| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pemigatinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.316785 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.178448 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.159652 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.134292 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0756323 |
| FN1 | fibronectin 1 | 0.0684883 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0682554 |
| PRSS23 | protease, serine, 23 | 0.0581859 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0551962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0536509 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0462549 |
| RNF145 | ring finger protein 145 | 0.0452046 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0450009 |
| RAI14 | retinoic acid induced 14 | 0.0422345 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.041632 |
| COL5A1 | collagen, type V, alpha 1 | 0.0407372 |
| B2M | beta-2-microglobulin | 0.0404693 |
| NRP1 | neuropilin 1 | 0.0404014 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0381756 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0380734 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0365063 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0353063 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0352712 |
| TMEM165 | transmembrane protein 165 | 0.0351866 |
| MAP1B | microtubule-associated protein 1B | 0.0335933 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0326975 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0292844 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292445 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0287143 |
| PGK1 | phosphoglycerate kinase 1 | 0.0283803 |
| ECE1 | endothelin converting enzyme 1 | 0.0281965 |
| LOX | lysyl oxidase | 0.0276463 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0271725 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0269204 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0267004 |
| ARRDC3 | arrestin domain containing 3 | 0.0266634 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0259888 |
| LAMB1 | laminin, beta 1 | 0.0251811 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.024771 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0247363 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0244129 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.023573 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0235341 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0234785 |
| VIM | vimentin | 0.0232292 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0228474 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0225677 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0224057 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0223976 |
| APP | amyloid beta (A4) precursor protein | 0.0223213 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0222411 |
| SEC24D | SEC24 family member D | 0.0218782 |
| STC1 | stanniocalcin 1 | 0.0216984 |
| PTK2 | protein tyrosine kinase 2 | 0.0216306 |
| PTN | pleiotrophin | 0.0215284 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.021524 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0214293 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0214141 |
| MTPN | myotrophin | 0.0211835 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0211191 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0207926 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.020746 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0206439 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0206353 |
| HLA-C | major histocompatibility complex, class I, C | 0.0198298 |
| RDX | radixin | 0.0196046 |
| FUS | FUS RNA binding protein | 0.0195134 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0193237 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0192532 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0190759 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0190442 |
| USO1 | USO1 vesicle transport factor | 0.0189354 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0185646 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0183912 |
| AHNAK | AHNAK nucleoprotein | 0.0182387 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0179188 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.017898 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0177995 |
| MYO10 | myosin X | 0.0176633 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0175722 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0175071 |
| CLINT1 | clathrin interactor 1 | 0.0175004 |
| TMEM263 | transmembrane protein 263 | 0.0174805 |
| TANK | TRAF family member-associated NFKB activator | 0.0174454 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0170559 |
| PRELID2 | PRELI domain containing 2 | 0.0170486 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0168302 |
| DCTN4 | dynactin 4 (p62) | 0.0167908 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0167903 |
| LDHA | lactate dehydrogenase A | 0.0167814 |
| TXNIP | thioredoxin interacting protein | 0.0167147 |
| YEATS2 | YEATS domain containing 2 | 0.0167042 |
| ANXA1 | annexin A1 | 0.0166296 |
| VEGFA | vascular endothelial growth factor A | 0.016459 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0163471 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0162229 |
| ACLY | ATP citrate lyase | 0.0160231 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0158127 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0157507 |
| ATP13A3 | ATPase type 13A3 | 0.0156776 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0663373 |
| CDH13 | cadherin 13 | -0.0431841 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0289751 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.027449 |
| SEPTIN7 | septin 7 | -0.0251972 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.024728 |
| NAV2 | neuron navigator 2 | -0.0241391 |
| MT2A | metallothionein 2A | -0.0241218 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0203798 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0202312 |
| IL6 | interleukin 6 | -0.0201323 |
| EGFR | epidermal growth factor receptor | -0.0200201 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0197314 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0187067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0185621 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0185373 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0182484 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0179952 |
| NKTR | natural killer cell triggering receptor | -0.0175447 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0175051 |
| NF1 | neurofibromin 1 | -0.0174553 |
| VCL | vinculin | -0.0166303 |
| ASPH | aspartate beta-hydroxylase | -0.0165674 |
| RBM25 | RNA binding motif protein 25 | -0.0164774 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0164181 |
| TMSB10 | thymosin beta 10 | -0.0164079 |
| GOLGA4 | golgin A4 | -0.0163638 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0163446 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0161567 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0161458 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0160534 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0160265 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0155219 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0152596 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0150759 |
| LAMB3 | laminin, beta 3 | -0.0149614 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0149237 |
| ACTG1 | actin gamma 1 | -0.0148575 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0145858 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0143199 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0142928 |
| RPL19 | ribosomal protein L19 | -0.0142739 |
| RCOR1 | REST corepressor 1 | -0.014165 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0141606 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.014079 |
| FNBP4 | formin binding protein 4 | -0.0139624 |
| FNIP1 | folliculin interacting protein 1 | -0.0139065 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0138731 |
| TMEM41B | transmembrane protein 41B | -0.0138483 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0138361 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0136916 |
| EGR1 | early growth response 1 | -0.0136639 |
| XPO1 | exportin 1 | -0.0136526 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0136033 |
| HIP1 | huntingtin interacting protein 1 | -0.0135553 |
| PHF3 | PHD finger protein 3 | -0.0135018 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0134138 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.013391 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0133591 |
| VEGFC | vascular endothelial growth factor C | -0.0133 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0132904 |
| HPCAL1 | hippocalcin-like 1 | -0.0132646 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0132458 |
| RPLP1 | ribosomal protein, large, P1 | -0.0131685 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0131672 |
| RAB31 | RAB31, member RAS oncogene family | -0.0130557 |
| INHBA | inhibin, beta A | -0.0130306 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0130099 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.012958 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0129508 |
| RBM6 | RNA binding motif protein 6 | -0.0129487 |
| PCNX4 | pecanex 4 | -0.0128 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0127686 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.012751 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0126647 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0126635 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0126577 |
| RPL34 | ribosomal protein L34 | -0.0126555 |
| FRMD6 | FERM domain containing 6 | -0.0126402 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0125128 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0125106 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0124479 |
| RPL5 | ribosomal protein L5 | -0.0123083 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0123033 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0122559 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0121997 |
| RPS12 | ribosomal protein S12 | -0.0120631 |
| CCDC88A | coiled-coil domain containing 88A | -0.0120594 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0118592 |
| OLA1 | Obg-like ATPase 1 | -0.0117652 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0117025 |
| SQSTM1 | sequestosome 1 | -0.0116807 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0115294 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0114698 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0114425 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0113903 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0113864 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0112576 |
| ANLN | anillin, actin binding protein | -0.0111498 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0111473 |
