| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pemigatinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.195687 |
| SULF1 | sulfatase 1 | 0.136218 |
| FOXO1 | forkhead box O1 | 0.111293 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.110205 |
| LMO7 | LIM domain 7 | 0.0947506 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0838317 |
| AHNAK | AHNAK nucleoprotein | 0.0809639 |
| RASAL2 | RAS protein activator like 2 | 0.0779088 |
| MYOF | myoferlin | 0.0768429 |
| SMAD3 | SMAD family member 3 | 0.0727181 |
| DOK5 | docking protein 5 | 0.0634592 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.062194 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0615407 |
| NEK7 | NIMA-related kinase 7 | 0.0613044 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0609882 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0578115 |
| ITGA6 | integrin, alpha 6 | 0.0570264 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0547319 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0543294 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0538596 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0534856 |
| ASPH | aspartate beta-hydroxylase | 0.0531607 |
| CD44 | CD44 molecule (Indian blood group) | 0.0525998 |
| CTBP2 | C-terminal binding protein 2 | 0.0523797 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0519945 |
| RBM39 | RNA binding motif protein 39 | 0.0518709 |
| KIAA1217 | KIAA1217 | 0.0513163 |
| EFNA5 | ephrin-A5 | 0.0512219 |
| DOCK5 | dedicator of cytokinesis 5 | 0.051197 |
| PTK2 | protein tyrosine kinase 2 | 0.0510696 |
| FOXP1 | forkhead box P1 | 0.0494781 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0494292 |
| IFI44L | interferon-induced protein 44-like | 0.0469965 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0468143 |
| FNIP1 | folliculin interacting protein 1 | 0.0465657 |
| FAM107B | family with sequence similarity 107, member B | 0.0463368 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0456937 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0454103 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0449131 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.044527 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0439373 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0430111 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0427548 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0415312 |
| SIK3 | SIK family kinase 3 | 0.0411521 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0401671 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.039865 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0388863 |
| AOPEP | aminopeptidase O (putative) | 0.0388208 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0385393 |
| ECE1 | endothelin converting enzyme 1 | 0.038168 |
| MEF2C | myocyte enhancer factor 2C | 0.037839 |
| PLEC | plectin | 0.0377464 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.037584 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0375377 |
| KIAA1671 | KIAA1671 | 0.0372072 |
| MTSS1 | metastasis suppressor 1 | 0.0370048 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0369343 |
| CUL3 | cullin 3 | 0.0368447 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0368039 |
| PRELID2 | PRELI domain containing 2 | 0.0365127 |
| OSMR | oncostatin M receptor | 0.0361487 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0355437 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0352923 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0351171 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0350285 |
| ANO6 | anoctamin 6 | 0.034924 |
| EMP1 | epithelial membrane protein 1 | 0.0347938 |
| FLNA | filamin A, alpha | 0.0345956 |
| CANX | calnexin | 0.0344864 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0343414 |
| JMJD1C | jumonji domain containing 1C | 0.0343201 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0342853 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0338 |
| PODXL | podocalyxin-like | 0.0337126 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0333377 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0331538 |
| UBC | ubiquitin C | 0.0331513 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0328379 |
| KLF12 | Kruppel-like factor 12 | 0.0327892 |
| CDK17 | cyclin-dependent kinase 17 | 0.0323851 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0322714 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.032213 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0321177 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0319674 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0316131 |
| SETD2 | SET domain containing 2 | 0.031069 |
| IL6ST | interleukin 6 signal transducer | 0.0310213 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.030894 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0307559 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0306305 |
| CALU | calumenin | 0.0301818 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0301035 |
| RNF217 | ring finger protein 217 | 0.0300204 |
| FLNB | filamin B, beta | 0.029821 |
| XPO1 | exportin 1 | 0.0296637 |
| EXOC6B | exocyst complex component 6B | 0.0294381 |
| ANXA2 | annexin A2 | 0.0291208 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0291109 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.029068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.199974 |
| MT2A | metallothionein 2A | -0.0928666 |
| CLU | clusterin | -0.0714953 |
| IGF2 | insulin-like growth factor 2 | -0.0661935 |
| RAI14 | retinoic acid induced 14 | -0.0543757 |
| RPS6 | ribosomal protein S6 | -0.0505147 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0485663 |
| RPL11 | ribosomal protein L11 | -0.0484007 |
| RPS8 | ribosomal protein S8 | -0.0410902 |
| MT1E | metallothionein 1E | -0.0410746 |
| NDRG1 | N-myc downstream regulated 1 | -0.039825 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.038265 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0379503 |
| RPL27A | ribosomal protein L27a | -0.0366301 |
| MT1X | metallothionein 1X | -0.0354244 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0351751 |
| B2M | beta-2-microglobulin | -0.0347774 |
| RPL35A | ribosomal protein L35a | -0.0346255 |
| RPS13 | ribosomal protein S13 | -0.0327559 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0309122 |
| RPL37A | ribosomal protein L37a | -0.0302825 |
| RPS25 | ribosomal protein S25 | -0.0296454 |
| RPS19 | ribosomal protein S19 | -0.0278648 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0277688 |
| RPLP2 | ribosomal protein, large, P2 | -0.0257781 |
| RPL37 | ribosomal protein L37 | -0.0254549 |
| RPL36 | ribosomal protein L36 | -0.0251619 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0247702 |
| RPS29 | ribosomal protein S29 | -0.0242358 |
| CERT1 | ceramide transporter 1 | -0.0238053 |
| RPS21 | ribosomal protein S21 | -0.0232533 |
| RPS11 | ribosomal protein S11 | -0.0230109 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0229889 |
| FTL | ferritin, light polypeptide | -0.0227059 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0226489 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0225689 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0224532 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0221953 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0218415 |
| CSNK1E | casein kinase 1, epsilon | -0.021794 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0212043 |
| RPLP0 | ribosomal protein, large, P0 | -0.0204791 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0201839 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0201002 |
| EGFR | epidermal growth factor receptor | -0.0199687 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0198944 |
| GUK1 | guanylate kinase 1 | -0.0195939 |
| RPL9 | ribosomal protein L9 | -0.019459 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0194522 |
| TMSB10 | thymosin beta 10 | -0.0192768 |
| S100A11 | S100 calcium binding protein A11 | -0.0192435 |
| RPS20 | ribosomal protein S20 | -0.0190546 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0189535 |
| HMGA1 | high mobility group AT-hook 1 | -0.0188723 |
| RPL36A | ribosomal protein L36a | -0.0187113 |
| UTRN | utrophin | -0.0186567 |
| DSPP | dentin sialophosphoprotein | -0.0184912 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | -0.0184596 |
| RPS24 | ribosomal protein S24 | -0.0183186 |
| INSIG2 | insulin induced gene 2 | -0.0182875 |
| S100A9 | S100 calcium binding protein A9 | -0.0182342 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0179418 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0177837 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0176369 |
| RPS23 | ribosomal protein S23 | -0.0174825 |
| NECTIN4 | nectin cell adhesion molecule 4 | -0.0174274 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0173353 |
| H1-0 | H1.0 linker histone | -0.0173058 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0172726 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0172435 |
| PTMA | prothymosin, alpha | -0.0170666 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0170033 |
| RPLP1 | ribosomal protein, large, P1 | -0.0169878 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0168896 |
| HLA-B | major histocompatibility complex, class I, B | -0.0168569 |
| RPS12 | ribosomal protein S12 | -0.0168527 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0167676 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0167145 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0165653 |
| TPM4 | tropomyosin 4 | -0.0164408 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.016432 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0162108 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0158807 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0157167 |
| SSH2 | slingshot protein phosphatase 2 | -0.0156204 |
| DENND4C | DENN/MADD domain containing 4C | -0.0155319 |
| CD99 | CD99 molecule | -0.01548 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0154027 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0153974 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0151617 |
| S100A10 | S100 calcium binding protein A10 | -0.0151239 |
| DENND1A | DENN/MADD domain containing 1A | -0.0151201 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0150961 |
| PRSS23 | protease, serine, 23 | -0.014893 |
| RPL30 | ribosomal protein L30 | -0.014861 |
| PFN1 | profilin 1 | -0.0148503 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.014827 |
| RPL31 | ribosomal protein L31 | -0.0148112 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0147873 |
| RPL35 | ribosomal protein L35 | -0.0144968 |
