| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pemigatinib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.107108 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0893801 |
| HDAC9 | histone deacetylase 9 | 0.0851905 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0805692 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0805385 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0780196 |
| ITGAV | integrin, alpha V | 0.0731184 |
| PLPP1 | phospholipid phosphatase 1 | 0.0693033 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0681759 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.063621 |
| TENM3 | teneurin transmembrane protein 3 | 0.0604109 |
| COL5A2 | collagen, type V, alpha 2 | 0.0604073 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0569836 |
| CDH19 | cadherin 19, type 2 | 0.053216 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0520652 |
| PEG10 | paternally expressed 10 | 0.0515289 |
| PLCB4 | phospholipase C, beta 4 | 0.048636 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.0472786 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0470368 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0457474 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0457306 |
| TRIM2 | tripartite motif containing 2 | 0.0440977 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0433809 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0430806 |
| DST | dystonin | 0.0422404 |
| NEBL | nebulette | 0.0418814 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0417586 |
| GPC4 | glypican 4 | 0.0412581 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0410594 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0403883 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0397401 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0395858 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0390782 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0372267 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0371477 |
| PHIP | pleckstrin homology domain interacting protein | 0.0369345 |
| MYO9A | myosin IXA | 0.0360718 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0360093 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0358877 |
| PCDH7 | protocadherin 7 | 0.0357014 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0355025 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0352481 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0348762 |
| NTM | neurotrimin | 0.0346194 |
| TXNRD1 | thioredoxin reductase 1 | 0.0342252 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0341589 |
| MED13L | mediator complex subunit 13-like | 0.0330515 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0329843 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0322284 |
| COL3A1 | collagen, type III, alpha 1 | 0.0320057 |
| OLA1 | Obg-like ATPase 1 | 0.0311026 |
| ANXA5 | annexin A5 | 0.0304364 |
| FAM168A | family with sequence similarity 168, member A | 0.0302375 |
| DOCK7 | dedicator of cytokinesis 7 | 0.030042 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0294542 |
| MECOM | MDS1 and EVI1 complex locus | 0.0293516 |
| KIF5B | kinesin family member 5B | 0.0293161 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0293103 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0292996 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0291871 |
| PDGFC | platelet derived growth factor C | 0.0284727 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0284717 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0284677 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0281313 |
| FOXP2 | forkhead box P2 | 0.0278386 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0278239 |
| GOLT1A | golgi transport 1A | 0.0275706 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0271054 |
| CDK13 | cyclin-dependent kinase 13 | 0.0267325 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0261381 |
| TNPO1 | transportin 1 | 0.0260342 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0259215 |
| ENO1 | enolase 1, (alpha) | 0.0258088 |
| RHOA | ras homolog family member A | 0.0256867 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0254207 |
| RBM20 | RNA binding motif protein 20 | 0.0253807 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0251784 |
| SBF2 | SET binding factor 2 | 0.0249792 |
| H1-0 | H1.0 linker histone | 0.0249103 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.024872 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0248325 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0247454 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0245894 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0245817 |
| RTN4 | reticulon 4 | 0.0245724 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0245546 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0244558 |
| SRP54 | signal recognition particle 54kDa | 0.024422 |
| JMJD1C | jumonji domain containing 1C | 0.0244026 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.024322 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0241977 |
| PREPL | prolyl endopeptidase-like | 0.0240632 |
| GPHRA | golgi pH regulator A | 0.0240569 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0238448 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0237141 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0236765 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 | 0.023645 |
| YEATS2 | YEATS domain containing 2 | 0.0235684 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0235097 |
| SNX6 | sorting nexin 6 | 0.0233665 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0894001 |
| CADM2 | cell adhesion molecule 2 | -0.0559436 |
| LRRC4C | leucine rich repeat containing 4C | -0.047309 |
| PTMA | prothymosin, alpha | -0.0459077 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0447481 |
| TMSB10 | thymosin beta 10 | -0.0334116 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0329652 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0289513 |
| SPAG9 | sperm associated antigen 9 | -0.0288195 |
| NRG1 | neuregulin 1 | -0.0281135 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0279905 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0279403 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0276283 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0265172 |
| RPL37 | ribosomal protein L37 | -0.026149 |
| PCDH9 | protocadherin 9 | -0.0254818 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0250099 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0243058 |
| DMD | dystrophin | -0.0242488 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0234614 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0233266 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0221139 |
| PARD3B | par-3 family cell polarity regulator beta | -0.021745 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0207052 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0205307 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0205293 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.020511 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0201419 |
| RPS13 | ribosomal protein S13 | -0.0200977 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0199669 |
| GNAS | GNAS complex locus | -0.0199305 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0198501 |
| HDAC8 | histone deacetylase 8 | -0.0194584 |
| RPL19 | ribosomal protein L19 | -0.0190377 |
| CAVIN1 | caveolae associated protein 1 | -0.018824 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0187548 |
| ATXN2 | ataxin 2 | -0.0185527 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0184834 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.018101 |
| SIK2 | salt-inducible kinase 2 | -0.0180724 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0180432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0177625 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0175266 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0175066 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0174518 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0173263 |
| RBM33 | RNA binding motif protein 33 | -0.0168572 |
| ACTG1 | actin gamma 1 | -0.0168273 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | -0.016691 |
| OGA | O-GlcNAcase | -0.016614 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0165403 |
| ENAH | enabled homolog (Drosophila) | -0.0164217 |
| RPL15 | ribosomal protein L15 | -0.0162974 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0160539 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0159569 |
| URI1 | URI1, prefoldin-like chaperone | -0.0159286 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0158311 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.015731 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.0156775 |
| TOP1 | topoisomerase (DNA) I | -0.0156566 |
| FST | follistatin | -0.0155638 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0155564 |
| HMGB1 | high mobility group box 1 | -0.0155302 |
| RPS3 | ribosomal protein S3 | -0.0154626 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0154401 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0152872 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0152036 |
| CTBP2 | C-terminal binding protein 2 | -0.015133 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0150829 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0147807 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0147655 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0147584 |
| CALR | calreticulin | -0.0147004 |
| THOC2 | THO complex 2 | -0.0146573 |
| RPS27A | ribosomal protein S27a | -0.0145669 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0145458 |
| RIGI | RNA sensor RIG-I | -0.0145366 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0145202 |
| RPS25 | ribosomal protein S25 | -0.0143915 |
| TPD52 | tumor protein D52 | -0.0143039 |
| RPL38 | ribosomal protein L38 | -0.0142997 |
| GOLGB1 | golgin B1 | -0.0142841 |
| EXOC6B | exocyst complex component 6B | -0.0140816 |
| EVI5 | ecotropic viral integration site 5 | -0.0140515 |
| CENPE | centromere protein E, 312kDa | -0.0140103 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0139893 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0139482 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0138927 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0137812 |
| RPL11 | ribosomal protein L11 | -0.0137677 |
| FOXJ3 | forkhead box J3 | -0.0135694 |
| DENND4C | DENN/MADD domain containing 4C | -0.0135583 |
| UBN2 | ubinuclein 2 | -0.0135363 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0134768 |
| RFPL4B | ret finger protein-like 4B | -0.0134658 |
| UBXN4 | UBX domain protein 4 | -0.0134655 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0133153 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0132308 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0132169 |
| CABIN1 | calcineurin binding protein 1 | -0.0131892 |
