625946 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.054052 |
| GOLGB1 | golgin B1 | 0.0537721 |
| GOLGA4 | golgin A4 | 0.0503336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0487917 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0486713 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0473284 |
| RUNX1 | runt-related transcription factor 1 | 0.0469254 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0466696 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.04557 |
| COL1A2 | collagen, type I, alpha 2 | 0.0446919 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0443082 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0429899 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0428752 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0428744 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0427347 |
| MSN | moesin | 0.0421561 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0412353 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0407563 |
| RPL35A | ribosomal protein L35a | 0.0398464 |
| ERBIN | erbb2 interacting protein | 0.0396871 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0396248 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0395262 |
| PRELID2 | PRELI domain containing 2 | 0.039356 |
| AHNAK | AHNAK nucleoprotein | 0.0392317 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0383972 |
| RPL19 | ribosomal protein L19 | 0.0375037 |
| RPL23 | ribosomal protein L23 | 0.0366756 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0366465 |
| SETD5 | SET domain containing 5 | 0.036512 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0357263 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0352562 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0351851 |
| RPL12 | ribosomal protein L12 | 0.0348505 |
| PKM | pyruvate kinase, muscle | 0.0347706 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.034761 |
| UBC | ubiquitin C | 0.0340695 |
| INTS6 | integrator complex subunit 6 | 0.0338169 |
| MCL1 | myeloid cell leukemia 1 | 0.0333521 |
| RPL3 | ribosomal protein L3 | 0.0319446 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0319282 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0312975 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0311772 |
| RPL37A | ribosomal protein L37a | 0.0309313 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.030549 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0300952 |
| TMF1 | TATA element modulatory factor 1 | 0.0298444 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.029619 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.029432 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0292027 |
| RPL31 | ribosomal protein L31 | 0.029053 |
| HELZ | helicase with zinc finger | 0.0287485 |
| PTK2 | protein tyrosine kinase 2 | 0.0286327 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0283866 |
| FMNL2 | formin-like 2 | 0.028306 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0283053 |
| TPM3 | tropomyosin 3 | 0.0282724 |
| VCL | vinculin | 0.028139 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0280673 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0280651 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0280445 |
| SFTPA2 | surfactant protein A2 | 0.0279694 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0278894 |
| RPLP1 | ribosomal protein, large, P1 | 0.0278718 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0277454 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0271137 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.026953 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0268789 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0266719 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0266466 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0264157 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0262491 |
| CCDC88A | coiled-coil domain containing 88A | 0.026238 |
| RPS29 | ribosomal protein S29 | 0.0260646 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.026046 |
| CLIC4 | chloride intracellular channel 4 | 0.0260259 |
| EFNA5 | ephrin-A5 | 0.0259325 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0259078 |
| RPL11 | ribosomal protein L11 | 0.025889 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0258336 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257893 |
| FN1 | fibronectin 1 | 0.0257311 |
| RPS16 | ribosomal protein S16 | 0.0256356 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0254618 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0253467 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0252822 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0252228 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0252224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.127454 |
| VIM | vimentin | -0.124442 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.11257 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109207 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.10619 |
| OXR1 | oxidation resistance 1 | -0.0968825 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0924196 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0912798 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0731411 |
| MMP1 | matrix metallopeptidase 1 | -0.0703158 |
| GLIS3 | GLIS family zinc finger 3 | -0.057022 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0546489 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0514958 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.050721 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0487217 |
| MT2A | metallothionein 2A | -0.0480802 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0471777 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0453691 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0428125 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0423949 |
| CDH13 | cadherin 13 | -0.0422532 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0405073 |
| DIAPH2 | diaphanous-related formin 2 | -0.0393864 |
| OSMR | oncostatin M receptor | -0.0384589 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0384058 |
| CCDC102B | coiled-coil domain containing 102B | -0.037132 |
| ITGA1 | integrin, alpha 1 | -0.0360607 |
| COL1A1 | collagen, type I, alpha 1 | -0.0354956 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0346562 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0338645 |
| ATP13A3 | ATPase type 13A3 | -0.0326201 |
| PDE8A | phosphodiesterase 8A | -0.0320294 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0320062 |
| TRAM2 | translocation associated membrane protein 2 | -0.030776 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0300701 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0295513 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0293745 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0289708 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0289532 |
| PCBP3 | poly(rC) binding protein 3 | -0.0288745 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0283785 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0282943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0282313 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0280896 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0275001 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.027313 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0269077 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0268348 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0263709 |
| NCKAP5 | NCK-associated protein 5 | -0.0258612 |
| KIAA1549L | KIAA1549-like | -0.0258264 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.025494 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0254465 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0252218 |
| PRSS23 | protease, serine, 23 | -0.0251868 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0244051 |
| PLPP3 | phospholipid phosphatase 3 | -0.0243764 |
| RAI14 | retinoic acid induced 14 | -0.0242653 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0239281 |
| RASAL2 | RAS protein activator like 2 | -0.0239066 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0238977 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0235306 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0231422 |
| COL5A1 | collagen, type V, alpha 1 | -0.0231313 |
| TMSB10 | thymosin beta 10 | -0.0226384 |
| PRRX1 | paired related homeobox 1 | -0.0225052 |
| FSTL1 | follistatin-like 1 | -0.0224605 |
| FAM13A | family with sequence similarity 13, member A | -0.0223509 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0220866 |
| HLA-E | major histocompatibility complex, class I, E | -0.0219934 |
| GANAB | glucosidase, alpha; neutral AB | -0.0219617 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0218467 |
| FBN1 | fibrillin 1 | -0.0218032 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0214836 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0204411 |
| ARHGAP10 | Rho GTPase activating protein 10 | -0.0204048 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0203215 |
| MMP12 | matrix metallopeptidase 12 | -0.019899 |
| INSIG1 | insulin induced gene 1 | -0.0198419 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0195508 |
| SRGN | serglycin | -0.019356 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0193081 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0190003 |
| TMEM263 | transmembrane protein 263 | -0.0188894 |
| THBS2 | thrombospondin 2 | -0.0187761 |
| CANX | calnexin | -0.0186306 |
| LOX | lysyl oxidase | -0.0184373 |
| EHD2 | EH-domain containing 2 | -0.0179043 |
| ARF1 | ADP-ribosylation factor 1 | -0.0178917 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.017837 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0176163 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.017475 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0174733 |
| CAVIN1 | caveolae associated protein 1 | -0.0173474 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.017008 |
| TMSB4X | thymosin beta 4, X-linked | -0.0167967 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0167576 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0165924 |
| H3-3B | H3.3 histone B | -0.0164807 |
| SEC24D | SEC24 family member D | -0.0163417 |
