| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemetrexed perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pemetrexed_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.158628 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.100059 |
| NAV2 | neuron navigator 2 | 0.0647816 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0542159 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0540059 |
| FLNA | filamin A, alpha | 0.0419492 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0386387 |
| OGA | O-GlcNAcase | 0.0376996 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0367235 |
| FNDC3B | fibronectin type III domain containing 3B | 0.035758 |
| ARRDC3 | arrestin domain containing 3 | 0.0329485 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0325439 |
| MSN | moesin | 0.0304793 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0297588 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0279203 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0268292 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0246812 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0215407 |
| CEP250 | centrosomal protein 250kDa | 0.0215334 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0201782 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0194864 |
| MYOF | myoferlin | 0.0193848 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0191765 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0191466 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0185734 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0183273 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0177796 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0176797 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0175297 |
| ANLN | anillin, actin binding protein | 0.0170022 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0168751 |
| SPAG9 | sperm associated antigen 9 | 0.0168531 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0168437 |
| DUSP5 | dual specificity phosphatase 5 | 0.016477 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.0158949 |
| WTAP | Wilms tumor 1 associated protein | 0.015611 |
| XPO1 | exportin 1 | 0.0156024 |
| RLIM | ring finger protein, LIM domain interacting | 0.01528 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0152004 |
| ACTN4 | actinin, alpha 4 | 0.0147945 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0146038 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0145976 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0140611 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0139465 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0138807 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0137978 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0137284 |
| CADM1 | cell adhesion molecule 1 | 0.0136592 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0135896 |
| PCBP2 | poly(rC) binding protein 2 | 0.0131807 |
| HELZ | helicase with zinc finger | 0.0129442 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0129342 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0128371 |
| OPTN | optineurin | 0.0128011 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0128011 |
| USP12 | ubiquitin specific peptidase 12 | 0.0127342 |
| NUP153 | nucleoporin 153kDa | 0.0123801 |
| SUCO | SUN domain containing ossification factor | 0.0123298 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0123285 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0123063 |
| MKI67 | marker of proliferation Ki-67 | 0.0122576 |
| APP | amyloid beta (A4) precursor protein | 0.0122393 |
| KIAA1217 | KIAA1217 | 0.0121885 |
| FLNB | filamin B, beta | 0.012021 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0118891 |
| ADAR | adenosine deaminase, RNA-specific | 0.011731 |
| CENPF | centromere protein F, 350/400kDa | 0.0117034 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.0115705 |
| TDRD7 | tudor domain containing 7 | 0.0113358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.011314 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0113 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0112826 |
| ATP13A3 | ATPase type 13A3 | 0.0112418 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0110947 |
| SERINC1 | serine incorporator 1 | 0.0110433 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0110091 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0110051 |
| MX1 | MX dynamin-like GTPase 1 | 0.010934 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0109251 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0109192 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0109091 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0108671 |
| TFG | TRK-fused gene | 0.0108525 |
| YTHDC1 | YTH domain containing 1 | 0.0107519 |
| YEATS2 | YEATS domain containing 2 | 0.010675 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0106712 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0106492 |
| NONO | non-POU domain containing, octamer-binding | 0.0105238 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0105158 |
| SMAD3 | SMAD family member 3 | 0.0105103 |
| YME1L1 | YME1-like 1 ATPase | 0.010436 |
| KLF6 | Kruppel-like factor 6 | 0.0104352 |
| TPM3 | tropomyosin 3 | 0.0104253 |
| DIAPH3 | diaphanous-related formin 3 | 0.0103432 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0102985 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0102767 |
| H1-2 | H1.2 linker histone, cluster member | 0.0102501 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0102021 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0101291 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0100803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.247713 |
| GLIS3 | GLIS family zinc finger 3 | -0.177178 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163047 |
| HLA-B | major histocompatibility complex, class I, B | -0.157741 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.141042 |
| CD44 | CD44 molecule (Indian blood group) | -0.124857 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.117889 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.110223 |
| HMGA2 | high mobility group AT-hook 2 | -0.10408 |
| FTL | ferritin, light polypeptide | -0.10393 |
| FRMD4A | FERM domain containing 4A | -0.103767 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.103683 |
| IER3 | immediate early response 3 | -0.102132 |
| TMSB10 | thymosin beta 10 | -0.101786 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0931592 |
| BICC1 | BicC family RNA binding protein 1 | -0.0859097 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0825993 |
| VCAN | versican | -0.0798099 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0782522 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0697343 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0695538 |
| HLA-A | major histocompatibility complex, class I, A | -0.0677668 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0657535 |
| CDH13 | cadherin 13 | -0.0647913 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0646574 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0639421 |
| RPS6 | ribosomal protein S6 | -0.0605137 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.057788 |
| RAI14 | retinoic acid induced 14 | -0.0577068 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0564858 |
| MT2A | metallothionein 2A | -0.0564395 |
| LDHA | lactate dehydrogenase A | -0.0550149 |
| DST | dystonin | -0.0538143 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0527957 |
| CTSD | cathepsin D | -0.0505497 |
| EGR1 | early growth response 1 | -0.0503416 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0498076 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0490262 |
| RPL37A | ribosomal protein L37a | -0.0475938 |
| NAV1 | neuron navigator 1 | -0.0475746 |
| VCL | vinculin | -0.0470989 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0464468 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0464088 |
| RPS8 | ribosomal protein S8 | -0.0461938 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0458688 |
| AHNAK | AHNAK nucleoprotein | -0.0450377 |
| ENO1 | enolase 1, (alpha) | -0.0449742 |
| B2M | beta-2-microglobulin | -0.0433877 |
| RPLP2 | ribosomal protein, large, P2 | -0.0430907 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0429898 |
| COL1A1 | collagen, type I, alpha 1 | -0.0428447 |
| CALR | calreticulin | -0.042779 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0421195 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0421111 |
| RPS12 | ribosomal protein S12 | -0.0418686 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0416759 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0410686 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.041001 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0406165 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0402393 |
| NDRG1 | N-myc downstream regulated 1 | -0.0400494 |
| LOX | lysyl oxidase | -0.0400185 |
| ASPH | aspartate beta-hydroxylase | -0.0398485 |
| DIAPH2 | diaphanous-related formin 2 | -0.0396396 |
| RPL35A | ribosomal protein L35a | -0.0393288 |
| TNS3 | tensin 3 | -0.0388242 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0382976 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0381287 |
| ACTG1 | actin gamma 1 | -0.037996 |
| PTMA | prothymosin, alpha | -0.0379813 |
| RPLP1 | ribosomal protein, large, P1 | -0.0378902 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0378833 |
| RPS24 | ribosomal protein S24 | -0.0376184 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0374022 |
| TPM4 | tropomyosin 4 | -0.0366974 |
| RPL36A | ribosomal protein L36a | -0.0359381 |
| VMP1 | vacuole membrane protein 1 | -0.0346401 |
| CLMP | CXADR-like membrane protein | -0.0344829 |
| STC1 | stanniocalcin 1 | -0.0344696 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0342032 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0340742 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0338503 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0335889 |
| RPS3 | ribosomal protein S3 | -0.0335358 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0332264 |
| EFNA5 | ephrin-A5 | -0.0325745 |
| CANX | calnexin | -0.032083 |
| RACK1 | receptor for activated C kinase 1 | -0.0319959 |
| ATXN1 | ataxin 1 | -0.0319347 |
| TMEM132D | transmembrane protein 132D | -0.0318755 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0318067 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0316997 |
| RPS13 | ribosomal protein S13 | -0.0316955 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0316556 |
| RPL9 | ribosomal protein L9 | -0.0315149 |
| PGK1 | phosphoglycerate kinase 1 | -0.0314244 |
| CTSB | cathepsin B | -0.0312175 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0309225 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0308077 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0307131 |
