| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pemigatinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pemigatinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0637502 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0625267 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0564746 |
| RBM25 | RNA binding motif protein 25 | 0.0551904 |
| PKM | pyruvate kinase, muscle | 0.0543997 |
| ATP13A3 | ATPase type 13A3 | 0.0504998 |
| VIM | vimentin | 0.0501286 |
| MED13 | mediator complex subunit 13 | 0.0471018 |
| B2M | beta-2-microglobulin | 0.0465077 |
| RBM39 | RNA binding motif protein 39 | 0.0457181 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0439778 |
| CD44 | CD44 molecule (Indian blood group) | 0.0437026 |
| TPI1 | triosephosphate isomerase 1 | 0.0432078 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0430228 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0410291 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.039627 |
| RPS13 | ribosomal protein S13 | 0.0393239 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0390184 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0386647 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0379445 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0369709 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0362197 |
| HDAC9 | histone deacetylase 9 | 0.0361299 |
| TBK1 | TANK-binding kinase 1 | 0.0361204 |
| RPL23 | ribosomal protein L23 | 0.0361037 |
| ANXA1 | annexin A1 | 0.0359112 |
| EXOC6B | exocyst complex component 6B | 0.0358151 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0357716 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0356356 |
| RPL35A | ribosomal protein L35a | 0.0350991 |
| RUNX1 | runt-related transcription factor 1 | 0.0347199 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0346018 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.034575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0339197 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0338087 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0337274 |
| EMP1 | epithelial membrane protein 1 | 0.0337051 |
| TMEM87A | transmembrane protein 87A | 0.0335718 |
| SVIL | supervillin | 0.0330889 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0323103 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0319009 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0316832 |
| MIS18BP1 | MIS18 binding protein 1 | 0.031531 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0315289 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0314647 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.031162 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0310151 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0306199 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0301423 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0296676 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295766 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0295486 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.02939 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.029357 |
| SEPTIN9 | septin 9 | 0.0292847 |
| NUP153 | nucleoporin 153kDa | 0.0292272 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0291144 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.029043 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0288624 |
| RAB31 | RAB31, member RAS oncogene family | 0.0286456 |
| TLK1 | tousled-like kinase 1 | 0.02837 |
| EVI5 | ecotropic viral integration site 5 | 0.0283119 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0281463 |
| SON | SON DNA binding protein | 0.0279515 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0278199 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0277923 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0276143 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0275839 |
| NEK7 | NIMA-related kinase 7 | 0.0275718 |
| ANGPTL4 | angiopoietin-like 4 | 0.0275101 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0273504 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0273076 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0272888 |
| DTNA | dystrobrevin, alpha | 0.0272679 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0272229 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0268273 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.02651 |
| RPL11 | ribosomal protein L11 | 0.0264563 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0264544 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0263868 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0262153 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.026206 |
| HLA-B | major histocompatibility complex, class I, B | 0.0259957 |
| RCOR1 | REST corepressor 1 | 0.0259922 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0259565 |
| ITSN2 | intersectin 2 | 0.0257627 |
| RPLP2 | ribosomal protein, large, P2 | 0.0257185 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0256531 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0255605 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.025512 |
| BARD1 | BRCA1 associated RING domain 1 | 0.0254478 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0254207 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253729 |
| MKI67 | marker of proliferation Ki-67 | 0.0253006 |
| ETV6 | ets variant 6 | 0.0252985 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0251863 |
| ZNF207 | zinc finger protein 207 | 0.02511 |
| IL6ST | interleukin 6 signal transducer | 0.0250014 |
| RAD51B | RAD51 paralog B | 0.0249461 |
| RPL9 | ribosomal protein L9 | 0.0245237 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.168364 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.164716 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0884956 |
| INTS6 | integrator complex subunit 6 | -0.0882717 |
| HMGA2 | high mobility group AT-hook 2 | -0.0611787 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0519512 |
| MYOF | myoferlin | -0.0515725 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0501529 |
| MAP1B | microtubule-associated protein 1B | -0.0484433 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0470758 |
| ARFGEF3 | ARFGEF family member 3 | -0.0470096 |
| GPC6 | glypican 6 | -0.0456009 |
| ACTG1 | actin gamma 1 | -0.0450794 |
| ASPH | aspartate beta-hydroxylase | -0.0446891 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0441308 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0440686 |
| RAI14 | retinoic acid induced 14 | -0.0439902 |
| SDC4 | syndecan 4 | -0.0436467 |
| PGK1 | phosphoglycerate kinase 1 | -0.0425119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0416072 |
| CALU | calumenin | -0.0412006 |
| PRELID2 | PRELI domain containing 2 | -0.0406737 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0405994 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0396725 |
| PTMA | prothymosin, alpha | -0.0396299 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0390732 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0381006 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0379911 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.037414 |
| GOLGB1 | golgin B1 | -0.0373341 |
| NDRG1 | N-myc downstream regulated 1 | -0.0370166 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0367691 |
| TMEM263 | transmembrane protein 263 | -0.0365 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0358644 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0357973 |
| FLNA | filamin A, alpha | -0.035285 |
| CANX | calnexin | -0.0352632 |
| AHNAK | AHNAK nucleoprotein | -0.0352221 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.034973 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0342911 |
| GNAS | GNAS complex locus | -0.0341658 |
| TMEM123 | transmembrane protein 123 | -0.0339585 |
| ATXN1 | ataxin 1 | -0.0338887 |
| SMAD2 | SMAD family member 2 | -0.0333256 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0323669 |
| PODXL | podocalyxin-like | -0.0321255 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0319659 |
| YBX1 | Y box binding protein 1 | -0.0317261 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0313795 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0312735 |
| HM13 | histocompatibility (minor) 13 | -0.0312005 |
| FLNB | filamin B, beta | -0.0311702 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0308277 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0306392 |
| MCL1 | myeloid cell leukemia 1 | -0.0304802 |
| FBXO11 | F-box protein 11 | -0.0303245 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0297755 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0296981 |
| ADIPOR2 | adiponectin receptor 2 | -0.029459 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0293487 |
| GPATCH2L | G patch domain containing 2-like | -0.0292577 |
| GOLGA3 | golgin A3 | -0.0291158 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0286378 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0282098 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0281961 |
| RRBP1 | ribosome binding protein 1 | -0.0281755 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0281638 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0279628 |
| SETX | senataxin | -0.0275882 |
| TGFB1 | transforming growth factor, beta 1 | -0.0275605 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.026942 |
| FN1 | fibronectin 1 | -0.0268565 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0266182 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0265713 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0265667 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0265456 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0264926 |
| MBTD1 | mbt domain containing 1 | -0.0261661 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0261042 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0260831 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0259126 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0257533 |
| MYO10 | myosin X | -0.0257527 |
| ACER3 | alkaline ceramidase 3 | -0.0255761 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0255617 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0255313 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0253867 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0252724 |
| ABR | active BCR-related | -0.0252353 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0252001 |
| USP15 | ubiquitin specific peptidase 15 | -0.0249815 |
| COG6 | component of oligomeric golgi complex 6 | -0.0246707 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0245815 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0244059 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0243851 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0241402 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0233006 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0231671 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0231313 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0231263 |
