| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pemigatinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.237943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.159153 |
| VIM | vimentin | 0.152923 |
| LOX | lysyl oxidase | 0.120051 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.115326 |
| GRB10 | growth factor receptor-bound protein 10 | 0.114035 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.108617 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.1001 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0938634 |
| CDH13 | cadherin 13 | 0.0933611 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0926288 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0910992 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0785879 |
| LDHA | lactate dehydrogenase A | 0.0763823 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0725021 |
| CD44 | CD44 molecule (Indian blood group) | 0.0612947 |
| TNNC1 | troponin C type 1 (slow) | 0.0611719 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.057971 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0570517 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0559571 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0557206 |
| NAV2 | neuron navigator 2 | 0.055629 |
| FTL | ferritin, light polypeptide | 0.0547837 |
| ATXN1 | ataxin 1 | 0.0483899 |
| ARSJ | arylsulfatase family, member J | 0.0468642 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0468227 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0466079 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0464235 |
| PLIN2 | perilipin 2 | 0.0462453 |
| RPL23 | ribosomal protein L23 | 0.0448374 |
| CLIC4 | chloride intracellular channel 4 | 0.0445394 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0438035 |
| CA12 | carbonic anhydrase XII | 0.0430999 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0430982 |
| ATP13A3 | ATPase type 13A3 | 0.0421196 |
| CLMP | CXADR-like membrane protein | 0.041339 |
| ANGPTL4 | angiopoietin-like 4 | 0.0400896 |
| FAM193A | family with sequence similarity 193, member A | 0.0395226 |
| DTNA | dystrobrevin, alpha | 0.0394306 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0391537 |
| RPL35A | ribosomal protein L35a | 0.0390744 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0387686 |
| NRG1 | neuregulin 1 | 0.0386698 |
| SQSTM1 | sequestosome 1 | 0.0384401 |
| FAM107B | family with sequence similarity 107, member B | 0.0377229 |
| B2M | beta-2-microglobulin | 0.0377133 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.037261 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0372014 |
| G0S2 | G0/G1 switch 2 | 0.037107 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0369917 |
| SFTPA2 | surfactant protein A2 | 0.0365225 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0352282 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0349923 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0349753 |
| CDCP1 | CUB domain containing protein 1 | 0.0348637 |
| TPI1 | triosephosphate isomerase 1 | 0.034419 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0343158 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0340071 |
| ENO1 | enolase 1, (alpha) | 0.0337695 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0335359 |
| GLIS3 | GLIS family zinc finger 3 | 0.0332275 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0327816 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0326135 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0321487 |
| ECE1 | endothelin converting enzyme 1 | 0.0318134 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0315349 |
| NRP1 | neuropilin 1 | 0.0313439 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0311338 |
| ITGAV | integrin, alpha V | 0.0305674 |
| FHL2 | four and a half LIM domains 2 | 0.030243 |
| NAV1 | neuron navigator 1 | 0.0298753 |
| FMNL2 | formin-like 2 | 0.0297981 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0297628 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0296669 |
| EFNA5 | ephrin-A5 | 0.0296601 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.0295035 |
| AUTS2 | autism susceptibility candidate 2 | 0.0293126 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0291078 |
| EMP1 | epithelial membrane protein 1 | 0.0290068 |
| PCBP2 | poly(rC) binding protein 2 | 0.0285505 |
| PKM | pyruvate kinase, muscle | 0.0284743 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0281938 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.0281383 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0272012 |
| FNIP1 | folliculin interacting protein 1 | 0.0269068 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0266465 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0266333 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0264907 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0264226 |
| WWOX | WW domain containing oxidoreductase | 0.0259411 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0257131 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0256345 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.025435 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0252532 |
| DENND4A | DENN/MADD domain containing 4A | 0.025175 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0251654 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0250728 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0249011 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0247697 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0247464 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.1082 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0741366 |
| RBM39 | RNA binding motif protein 39 | -0.0714845 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0684602 |
| FAM20C | family with sequence similarity 20, member C | -0.0680798 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0642576 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0619084 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0603797 |
| USP34 | ubiquitin specific peptidase 34 | -0.059944 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0567168 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0523519 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0510327 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0507249 |
| GLCCI1 | glucocorticoid induced 1 | -0.0504821 |
| MECOM | MDS1 and EVI1 complex locus | -0.0497652 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0495458 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0494865 |
| PRELID2 | PRELI domain containing 2 | -0.0485707 |
| GPC6 | glypican 6 | -0.0476698 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0467536 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.045459 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0450503 |
| OGA | O-GlcNAcase | -0.0444473 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0442153 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0424091 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.04224 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0411477 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0404428 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0401373 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0398606 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0398196 |
| FN1 | fibronectin 1 | -0.0397408 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0390218 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0380177 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0368913 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.035851 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0356383 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0347896 |
| VCL | vinculin | -0.0345441 |
| NHSL1 | NHS-like 1 | -0.0343092 |
| HDLBP | high density lipoprotein binding protein | -0.032998 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0329894 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0329039 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0328495 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.032374 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0323616 |
| RIGI | RNA sensor RIG-I | -0.032058 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0313521 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0308617 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0308121 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.030598 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0305961 |
| IL6ST | interleukin 6 signal transducer | -0.0303308 |
| MCL1 | myeloid cell leukemia 1 | -0.0301453 |
| SIK3 | SIK family kinase 3 | -0.030103 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0300337 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0297809 |
| YLPM1 | YLP motif containing 1 | -0.0297731 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0296126 |
| ZNF609 | zinc finger protein 609 | -0.0294724 |
| MYOF | myoferlin | -0.0294115 |
| MX2 | MX dynamin-like GTPase 2 | -0.0289016 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0288388 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0288354 |
| SP100 | SP100 nuclear antigen | -0.0287669 |
| PRR16 | proline rich 16 | -0.028596 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0284054 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.027747 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0275444 |
| XPO1 | exportin 1 | -0.0275099 |
| KIF5B | kinesin family member 5B | -0.0269806 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0268512 |
| DIAPH2 | diaphanous-related formin 2 | -0.0267813 |
| SVIL | supervillin | -0.0266953 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0264439 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0264198 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0264106 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0263007 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026238 |
| OXR1 | oxidation resistance 1 | -0.0261946 |
| LUZP1 | leucine zipper protein 1 | -0.0260938 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0258064 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0257829 |
| WASF2 | WAS protein family, member 2 | -0.0256532 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0255439 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0255158 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0254878 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0254873 |
| NGLY1 | N-glycanase 1 | -0.0254835 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0253055 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0251819 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0251122 |
| ZFR | zinc finger RNA binding protein | -0.0250672 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0250615 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0248286 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0247382 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0247044 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246642 |
| RASA2 | RAS p21 protein activator 2 | -0.0246333 |
| ACTN4 | actinin, alpha 4 | -0.0246055 |
