| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pemigatinib_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.136212 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.134197 |
| LMO7 | LIM domain 7 | 0.0920993 |
| SIK3 | SIK family kinase 3 | 0.0780347 |
| GDA | guanine deaminase | 0.0706534 |
| JMJD1C | jumonji domain containing 1C | 0.0664982 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0645751 |
| ANXA1 | annexin A1 | 0.0636235 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0598372 |
| COBL | cordon-bleu WH2 repeat protein | 0.0591758 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0580862 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0516654 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0498227 |
| B2M | beta-2-microglobulin | 0.0496673 |
| CLTC | clathrin, heavy chain (Hc) | 0.0494922 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0478445 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0477599 |
| RAB7A | RAB7A, member RAS oncogene family | 0.047595 |
| TES | testin LIM domain protein | 0.0450111 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0442378 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0438934 |
| TXNRD1 | thioredoxin reductase 1 | 0.0432068 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0430099 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.04229 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0407025 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0405101 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0403756 |
| KLHL29 | kelch-like family member 29 | 0.0401703 |
| COG5 | component of oligomeric golgi complex 5 | 0.039839 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0394558 |
| RNF213 | ring finger protein 213 | 0.0392325 |
| FRMD5 | FERM domain containing 5 | 0.0390663 |
| ETNK1 | ethanolamine kinase 1 | 0.0387704 |
| TMEM106B | transmembrane protein 106B | 0.0386869 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0379491 |
| TMC5 | transmembrane channel-like 5 | 0.0377655 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0374188 |
| TXNIP | thioredoxin interacting protein | 0.0368942 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0354197 |
| INO80 | INO80 complex subunit | 0.0351846 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0351526 |
| FNIP1 | folliculin interacting protein 1 | 0.0349598 |
| AHR | aryl hydrocarbon receptor | 0.0348825 |
| DENND4A | DENN/MADD domain containing 4A | 0.0346236 |
| MYOF | myoferlin | 0.0344588 |
| EZR | ezrin | 0.0343666 |
| SQSTM1 | sequestosome 1 | 0.0343054 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.034302 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0339703 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0335537 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0332519 |
| VMP1 | vacuole membrane protein 1 | 0.0330631 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0329961 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0328076 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0327412 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0326656 |
| MYO1E | myosin IE | 0.0325879 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.032366 |
| PTEN | phosphatase and tensin homolog | 0.0322197 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0319762 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.0314679 |
| AGR3 | anterior gradient 3 | 0.0312127 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0308216 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0306963 |
| CCNH | cyclin H | 0.0303791 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0302614 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0299071 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.029904 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0297664 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0295715 |
| SLMAP | sarcolemma associated protein | 0.0295107 |
| GPHN | gephyrin | 0.0293127 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0292228 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0291092 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0283868 |
| NFIB | nuclear factor I/B | 0.0280315 |
| ATF5 | activating transcription factor 5 | 0.0279638 |
| KRT17 | keratin 17, type I | 0.0279334 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0277285 |
| COPA | coatomer protein complex, subunit alpha | 0.0277138 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.027386 |
| WDR43 | WD repeat domain 43 | 0.027241 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0271687 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0268889 |
| HKDC1 | hexokinase domain containing 1 | 0.0266929 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0266924 |
| BRD2 | bromodomain containing 2 | 0.026582 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0265692 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0265351 |
| PCM1 | pericentriolar material 1 | 0.0260953 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0260812 |
| HM13 | histocompatibility (minor) 13 | 0.0258443 |
| USP53 | ubiquitin specific peptidase 53 | 0.0256815 |
| RNF111 | ring finger protein 111 | 0.0254608 |
| ZNF148 | zinc finger protein 148 | 0.0253014 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0252763 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0251265 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0251035 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.025091 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0250842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.244713 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.241898 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.171979 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.102843 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0883094 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0815321 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0706362 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0674532 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0611654 |
| CDK6 | cyclin-dependent kinase 6 | -0.0578466 |
| TNIK | TRAF2 and NCK interacting kinase | -0.053149 |
| TMSB10 | thymosin beta 10 | -0.0521092 |
| EHBP1 | EH domain binding protein 1 | -0.050873 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0501831 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0482244 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0481542 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0448289 |
| KRT18 | keratin 18, type I | -0.0427251 |
| CANX | calnexin | -0.0425897 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0417711 |
| NDRG1 | N-myc downstream regulated 1 | -0.0398246 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0398015 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0396553 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0395741 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0392388 |
| RRBP1 | ribosome binding protein 1 | -0.0386165 |
| LAMB3 | laminin, beta 3 | -0.0378591 |
| HLA-C | major histocompatibility complex, class I, C | -0.0372869 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0369668 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0364988 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358519 |
| PRSS3 | protease, serine, 3 | -0.035717 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0351602 |
| FLNB | filamin B, beta | -0.0350427 |
| PTK2 | protein tyrosine kinase 2 | -0.0348163 |
| PRKCA | protein kinase C, alpha | -0.0340082 |
| AUTS2 | autism susceptibility candidate 2 | -0.0337411 |
| TFRC | transferrin receptor | -0.0334431 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0331231 |
| ACTG1 | actin gamma 1 | -0.0329951 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0322742 |
| WDR45B | WD repeat domain 45B | -0.0320054 |
| AHNAK | AHNAK nucleoprotein | -0.031873 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0315884 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.031538 |
| RBM47 | RNA binding motif protein 47 | -0.0304502 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0304046 |
| S100A6 | S100 calcium binding protein A6 | -0.0302868 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.030197 |
| CTBP2 | C-terminal binding protein 2 | -0.0298434 |
| DYM | dymeclin | -0.0297471 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0295429 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0287544 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0283581 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0281297 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0279808 |
| SULF2 | sulfatase 2 | -0.0279768 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0278748 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0276581 |
| ONECUT3 | one cut homeobox 3 | -0.0274732 |
| RIN2 | Ras and Rab interactor 2 | -0.0274618 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0272302 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0270078 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0269687 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0267431 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0266528 |
| RBM39 | RNA binding motif protein 39 | -0.02659 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0265389 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0263665 |
| CALR | calreticulin | -0.0263293 |
| HLA-A | major histocompatibility complex, class I, A | -0.0262976 |
| PGK1 | phosphoglycerate kinase 1 | -0.0259592 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0256879 |
| AGR2 | anterior gradient 2 | -0.0255261 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0252113 |
| TNS4 | tensin 4 | -0.0243127 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0240989 |
| INSIG1 | insulin induced gene 1 | -0.0240951 |
| PKP4 | plakophilin 4 | -0.0240454 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.023984 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.023947 |
| ETV6 | ets variant 6 | -0.0238511 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0234009 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0233421 |
| KLK10 | kallikrein-related peptidase 10 | -0.0232077 |
| DSG2 | desmoglein 2 | -0.0231034 |
| RPL34 | ribosomal protein L34 | -0.023001 |
| PKM | pyruvate kinase, muscle | -0.0228195 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.022717 |
| LAMA4 | laminin, alpha 4 | -0.0226358 |
| KLF13 | Kruppel-like factor 13 | -0.0226231 |
| KRT8 | keratin 8, type II | -0.0225808 |
| FMN1 | formin 1 | -0.0225065 |
| ANLN | anillin, actin binding protein | -0.0224682 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0224525 |
| SDC4 | syndecan 4 | -0.0219058 |
| ZFHX3 | zinc finger homeobox 3 | -0.0215874 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0213881 |
| CUX1 | cut-like homeobox 1 | -0.0211831 |
| RPS3 | ribosomal protein S3 | -0.0211561 |
