| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pemigatinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.22657 |
| EXT1 | exostosin glycosyltransferase 1 | 0.187959 |
| INTS6 | integrator complex subunit 6 | 0.12961 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.128385 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0984087 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0864679 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0836183 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0806909 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0803811 |
| SMAD3 | SMAD family member 3 | 0.0791924 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0781313 |
| MX1 | MX dynamin-like GTPase 1 | 0.0728344 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0725752 |
| MYO1E | myosin IE | 0.0719757 |
| ANXA2 | annexin A2 | 0.0707096 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0691975 |
| TMC5 | transmembrane channel-like 5 | 0.0690949 |
| MCU | mitochondrial calcium uniporter | 0.0687442 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0673054 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0662669 |
| VCL | vinculin | 0.0655823 |
| RNF213 | ring finger protein 213 | 0.0654599 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0650002 |
| TJP1 | tight junction protein 1 | 0.0636696 |
| FNIP2 | folliculin interacting protein 2 | 0.0633786 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0619499 |
| HKDC1 | hexokinase domain containing 1 | 0.061263 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0598373 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0586479 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0577549 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0549231 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0548838 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0535971 |
| SIK3 | SIK family kinase 3 | 0.0535883 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0535728 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0523176 |
| MX2 | MX dynamin-like GTPase 2 | 0.0513175 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0509841 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0508248 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0507988 |
| LAMA4 | laminin, alpha 4 | 0.049652 |
| ERBIN | erbb2 interacting protein | 0.0492378 |
| PHF3 | PHD finger protein 3 | 0.0491157 |
| RIGI | RNA sensor RIG-I | 0.0489322 |
| PLSCR1 | phospholipid scramblase 1 | 0.0482464 |
| KYNU | kynureninase | 0.0479741 |
| LCN2 | lipocalin 2 | 0.0473919 |
| SERINC5 | serine incorporator 5 | 0.0464701 |
| ZNF292 | zinc finger protein 292 | 0.0463524 |
| DIAPH1 | diaphanous-related formin 1 | 0.0461787 |
| ATP11A | ATPase, class VI, type 11A | 0.0453375 |
| SPATA13 | spermatogenesis associated 13 | 0.0448211 |
| IFNGR1 | interferon gamma receptor 1 | 0.0435172 |
| TRIM2 | tripartite motif containing 2 | 0.0431393 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0424897 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0413025 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0410656 |
| STK24 | serine/threonine kinase 24 | 0.040805 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0408035 |
| SPAG9 | sperm associated antigen 9 | 0.0393768 |
| GOLGB1 | golgin B1 | 0.0389074 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0388575 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0382041 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0377429 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0376666 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0374832 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0374367 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0374184 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0368896 |
| VMP1 | vacuole membrane protein 1 | 0.0368582 |
| JAK1 | Janus kinase 1 | 0.0367511 |
| RASAL2 | RAS protein activator like 2 | 0.0366682 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0366207 |
| RBM47 | RNA binding motif protein 47 | 0.0359075 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0354997 |
| PRKCA | protein kinase C, alpha | 0.0352416 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0350523 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0350435 |
| TOP1 | topoisomerase (DNA) I | 0.03499 |
| MAP7 | microtubule-associated protein 7 | 0.0346717 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0345144 |
| ADAR | adenosine deaminase, RNA-specific | 0.0337736 |
| EPHB2 | EPH receptor B2 | 0.0335136 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0333245 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.032527 |
| EFNB2 | ephrin-B2 | 0.0323129 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0321276 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0321019 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0320337 |
| MCL1 | myeloid cell leukemia 1 | 0.0316695 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.031516 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0311045 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0306793 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0304848 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0302174 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0300768 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0300118 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.029888 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0296018 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0293079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108387 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.077017 |
| PTMA | prothymosin, alpha | -0.064014 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0635734 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0624478 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0512178 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0496259 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0479722 |
| RNF149 | ring finger protein 149 | -0.046849 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0427708 |
| NDRG1 | N-myc downstream regulated 1 | -0.0427352 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.041318 |
| WDR45B | WD repeat domain 45B | -0.0367817 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0357579 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0337955 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.03222 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0314553 |
| H1-0 | H1.0 linker histone | -0.0293261 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0287643 |
| GNAS | GNAS complex locus | -0.02865 |
| ABHD2 | abhydrolase domain containing 2 | -0.0283495 |
| DNM2 | dynamin 2 | -0.0282075 |
| PTEN | phosphatase and tensin homolog | -0.0278359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.027361 |
| HLA-A | major histocompatibility complex, class I, A | -0.0267921 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0261289 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0261273 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0259334 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0255022 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0254334 |
| MT2A | metallothionein 2A | -0.0252487 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0249672 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0248767 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.024748 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0247221 |
| CALR | calreticulin | -0.0237516 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0234585 |
| ZNF395 | zinc finger protein 395 | -0.023356 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0232961 |
| PERP | PERP, TP53 apoptosis effector | -0.0232078 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0231901 |
| KLHL24 | kelch-like family member 24 | -0.0230004 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0226002 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0222718 |
| CANX | calnexin | -0.0222568 |
| OGA | O-GlcNAcase | -0.0221331 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0219331 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0218408 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0217623 |
| AGR2 | anterior gradient 2 | -0.0215553 |
| YEATS2 | YEATS domain containing 2 | -0.0215475 |
| HM13 | histocompatibility (minor) 13 | -0.0215469 |
| XPO1 | exportin 1 | -0.0215017 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0214902 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.021392 |
| RPL35A | ribosomal protein L35a | -0.0208739 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.020786 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0206453 |
| NUCB2 | nucleobindin 2 | -0.0202353 |
| EXOC1 | exocyst complex component 1 | -0.0200027 |
| AHNAK | AHNAK nucleoprotein | -0.0198366 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0196559 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0195266 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0195078 |
| RREB1 | ras responsive element binding protein 1 | -0.0194254 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0193366 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0193218 |
| CCNI | cyclin I | -0.0189668 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0188171 |
| ZNF652 | zinc finger protein 652 | -0.0187412 |
| HLA-E | major histocompatibility complex, class I, E | -0.0186153 |
| CENPF | centromere protein F, 350/400kDa | -0.0185667 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.018514 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.018464 |
| PDE8A | phosphodiesterase 8A | -0.0183922 |
| CTSD | cathepsin D | -0.0179827 |
| MEF2A | myocyte enhancer factor 2A | -0.0179526 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0179429 |
| TPM4 | tropomyosin 4 | -0.0179123 |
| IRS2 | insulin receptor substrate 2 | -0.0178823 |
| H3-3B | H3.3 histone B | -0.0178732 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0178701 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0178576 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0177951 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0175788 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0174812 |
| RB1 | retinoblastoma 1 | -0.0172711 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0171374 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0170645 |
| DIAPH3 | diaphanous-related formin 3 | -0.0169387 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0166703 |
| YTHDC1 | YTH domain containing 1 | -0.0166488 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0165635 |
| HLA-B | major histocompatibility complex, class I, B | -0.016527 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0165136 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.016449 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.0162691 |
| LASP1 | LIM and SH3 protein 1 | -0.016252 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0161571 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.0161334 |
