Pauciarticular juvenile arthritis_Peripheral blood mononuclear cell_GSE1402 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1402
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Genes

600 genes differentially expressed during Pauciarticular juvenile arthritis_Peripheral blood mononuclear cell_GSE1402 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 3.36297
PCYT1B phosphate cytidylyltransferase 1, choline, beta 3.22798
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 3.03229
IGHMBP2 immunoglobulin mu binding protein 2 3.00935
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.98418
LOR loricrin 2.95436
SREBF1 sterol regulatory element binding transcription factor 1 2.92328
PRSS22 protease, serine, 22 2.74737
SSTR3 somatostatin receptor 3 2.74048
MVK mevalonate kinase 2.67517
GPR161 G protein-coupled receptor 161 2.67367
NCSTN nicastrin 2.63052
CLDN4 claudin 4 2.62866
HAP1 huntingtin-associated protein 1 2.61407
PARD6A par-6 family cell polarity regulator alpha 2.60025
NOVA2 neuro-oncological ventral antigen 2 2.56954
EPOR erythropoietin receptor 2.55057
NBL1 neuroblastoma 1, DAN family BMP antagonist 2.50336
MLN motilin 2.4983
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.47318
JAG2 jagged 2 2.45836
RREB1 ras responsive element binding protein 1 2.45447
GPR35 G protein-coupled receptor 35 2.42179
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.39932
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.39241
MTX1 metaxin 1 2.36894
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.36613
SPEF1 sperm flagellar 1 2.34677
FAT2 FAT atypical cadherin 2 2.33556
KRT13 keratin 13, type I 2.32161
IGFBP1 insulin-like growth factor binding protein 1 2.28619
MFSD10 major facilitator superfamily domain containing 10 2.25396
FBLN1 fibulin 1 2.2423
C20ORF194 chromosome 20 open reading frame 194 2.23877
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.22868
INHA inhibin, alpha 2.22333
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.21635
GGT5 gamma-glutamyltransferase 5 2.19321
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.19022
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.16189
SLMO1 slowmo homolog 1 (Drosophila) 2.15723
LBP lipopolysaccharide binding protein 2.14999
HYAL2 hyaluronoglucosaminidase 2 2.14011
NF2 neurofibromin 2 (merlin) 2.1365
ZFP36L1 ZFP36 ring finger protein-like 1 2.13365
OXA1L oxidase (cytochrome c) assembly 1-like 2.1291
P4HB prolyl 4-hydroxylase, beta polypeptide 2.12893
FGF18 fibroblast growth factor 18 2.12247
PLD2 phospholipase D2 2.10647
ERCC4 excision repair cross-complementation group 4 2.1054
IGSF9B immunoglobulin superfamily, member 9B 2.09786
CYB5A cytochrome b5 type A (microsomal) 2.09731
ARF5 ADP-ribosylation factor 5 2.09664
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.08032
ADD2 adducin 2 (beta) 2.0762
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.07402
SIM2 single-minded family bHLH transcription factor 2 2.07335
ECE2 endothelin converting enzyme 2 2.06962
SPINK1 serine peptidase inhibitor, Kazal type 1 2.06005
PRAMEF12 PRAME family member 12 2.05784
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.04369
ZC3H3 zinc finger CCCH-type containing 3 2.04316
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.04229
EDA ectodysplasin A 2.04159
HPN hepsin 2.04109
KCTD7 potassium channel tetramerization domain containing 7 2.04089
ACACB acetyl-CoA carboxylase beta 2.0396
HEXIM1 hexamethylene bis-acetamide inducible 1 2.0372
CKB creatine kinase, brain 2.03455
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.03268
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2.0201
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 2.01629
SRRT serrate, RNA effector molecule 2.00695
GLE1 GLE1 RNA export mediator 2.00431
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 2.00431
SSTR5 somatostatin receptor 5 1.99878
FDXR ferredoxin reductase 1.99714
GALNS galactosamine (N-acetyl)-6-sulfatase 1.99607
MT1H metallothionein 1H 1.99601
TP53I11 tumor protein p53 inducible protein 11 1.98808
C19ORF26 chromosome 19 open reading frame 26 1.98439
MFAP2 microfibrillar-associated protein 2 1.98245
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 1.98078
GLUL glutamate-ammonia ligase 1.98066
RPS17 ribosomal protein S17 1.97881
OR7E12P olfactory receptor, family 7, subfamily E, member 12 pseudogene 1.97799
SPTB spectrin, beta, erythrocytic 1.97677
NEUROD2 neuronal differentiation 2 1.97441
BCAM basal cell adhesion molecule (Lutheran blood group) 1.97269
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 1.97175
TM4SF5 transmembrane 4 L six family member 5 1.97165
ZNF592 zinc finger protein 592 1.97077
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 1.9704
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.96861
RPS27A ribosomal protein S27a 1.96077
DAO D-amino-acid oxidase 1.95861
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.95559
SOCS3 suppressor of cytokine signaling 3 1.95453
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 1.95263
PDLIM7 PDZ and LIM domain 7 (enigma) 1.95133
LHB luteinizing hormone beta polypeptide 1.94622
GIGYF2 GRB10 interacting GYF protein 2 1.94573
CSF3 colony stimulating factor 3 (granulocyte) 1.94434
LYPD3 LY6/PLAUR domain containing 3 1.93721
PAX6 paired box 6 1.93713
DHCR7 7-dehydrocholesterol reductase 1.91792
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.91612
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 1.91379
MT4 metallothionein 4 1.90816
FNTB farnesyltransferase, CAAX box, beta 1.90427
CRAT carnitine O-acetyltransferase 1.90268
CDC45 cell division cycle 45 1.89953
AMBP alpha-1-microglobulin/bikunin precursor 1.8933
NTSR2 neurotensin receptor 2 1.88587
CUL2 cullin 2 1.88522
MAN2A2 mannosidase, alpha, class 2A, member 2 1.88401
ST5 suppression of tumorigenicity 5 1.88391
STARD5 StAR-related lipid transfer (START) domain containing 5 1.88092
AP3M2 adaptor-related protein complex 3, mu 2 subunit 1.87892
NPPA natriuretic peptide A 1.87405
MSC musculin 1.87356
E2F1 E2F transcription factor 1 1.87355
EIF4E eukaryotic translation initiation factor 4E 1.86426
IFNW1 interferon, omega 1 1.86269
KLHL35 kelch-like family member 35 1.85377
CRHR2 corticotropin releasing hormone receptor 2 1.84283
CPZ carboxypeptidase Z 1.8382
ADRA2A adrenoceptor alpha 2A 1.82556
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 1.82382
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.81682
NECAB3 N-terminal EF-hand calcium binding protein 3 1.8061
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.80572
LPO lactoperoxidase 1.80493
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 1.80017
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.79778
COL6A1 collagen, type VI, alpha 1 1.79369
EIF3K eukaryotic translation initiation factor 3, subunit K 1.79297
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 1.79296
SNN stannin 1.79288
TRIP6 thyroid hormone receptor interactor 6 1.78831
ENSA endosulfine alpha 1.7823
NUP93 nucleoporin 93kDa 1.78137
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.77927
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 1.77864
UNC5B unc-5 homolog B (C. elegans) 1.77192
MASP2 mannan-binding lectin serine peptidase 2 1.77076
CD34 CD34 molecule 1.76626
RANBP2 RAN binding protein 2 1.76574
LTBP4 latent transforming growth factor beta binding protein 4 1.76468
TMEM59 transmembrane protein 59 1.75468
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 1.75427
DOCK1 dedicator of cytokinesis 1 1.75255
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.75156
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.74972
SPRR2C small proline-rich protein 2C (pseudogene) 1.74902
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 1.74607
UCN urocortin 1.7363
SQLE squalene epoxidase 1.72979
NOS2 nitric oxide synthase 2, inducible 1.72748
DPYSL4 dihydropyrimidinase-like 4 1.72531
EGR1 early growth response 1 1.72302
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.72199
HPCA hippocalcin 1.71828
INPP1 inositol polyphosphate-1-phosphatase 1.71496
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.71429
C1ORF105 chromosome 1 open reading frame 105 1.71098
PVT1 Pvt1 oncogene (non-protein coding) 1.7104
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.70786
CSK c-src tyrosine kinase 1.70078
RBMY1E RNA binding motif protein, Y-linked, family 1, member E 1.69607
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.69303
IRF6 interferon regulatory factor 6 1.69281
SYNPO synaptopodin 1.6911
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 1.68946
GCAT glycine C-acetyltransferase 1.68709
DEDD death effector domain containing 1.68643
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 1.68473
CNTN2 contactin 2 (axonal) 1.68251
FAF2 Fas associated factor family member 2 1.67787
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.67505
MEIS3P1 Meis homeobox 3 pseudogene 1 1.67397
CDR2L cerebellar degeneration-related protein 2-like 1.66985
DMBT1 deleted in malignant brain tumors 1 1.66605
NLE1 notchless homolog 1 (Drosophila) 1.66552
AURKB aurora kinase B 1.66542
LTB4R leukotriene B4 receptor 1.66463
RBMXL2 RNA binding motif protein, X-linked-like 2 1.66391
RRAGD Ras-related GTP binding D 1.66266
SAMD14 sterile alpha motif domain containing 14 1.66245
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.66044
RPS10 ribosomal protein S10 1.65632
PITPNA phosphatidylinositol transfer protein, alpha 1.6557
TRIM21 tripartite motif containing 21 1.65287
PSG11 pregnancy specific beta-1-glycoprotein 11 1.64953
CHD8 chromodomain helicase DNA binding protein 8 1.6453
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.6437
C2ORF72 chromosome 2 open reading frame 72 1.64046
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.63949
TXNRD1 thioredoxin reductase 1 1.63643
PRELP proline/arginine-rich end leucine-rich repeat protein 1.63194
KDM5C lysine (K)-specific demethylase 5C 1.62968
CLTC clathrin, heavy chain (Hc) 1.62819
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.62227
NRP2 neuropilin 2 1.62051
MMP11 matrix metallopeptidase 11 1.61712
PAX3 paired box 3 1.61678
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 1.61621
KRT8 keratin 8, type II 1.61187
RUNX1 runt-related transcription factor 1 1.61094
MID2 midline 2 1.60912
GPC3 glypican 3 1.60807
ZNF337 zinc finger protein 337 1.60739
LDB1 LIM domain binding 1 1.60579
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.60312
CLSTN3 calsyntenin 3 1.59822
GRP gastrin-releasing peptide 1.59526
DPF2 D4, zinc and double PHD fingers family 2 1.58609
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.58455
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 1.5828
CSN2 casein beta 1.5811
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.58029
SRSF3 serine/arginine-rich splicing factor 3 1.58023
NEMF nuclear export mediator factor 1.58021
ADRA1D adrenoceptor alpha 1D 1.57876
IL5RA interleukin 5 receptor, alpha 1.57818
SFN stratifin 1.57727
AQP5 aquaporin 5 1.57196
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 1.57087
MUC1 mucin 1, cell surface associated 1.57024
ATP10B ATPase, class V, type 10B 1.56929
LDOC1 leucine zipper, down-regulated in cancer 1 1.56919
VENTX VENT homeobox 1.56918
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 1.56669
LINC00667 long intergenic non-protein coding RNA 667 1.56542
GRAMD1B GRAM domain containing 1B 1.56478
MXRA8 matrix-remodelling associated 8 1.56475
RAP1GAP2 RAP1 GTPase activating protein 2 1.56246
SEZ6L seizure related 6 homolog (mouse)-like 1.56013
CLCN2 chloride channel, voltage-sensitive 2 1.55744
MYO9B myosin IXB 1.55626
HSF4 heat shock transcription factor 4 1.55604
CD5L CD5 molecule-like 1.5558
GATA4 GATA binding protein 4 1.55302
NPPB natriuretic peptide B 1.54943
JAG1 jagged 1 1.54817
COL8A1 collagen, type VIII, alpha 1 1.54795
GTF2B general transcription factor IIB 1.54768
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1.54486
EGR2 early growth response 2 1.54415
PDE8A phosphodiesterase 8A 1.54169
MAPT microtubule-associated protein tau 1.53689
LEPROT leptin receptor overlapping transcript 1.53597
TRIP11 thyroid hormone receptor interactor 11 1.5294
FAM189B family with sequence similarity 189, member B 1.52763
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 1.52234
SLC10A3 solute carrier family 10, member 3 1.51584
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.51476
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 1.51304
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.51203
HMGB2 high mobility group box 2 1.51043
RPL35 ribosomal protein L35 1.51007
CCKBR cholecystokinin B receptor 1.51004
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 1.50958
HMG20B high mobility group 20B 1.50886
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.5073
TRAFD1 TRAF-type zinc finger domain containing 1 1.50372
OR2J2 olfactory receptor, family 2, subfamily J, member 2 1.50277
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 1.49944
C9ORF16 chromosome 9 open reading frame 16 1.49828
CXCL5 chemokine (C-X-C motif) ligand 5 1.49818
NKX2-1 NK2 homeobox 1 1.49625
MPPED1 metallophosphoesterase domain containing 1 1.4955
DBT dihydrolipoamide branched chain transacylase E2 1.49337
GJB3 gap junction protein, beta 3, 31kDa 1.49117
MNT MAX network transcriptional repressor 1.48564
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 1.48537
ALPI alkaline phosphatase, intestinal 1.48507
PTMS parathymosin 1.48421
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.48362
CETP cholesteryl ester transfer protein, plasma 1.48316
MC5R melanocortin 5 receptor 1.48281
HBS1L HBS1-like translational GTPase 1.4826
ERBB4 erb-b2 receptor tyrosine kinase 4 1.48191
RYR3 ryanodine receptor 3 1.47565
CHD9 chromodomain helicase DNA binding protein 9 1.47547
BMP1 bone morphogenetic protein 1 1.47271
SYN1 synapsin I 1.46913
CASC3 cancer susceptibility candidate 3 1.46874
HCRTR2 hypocretin (orexin) receptor 2 1.46785
SEC62 SEC62 homolog (S. cerevisiae) 1.46551
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.46457
FAM175B family with sequence similarity 175, member B 1.46353
FH fumarate hydratase 1.46179
FGFR1 fibroblast growth factor receptor 1 1.4606
MUC3A mucin 3A, cell surface associated 1.4598
ACTB actin, beta 1.45956
FSHR follicle stimulating hormone receptor 1.45905
EDC4 enhancer of mRNA decapping 4 1.45865
CIB2 calcium and integrin binding family member 2 1.45832
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.4577

decreased expression

Symbol Name Standardized Value
CAPZB capping protein (actin filament) muscle Z-line, beta -3.7339
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -3.08316
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.91025
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 -2.84636
MARS methionyl-tRNA synthetase -2.81669
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -2.75159
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.61876
DAPK3 death-associated protein kinase 3 -2.59582
UBE2M ubiquitin-conjugating enzyme E2M -2.57725
PDAP1 PDGFA associated protein 1 -2.53479
SRP72 signal recognition particle 72kDa -2.51577
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.50689
PTEN phosphatase and tensin homolog -2.4785
BAG6 BCL2-associated athanogene 6 -2.40836
ZNF76 zinc finger protein 76 -2.38533
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.37377
PTPRA protein tyrosine phosphatase, receptor type, A -2.35542
PARP2 poly (ADP-ribose) polymerase 2 -2.34442
FAM193A family with sequence similarity 193, member A -2.31796
ALAS1 5'-aminolevulinate synthase 1 -2.28875
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -2.28874
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.24435
KLHL18 kelch-like family member 18 -2.23831
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -2.22287
PEX6 peroxisomal biogenesis factor 6 -2.20913
KAT6A K(lysine) acetyltransferase 6A -2.17676
SENP5 SUMO1/sentrin specific peptidase 5 -2.16686
BAG1 BCL2-associated athanogene -2.15093
CDX4 caudal type homeobox 4 -2.14684
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -2.14567
AFG3L1P AFG3-like AAA ATPase 1, pseudogene -2.12873
PPP6R1 protein phosphatase 6, regulatory subunit 1 -2.11694
MFN1 mitofusin 1 -2.11175
LMNB2 lamin B2 -2.09877
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -2.07956
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.07606
STAU1 staufen double-stranded RNA binding protein 1 -2.07435
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -2.069
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) -2.05093
RNASEH2B ribonuclease H2, subunit B -2.04667
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -2.03957
C1ORF216 chromosome 1 open reading frame 216 -2.03922
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.03605
HMGN2 high mobility group nucleosomal binding domain 2 -2.02941
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -2.02351
EIF3I eukaryotic translation initiation factor 3, subunit I -2.02059
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.01515
TXN thioredoxin -2.0118
TRAPPC10 trafficking protein particle complex 10 -2.00898
CLTB clathrin, light chain B -2.0082
TTLL12 tubulin tyrosine ligase-like family member 12 -1.99454
PML promyelocytic leukemia -1.98717
RAD23B RAD23 homolog B (S. cerevisiae) -1.98659
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.98514
PGAP2 post-GPI attachment to proteins 2 -1.97053
ZNF32 zinc finger protein 32 -1.96274
TMED9 transmembrane emp24 protein transport domain containing 9 -1.94843
DLG5 discs, large homolog 5 (Drosophila) -1.94672
PUF60 poly-U binding splicing factor 60KDa -1.94407
CAST calpastatin -1.94359
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -1.93924
PNRC1 proline-rich nuclear receptor coactivator 1 -1.9378
WWOX WW domain containing oxidoreductase -1.93501
NR2F6 nuclear receptor subfamily 2, group F, member 6 -1.93264
LMF2 lipase maturation factor 2 -1.93036
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -1.92541
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -1.92351
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -1.92164
SEC63 SEC63 homolog (S. cerevisiae) -1.91754
MBD2 methyl-CpG binding domain protein 2 -1.91319
DAZAP2 DAZ associated protein 2 -1.91214
RNASEH2A ribonuclease H2, subunit A -1.90835
TET3 tet methylcytosine dioxygenase 3 -1.90552
CLIP1 CAP-GLY domain containing linker protein 1 -1.90304
KATNA1 katanin p60 (ATPase containing) subunit A 1 -1.90197
RWDD3 RWD domain containing 3 -1.8974
TIMELESS timeless circadian clock -1.89495
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -1.87647
USP6NL USP6 N-terminal like -1.87254
STIM1 stromal interaction molecule 1 -1.87041
TATDN2 TatD DNase domain containing 2 -1.86918
COPA coatomer protein complex, subunit alpha -1.85962
HAB1 B1 for mucin -1.85482
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -1.84879
PLIN3 perilipin 3 -1.83943
NME1 NME/NM23 nucleoside diphosphate kinase 1 -1.83876
NPC1 Niemann-Pick disease, type C1 -1.83658
EMD emerin -1.83519
ANKLE2 ankyrin repeat and LEM domain containing 2 -1.82897
NUCB2 nucleobindin 2 -1.82573
NR2C1 nuclear receptor subfamily 2, group C, member 1 -1.81658
JUP junction plakoglobin -1.81575
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.81264
PFDN1 prefoldin subunit 1 -1.80563
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -1.80507
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -1.80099
ATG5 autophagy related 5 -1.79925
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -1.79662
ZFPL1 zinc finger protein-like 1 -1.79561
CREBZF CREB/ATF bZIP transcription factor -1.78949
PHB prohibitin -1.7828
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.7801
RBM19 RNA binding motif protein 19 -1.77694
RPP30 ribonuclease P/MRP 30kDa subunit -1.77627
ILVBL ilvB (bacterial acetolactate synthase)-like -1.76303
CAPNS1 calpain, small subunit 1 -1.76205
TUBB4A tubulin, beta 4A class IVa -1.76143
SEC24C SEC24 family member C -1.76108
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 -1.76013
RPL36AL ribosomal protein L36a-like -1.76007
KAT7 K(lysine) acetyltransferase 7 -1.75375
C5ORF15 chromosome 5 open reading frame 15 -1.74443
CALM1 calmodulin 1 (phosphorylase kinase, delta) -1.74182
CDC37 cell division cycle 37 -1.74041
JAK1 Janus kinase 1 -1.73956
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -1.73828
MARK3 MAP/microtubule affinity-regulating kinase 3 -1.73637
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -1.72767
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -1.72755
TCF3 transcription factor 3 -1.72578
PHF21A PHD finger protein 21A -1.72418
RHOA ras homolog family member A -1.72414
STARD3 StAR-related lipid transfer (START) domain containing 3 -1.71392
PPIB peptidylprolyl isomerase B (cyclophilin B) -1.70956
PRDM2 PR domain containing 2, with ZNF domain -1.7075
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -1.70218
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.70125
OAZ2 ornithine decarboxylase antizyme 2 -1.69948
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -1.69714
ARR3 arrestin 3, retinal (X-arrestin) -1.69318
RBBP8 retinoblastoma binding protein 8 -1.6922
KIAA0430 KIAA0430 -1.68917
CKAP5 cytoskeleton associated protein 5 -1.68895
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.68627
PCBP2 poly(rC) binding protein 2 -1.68498
HSF1 heat shock transcription factor 1 -1.68493
CUL1 cullin 1 -1.67865
STAG1 stromal antigen 1 -1.67856
BTN2A1 butyrophilin, subfamily 2, member A1 -1.67755
SIAH2 siah E3 ubiquitin protein ligase 2 -1.677
TSPYL1 TSPY-like 1 -1.67663
EIF6 eukaryotic translation initiation factor 6 -1.67244
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -1.66938
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -1.66652
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -1.66639
NONO non-POU domain containing, octamer-binding -1.66282
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -1.66035
GLG1 golgi glycoprotein 1 -1.65896
HLA-E major histocompatibility complex, class I, E -1.6584
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -1.65732
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -1.65598
RABEPK Rab9 effector protein with kelch motifs -1.65459
BIRC2 baculoviral IAP repeat containing 2 -1.65404
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -1.65349
HLA-A major histocompatibility complex, class I, A -1.6493
SMNDC1 survival motor neuron domain containing 1 -1.64659
TLK1 tousled-like kinase 1 -1.63996
CIAO1 cytosolic iron-sulfur assembly component 1 -1.63832
UBE2S ubiquitin-conjugating enzyme E2S -1.63667
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.63599
NACA nascent polypeptide-associated complex alpha subunit -1.63166
SAMD4A sterile alpha motif domain containing 4A -1.63024
CSNK2A1 casein kinase 2, alpha 1 polypeptide -1.62877
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -1.6222
MAPK3 mitogen-activated protein kinase 3 -1.6172
FUBP3 far upstream element (FUSE) binding protein 3 -1.61229
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -1.60544
RAB5C RAB5C, member RAS oncogene family -1.60456
HLF hepatic leukemia factor -1.60132
NPAT nuclear protein, ataxia-telangiectasia locus -1.60126
RPS24 ribosomal protein S24 -1.5981
CCNI cyclin I -1.59788
BAIAP2 BAI1-associated protein 2 -1.59744
PRPF3 pre-mRNA processing factor 3 -1.59254
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -1.5913
F7 coagulation factor VII (serum prothrombin conversion accelerator) -1.58706
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.58524
FBLN2 fibulin 2 -1.58008
PGGT1B protein geranylgeranyltransferase type I, beta subunit -1.57982
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -1.57973
NCOR2 nuclear receptor corepressor 2 -1.57872
DGUOK deoxyguanosine kinase -1.57578
SRSF4 serine/arginine-rich splicing factor 4 -1.57509
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -1.57136
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -1.57009
DCTN2 dynactin 2 (p50) -1.56528
SLAMF1 signaling lymphocytic activation molecule family member 1 -1.56507
FUBP1 far upstream element (FUSE) binding protein 1 -1.5639
TES testin LIM domain protein -1.56348
BCL7A B-cell CLL/lymphoma 7A -1.56176
GTF2A2 general transcription factor IIA, 2, 12kDa -1.56113
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -1.55849
MOB1A MOB kinase activator 1A -1.55826
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -1.55692
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -1.5561
TRIM3 tripartite motif containing 3 -1.55316
TDRD7 tudor domain containing 7 -1.54841
SARDH sarcosine dehydrogenase -1.54775
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma -1.54716
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.53702
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -1.53581
PREP prolyl endopeptidase -1.53569
NCOA2 nuclear receptor coactivator 2 -1.53492
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -1.53312
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.52966
CYHR1 cysteine/histidine-rich 1 -1.52927
COX7C cytochrome c oxidase subunit VIIc -1.52763
DPYSL3 dihydropyrimidinase-like 3 -1.52283
NQO2 NAD(P)H dehydrogenase, quinone 2 -1.52038
KIF13B kinesin family member 13B -1.51968
TELO2 telomere maintenance 2 -1.51907
HDAC5 histone deacetylase 5 -1.51778
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -1.51672
XPOT exportin, tRNA -1.51642
SPEN spen family transcriptional repressor -1.51421
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -1.51331
MYCNOS MYCN opposite strand -1.51096
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -1.50701
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.50555
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.50469
MEN1 multiple endocrine neoplasia I -1.50178
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.5004
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -1.49755
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.4975
PHF20 PHD finger protein 20 -1.49677
SUMO2 small ubiquitin-like modifier 2 -1.49439
API5 apoptosis inhibitor 5 -1.49148
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -1.4893
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.4879
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.48645
TCEA2 transcription elongation factor A (SII), 2 -1.48418
RPN1 ribophorin I -1.48392
IL2RB interleukin 2 receptor, beta -1.48329
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -1.48242
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -1.47882
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -1.47856
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -1.47305
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -1.47204
SEC23A Sec23 homolog A (S. cerevisiae) -1.47029
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -1.47006
RAP1B RAP1B, member of RAS oncogene family -1.46825
NCOA1 nuclear receptor coactivator 1 -1.46477
BSG basigin (Ok blood group) -1.46347
ELAC2 elaC ribonuclease Z 2 -1.46047
ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E -1.45966
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.45886
TSC22D2 TSC22 domain family, member 2 -1.4577
HLA-DMB major histocompatibility complex, class II, DM beta -1.45683
KLF11 Kruppel-like factor 11 -1.45666
DSTNP2 destrin (actin depolymerizing factor) pseudogene 2 -1.45602
TGFB1 transforming growth factor, beta 1 -1.45376
COL10A1 collagen, type X, alpha 1 -1.45071
ALPL alkaline phosphatase, liver/bone/kidney -1.4498
SYF2 SYF2 pre-mRNA-splicing factor -1.44862
DBN1 drebrin 1 -1.4485
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) -1.44792
NMB neuromedin B -1.44657
CALCB calcitonin-related polypeptide beta -1.44527
USO1 USO1 vesicle transport factor -1.44502
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -1.44347
SON SON DNA binding protein -1.44253
UNC119 unc-119 homolog (C. elegans) -1.44054
NOS3 nitric oxide synthase 3 (endothelial cell) -1.43903
TECR trans-2,3-enoyl-CoA reductase -1.43715
HLA-DRA major histocompatibility complex, class II, DR alpha -1.436
PLAGL2 pleiomorphic adenoma gene-like 2 -1.43026
HDAC6 histone deacetylase 6 -1.42784
PRM2 protamine 2 -1.4243
IRGC immunity-related GTPase family, cinema -1.42372
FOXM1 forkhead box M1 -1.42195
SNRPG small nuclear ribonucleoprotein polypeptide G -1.42154
RFC4 replication factor C (activator 1) 4, 37kDa -1.42083
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -1.41949
TSPAN3 tetraspanin 3 -1.41886
LPAR2 lysophosphatidic acid receptor 2 -1.41864
PDIA3 protein disulfide isomerase family A, member 3 -1.41856
PTMA prothymosin, alpha -1.4175
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -1.41721
FIBP fibroblast growth factor (acidic) intracellular binding protein -1.41695
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -1.41646
GRM2 glutamate receptor, metabotropic 2 -1.41426
TESK1 testis-specific kinase 1 -1.414
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -1.41237
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -1.40987
SURF1 surfeit 1 -1.40753
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -1.40735
USP20 ubiquitin specific peptidase 20 -1.40455
NXF1 nuclear RNA export factor 1 -1.40315
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -1.40202
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.40191
SF3A2 splicing factor 3a, subunit 2, 66kDa -1.40135
FEM1C fem-1 homolog c (C. elegans) -1.40094
SYNJ2 synaptojanin 2 -1.40001
FAM8A1 family with sequence similarity 8, member A1 -1.39672
BRPF1 bromodomain and PHD finger containing, 1 -1.39281
RANBP6 RAN binding protein 6 -1.3927
CTSH cathepsin H -1.38933
RALY RALY heterogeneous nuclear ribonucleoprotein -1.38602
ZNF85 zinc finger protein 85 -1.38517
ASCL2 achaete-scute family bHLH transcription factor 2 -1.38346
Funding