Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C4050407
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Genes

69 genes associated with the disease Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACR acrosin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BPI bactericidal/permeability-increasing protein
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD226 CD226 molecule
CD28 CD28 molecule
CDK6 cyclin-dependent kinase 6
CEL carboxyl ester lipase
CIITA class II, major histocompatibility complex, transactivator
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DEFB1 defensin, beta 1
DEFB104A defensin, beta 104A
DEFB104B defensin, beta 104B
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DPP4 dipeptidyl-peptidase 4
ELANE elastase, neutrophil expressed
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLNB filamin B, beta
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
HLA-A major histocompatibility complex, class I, A
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNG interferon, gamma
IL10 interleukin 10
IL1B interleukin 1, beta
IL2 interleukin 2
IL4 interleukin 4
IRF5 interferon regulatory factor 5
KRT20 keratin 20, type I
KRT3 keratin 3, type II
LEPR leptin receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIP major intrinsic protein of lens fiber
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MPO myeloperoxidase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NBN nibrin
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NXF1 nuclear RNA export factor 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PDCD1 programmed cell death 1
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RBM45 RNA binding motif protein 45
RING1 ring finger protein 1
RXRB retinoid X receptor, beta
S100A7 S100 calcium binding protein A7
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP53 tumor protein p53
TST thiosulfate sulfurtransferase (rhodanese)
USO1 USO1 vesicle transport factor
XCL1 chemokine (C motif) ligand 1