| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pemigatinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.191729 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.127589 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0633278 |
| EZR | ezrin | 0.0599111 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0480921 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0476424 |
| PKM | pyruvate kinase, muscle | 0.0448766 |
| PCNX1 | pecanex 1 | 0.0435658 |
| TCF12 | transcription factor 12 | 0.0417039 |
| EGFR | epidermal growth factor receptor | 0.0416681 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.041077 |
| GSE1 | Gse1 coiled-coil protein | 0.0405143 |
| TMEM65 | transmembrane protein 65 | 0.0399971 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0381273 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0372275 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0364893 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0363237 |
| AHI1 | Abelson helper integration site 1 | 0.0357822 |
| PDGFC | platelet derived growth factor C | 0.0335014 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0329846 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0326371 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0314614 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0312987 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0312235 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0309301 |
| ATP9B | ATPase, class II, type 9B | 0.0296906 |
| GPHN | gephyrin | 0.0292311 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0289614 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0289425 |
| POTEF | POTE ankyrin domain family, member F | 0.0285972 |
| RBM26 | RNA binding motif protein 26 | 0.0283901 |
| IRS1 | insulin receptor substrate 1 | 0.0279338 |
| BRD2 | bromodomain containing 2 | 0.027917 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.027873 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0274665 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0273574 |
| MED13L | mediator complex subunit 13-like | 0.0271161 |
| CORO1C | coronin, actin binding protein, 1C | 0.0271044 |
| USP47 | ubiquitin specific peptidase 47 | 0.0263878 |
| GLI2 | GLI family zinc finger 2 | 0.0263284 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0263273 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0260562 |
| ANXA1 | annexin A1 | 0.0256044 |
| ZNF638 | zinc finger protein 638 | 0.0255158 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0252984 |
| FOXP1 | forkhead box P1 | 0.0248224 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.024751 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0242068 |
| NBAS | neuroblastoma amplified sequence | 0.0238208 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0231687 |
| SBF2 | SET binding factor 2 | 0.0229752 |
| ZNF438 | zinc finger protein 438 | 0.0228252 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0228225 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0226451 |
| ZNF608 | zinc finger protein 608 | 0.0222912 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0221185 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0221174 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0220508 |
| CUL5 | cullin 5 | 0.0220327 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.0219422 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0219043 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0217682 |
| SPPL3 | signal peptide peptidase like 3 | 0.0217666 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0217146 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0217108 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.021601 |
| KLC1 | kinesin light chain 1 | 0.0215842 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0215483 |
| MEMO1 | mediator of cell motility 1 | 0.0215136 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0212261 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0211711 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0210071 |
| FLNB | filamin B, beta | 0.0209279 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 0.0209067 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0208061 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0206664 |
| FNIP1 | folliculin interacting protein 1 | 0.0205675 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0205615 |
| ADAR | adenosine deaminase, RNA-specific | 0.0204898 |
| FAM168B | family with sequence similarity 168, member B | 0.0204856 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0203622 |
| BPTF | bromodomain PHD finger transcription factor | 0.0202275 |
| ATM | ATM serine/threonine kinase | 0.020213 |
| TRRAP | transformation/transcription domain-associated protein | 0.0201194 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0201002 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0199291 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0198499 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0197782 |
| FAT1 | FAT atypical cadherin 1 | 0.0196662 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0196435 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | 0.0195854 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0195003 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0194477 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0194383 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0193173 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0192048 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0190923 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0190675 |
| MLIP | muscular LMNA-interacting protein | 0.0190596 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0188546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.315432 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.27168 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.119797 |
| RPS8 | ribosomal protein S8 | -0.10982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.107534 |
| RPS6 | ribosomal protein S6 | -0.105445 |
| BMP10 | bone morphogenetic protein 10 | -0.0987175 |
| ACTG1 | actin gamma 1 | -0.0856378 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0819626 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0761253 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0744459 |
| TMSB4X | thymosin beta 4, X-linked | -0.0689819 |
| RPL26 | ribosomal protein L26 | -0.0621998 |
| RPLP1 | ribosomal protein, large, P1 | -0.0589138 |
| RPL19 | ribosomal protein L19 | -0.0563173 |
| RPL12 | ribosomal protein L12 | -0.055553 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.054957 |
| RPL7A | ribosomal protein L7a | -0.0545036 |
| RPL34 | ribosomal protein L34 | -0.0543858 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0532645 |
| RPL35A | ribosomal protein L35a | -0.0514829 |
| RPL13A | ribosomal protein L13a | -0.0509501 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0466122 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0449549 |
| RPLP2 | ribosomal protein, large, P2 | -0.0447212 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0439238 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0436967 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0432027 |
| ENO1 | enolase 1, (alpha) | -0.0428625 |
| RPL9 | ribosomal protein L9 | -0.0428211 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0427727 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0415289 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0405544 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.040405 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0393314 |
| RPS12 | ribosomal protein S12 | -0.0387735 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0387225 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.038427 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0378266 |
| RPS27A | ribosomal protein S27a | -0.0372965 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.037221 |
| RPS19 | ribosomal protein S19 | -0.0368746 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0368144 |
| RPL23 | ribosomal protein L23 | -0.0363256 |
| CUX1 | cut-like homeobox 1 | -0.0362041 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0361839 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0353299 |
| RPS23 | ribosomal protein S23 | -0.0351719 |
| RPLP0 | ribosomal protein, large, P0 | -0.035097 |
| RPS3 | ribosomal protein S3 | -0.0350627 |
| TPM4 | tropomyosin 4 | -0.0347373 |
| RPL5 | ribosomal protein L5 | -0.0339867 |
| RPL31 | ribosomal protein L31 | -0.0338489 |
| RPS25 | ribosomal protein S25 | -0.0335658 |
| RPS13 | ribosomal protein S13 | -0.0334004 |
| RPL35 | ribosomal protein L35 | -0.033247 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0327947 |
| RPL37A | ribosomal protein L37a | -0.0327063 |
| GNAS | GNAS complex locus | -0.0326883 |
| RPL7 | ribosomal protein L7 | -0.0326007 |
| RPS24 | ribosomal protein S24 | -0.0324156 |
| RPL37 | ribosomal protein L37 | -0.0321825 |
| RPL8 | ribosomal protein L8 | -0.0319066 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0316735 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0314637 |
| TMSB10 | thymosin beta 10 | -0.0313416 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0304754 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0296753 |
| RPL36 | ribosomal protein L36 | -0.0296223 |
| RACK1 | receptor for activated C kinase 1 | -0.0293676 |
| RPS10 | ribosomal protein S10 | -0.0286713 |
| RPL10A | ribosomal protein L10a | -0.0286142 |
| RPL36A | ribosomal protein L36a | -0.0286109 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0281889 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0280329 |
| RPL4 | ribosomal protein L4 | -0.027982 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0279692 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0278834 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277997 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.027458 |
| RPS16 | ribosomal protein S16 | -0.0264731 |
| S100A9 | S100 calcium binding protein A9 | -0.0264002 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0263802 |
| RPL30 | ribosomal protein L30 | -0.026259 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0260889 |
| S100A10 | S100 calcium binding protein A10 | -0.02569 |
| RPS11 | ribosomal protein S11 | -0.0256134 |
| RPS14 | ribosomal protein S14 | -0.0256091 |
| RPS29 | ribosomal protein S29 | -0.0255341 |
| RPS2 | ribosomal protein S2 | -0.0253211 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.025313 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0252106 |
| VIM | vimentin | -0.0250969 |
| RPS21 | ribosomal protein S21 | -0.0250959 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0250693 |
| FN1 | fibronectin 1 | -0.0245092 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0242493 |
| CCND1 | cyclin D1 | -0.0241098 |
| FTL | ferritin, light polypeptide | -0.0239869 |
| RPS20 | ribosomal protein S20 | -0.0235994 |
