| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemetrexed perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pemetrexed_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.161375 |
| FAM13A | family with sequence similarity 13, member A | 0.135396 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0882867 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0836935 |
| HELZ | helicase with zinc finger | 0.0786448 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0764645 |
| MEF2A | myocyte enhancer factor 2A | 0.0723168 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0717294 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0690699 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0670396 |
| MSI2 | musashi RNA-binding protein 2 | 0.0662252 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0647828 |
| COL3A1 | collagen, type III, alpha 1 | 0.0638887 |
| PTK2 | protein tyrosine kinase 2 | 0.0623939 |
| SEPTIN9 | septin 9 | 0.0607594 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0579452 |
| DSCAM | Down syndrome cell adhesion molecule | 0.056894 |
| XPO1 | exportin 1 | 0.0560725 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0554207 |
| TRIB2 | tribbles pseudokinase 2 | 0.0543115 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0536887 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0528978 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0525901 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0519468 |
| LPIN1 | lipin 1 | 0.0517591 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0512018 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0511201 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0506934 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0496619 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0489766 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.048052 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0468745 |
| CCND1 | cyclin D1 | 0.0459627 |
| DTNA | dystrobrevin, alpha | 0.0456539 |
| PGK1 | phosphoglycerate kinase 1 | 0.0429783 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0424918 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0409019 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0399926 |
| TOP1 | topoisomerase (DNA) I | 0.0398447 |
| SPAG9 | sperm associated antigen 9 | 0.0396246 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0392155 |
| VIM | vimentin | 0.0390571 |
| CCNY | cyclin Y | 0.0388496 |
| ASPH | aspartate beta-hydroxylase | 0.0382562 |
| PKM | pyruvate kinase, muscle | 0.0371411 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0369849 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0368804 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0366627 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0365827 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0364036 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0363738 |
| RNF213 | ring finger protein 213 | 0.0363652 |
| PRKCE | protein kinase C, epsilon | 0.0363024 |
| SMAD3 | SMAD family member 3 | 0.0361709 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0357284 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0340008 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0338209 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0338175 |
| RPL4 | ribosomal protein L4 | 0.0330972 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0330623 |
| WDR43 | WD repeat domain 43 | 0.0326827 |
| WDR45B | WD repeat domain 45B | 0.0325481 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0321024 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0320248 |
| PLCB4 | phospholipase C, beta 4 | 0.0317043 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0314895 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0314811 |
| AOPEP | aminopeptidase O (putative) | 0.0312893 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0311196 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0311064 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0306222 |
| NBAS | neuroblastoma amplified sequence | 0.0303931 |
| CASC3 | cancer susceptibility candidate 3 | 0.0303178 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0300854 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0299231 |
| CDH13 | cadherin 13 | 0.0297586 |
| RHOA | ras homolog family member A | 0.029534 |
| ARRDC3 | arrestin domain containing 3 | 0.0293605 |
| ANXA2 | annexin A2 | 0.0291603 |
| AHNAK | AHNAK nucleoprotein | 0.0289236 |
| PDE8A | phosphodiesterase 8A | 0.0285469 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0284884 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0282601 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0280755 |
| FMN1 | formin 1 | 0.0280156 |
| RPL23 | ribosomal protein L23 | 0.0279788 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0276395 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0274064 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0273192 |
| APP | amyloid beta (A4) precursor protein | 0.0270219 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0269445 |
| USP3 | ubiquitin specific peptidase 3 | 0.0267536 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0265307 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.026429 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0263195 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0262192 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0260972 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0259805 |
| CLTC | clathrin, heavy chain (Hc) | 0.0259391 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0256428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.354502 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127726 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.12051 |
| SYT1 | synaptotagmin I | -0.100798 |
| VCL | vinculin | -0.0853816 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0661638 |
| SIK2 | salt-inducible kinase 2 | -0.0597615 |
| TLE4 | transducin-like enhancer of split 4 | -0.0584194 |
| VMP1 | vacuole membrane protein 1 | -0.0584039 |
| GLCCI1 | glucocorticoid induced 1 | -0.0528251 |
| MEIS2 | Meis homeobox 2 | -0.0491714 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0487837 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0480798 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0466842 |
| BPTF | bromodomain PHD finger transcription factor | -0.0449422 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0435346 |
| KLHL13 | kelch-like family member 13 | -0.0427862 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0410281 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0391802 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0387428 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0375187 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0367261 |
| EGR1 | early growth response 1 | -0.0366083 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0356339 |
| FTL | ferritin, light polypeptide | -0.0350773 |
| MAP1B | microtubule-associated protein 1B | -0.0347313 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.034106 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0340786 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0340501 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0334952 |
| STK38L | serine/threonine kinase 38 like | -0.0331395 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0322694 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0321736 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0307081 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0302833 |
| PLPP1 | phospholipid phosphatase 1 | -0.0297275 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0290892 |
| RPL28 | ribosomal protein L28 | -0.028989 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0288983 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0287094 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0283994 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0280388 |
| GAB2 | GRB2-associated binding protein 2 | -0.0277528 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0275219 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0269893 |
| RPS12 | ribosomal protein S12 | -0.0267769 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.026732 |
| THBS1 | thrombospondin 1 | -0.0267175 |
| FHIT | fragile histidine triad | -0.0266385 |
| UBAP2 | ubiquitin associated protein 2 | -0.0263525 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0263118 |
| MBTD1 | mbt domain containing 1 | -0.0262665 |
| PCDH17 | protocadherin 17 | -0.0256726 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0253643 |
| ANGPT1 | angiopoietin 1 | -0.0252577 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0251222 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.02464 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0246252 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0246057 |
| SCFD1 | sec1 family domain containing 1 | -0.0244418 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0243525 |
| AEBP2 | AE binding protein 2 | -0.0238061 |
| FRMD4A | FERM domain containing 4A | -0.0233928 |
| CALD1 | caldesmon 1 | -0.023279 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0229693 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0228017 |
| TBX2 | T-box 2 | -0.0226086 |
| GNAS | GNAS complex locus | -0.0225976 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0224457 |
| INTS6 | integrator complex subunit 6 | -0.0224428 |
| FHL2 | four and a half LIM domains 2 | -0.0222551 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0220675 |
| RPL36 | ribosomal protein L36 | -0.0219359 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0219236 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0218825 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0218478 |
| RPLP1 | ribosomal protein, large, P1 | -0.0217916 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0216399 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0214602 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0213333 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0212319 |
| RALYL | RALY RNA binding protein-like | -0.0210428 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0209632 |
| RACK1 | receptor for activated C kinase 1 | -0.0207504 |
| RPS3 | ribosomal protein S3 | -0.0204668 |
| RPS6 | ribosomal protein S6 | -0.0203929 |
| NBEA | neurobeachin | -0.02039 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0200972 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0200626 |
| ATRNL1 | attractin-like 1 | -0.0200002 |
| POTEF | POTE ankyrin domain family, member F | -0.0199451 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0197659 |
| FERMT2 | fermitin family member 2 | -0.0196351 |
| CDK13 | cyclin-dependent kinase 13 | -0.0196253 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0195502 |
| RPL12 | ribosomal protein L12 | -0.0194335 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -0.0194109 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0193719 |
| PCBP3 | poly(rC) binding protein 3 | -0.0191904 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0189677 |
