Pemphigoid Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

400 genes co-occuring with the disease Pemphigoid in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
COL17A1 collagen, type XVII, alpha 1 4.0
DST dystonin 4.0
DSG3 desmoglein 3 3.328
DSG1 desmoglein 1 3.315
LAMA3 laminin, alpha 3 2.799
DPP4 dipeptidyl-peptidase 4 2.709
PPL periplakin 2.682
PLEC plectin 2.618
EVPL envoplakin 2.599
IL5 interleukin 5 2.435
IL4 interleukin 4 2.428
IL31 interleukin 31 2.419
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.407
IL17A interleukin 17A 2.376
IL13 interleukin 13 2.374
CD4 CD4 molecule 2.351
DSP desmoplakin 2.345
C3 complement component 3 2.302
PDCD1 programmed cell death 1 2.275
CCL11 chemokine (C-C motif) ligand 11 2.271
TNF tumor necrosis factor 2.237
CD274 CD274 molecule 2.234
IFNG interferon, gamma 2.208
RNASE3 ribonuclease, RNase A family, 3 2.195
CD8A CD8a molecule 2.172
IL6 interleukin 6 2.171
KRT3 keratin 3, type II 2.139
KRT12 keratin 12, type I 2.138
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.137
IL1B interleukin 1, beta 2.129
COL18A1 collagen, type XVIII, alpha 1 2.12
ITGB4 integrin, beta 4 2.113
A2ML1 alpha-2-macroglobulin-like 1 2.103
DSC3 desmocollin 3 2.1
FCGRT Fc fragment of IgG, receptor, transporter, alpha 2.093
CXCL8 chemokine (C-X-C motif) ligand 8 2.092
ELANE elastase, neutrophil expressed 2.073
MMP9 matrix metallopeptidase 9 2.067
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.044
IL10 interleukin 10 2.043
IL2 interleukin 2 2.02
IL1A interleukin 1, alpha 2.017
TSLP thymic stromal lymphopoietin 2.011
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.01
C5AR1 complement component 5a receptor 1 1.999
IL4R interleukin 4 receptor 1.997
CCL17 chemokine (C-C motif) ligand 17 1.955
TGFB1 transforming growth factor, beta 1 1.946
CCL26 chemokine (C-C motif) ligand 26 1.929
DSC1 desmocollin 1 1.925
ITGA6 integrin, alpha 6 1.891
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1.886
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.856
FOXP3 forkhead box P3 1.845
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.837
IL22 interleukin 22 1.833
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.818
FN1 fibronectin 1 1.811
FLG2 filaggrin family member 2 1.811
FLG filaggrin 1.804
EPPK1 epiplakin 1 1.799
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.779
IL31RA interleukin 31 receptor A 1.778
CXCL10 chemokine (C-X-C motif) ligand 10 1.747
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.739
CRP C-reactive protein, pentraxin-related 1.73
EPX eosinophil peroxidase 1.727
PLG plasminogen 1.72
IL3 interleukin 3 1.72
IL5RA interleukin 5 receptor, alpha 1.717
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.716
C5AR2 complement component 5a receptor 2 1.707
RNF103 ring finger protein 103 1.707
ALB albumin 1.707
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.688
C1S complement component 1, s subcomponent 1.683
PKP3 plakophilin 3 1.68
CCL5 chemokine (C-C motif) ligand 5 1.679
EGF epidermal growth factor 1.674
MPO myeloperoxidase 1.674
DSC2 desmocollin 2 1.672
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.669
CCR3 chemokine (C-C motif) receptor 3 1.666
ANXA9 annexin A9 1.656
IFNA1 interferon, alpha 1 1.655
TPO thyroid peroxidase 1.654
TAC1 tachykinin, precursor 1 1.654
ACE angiotensin I converting enzyme 1.648
IVL involucrin 1.646
COL7A1 collagen, type VII, alpha 1 1.642
CD40LG CD40 ligand 1.641
IL33 interleukin 33 1.64
KRT14 keratin 14, type I 1.637
DPP8 dipeptidyl-peptidase 8 1.632
INS insulin 1.619
ICAM1 intercellular adhesion molecule 1 1.617
CD80 CD80 molecule 1.614
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.612
CD40 CD40 molecule, TNF receptor superfamily member 5 1.606
NGF nerve growth factor (beta polypeptide) 1.596
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.592
KRT4 keratin 4, type II 1.585
C4A complement component 4A (Rodgers blood group) 1.574
FIP1L1 factor interacting with PAPOLA and CPSF1 1.572
KRT13 keratin 13, type I 1.564
POSTN periostin, osteoblast specific factor 1.562
CFP complement factor properdin 1.561
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.561
CMA1 chymase 1, mast cell 1.559
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.554
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 1.55
F3 coagulation factor III (thromboplastin, tissue factor) 1.549
IL9 interleukin 9 1.549
OSMR oncostatin M receptor 1.543
KRT15 keratin 15, type I 1.542
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.536
TGM2 transglutaminase 2 1.534
DPP9 dipeptidyl-peptidase 9 1.534
SYK spleen tyrosine kinase 1.533
PXDN peroxidasin 1.519
PXDNL peroxidasin-like 1.518
DSG4 desmoglein 4 1.504
FGF7 fibroblast growth factor 7 1.493
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.492
TACR1 tachykinin receptor 1 1.492
LAMB3 laminin, beta 3 1.489
CXCL9 chemokine (C-X-C motif) ligand 9 1.488
PAX6 paired box 6 1.486
PRTN3 proteinase 3 1.484
CCL24 chemokine (C-C motif) ligand 24 1.48
CD19 CD19 molecule 1.479
MRGPRX2 MAS-related GPR, member X2 1.471
TOR1A torsin family 1, member A (torsin A) 1.469
HLA-B major histocompatibility complex, class I, B 1.468
JAK1 Janus kinase 1 1.467
IL15 interleukin 15 1.46
CCL2 chemokine (C-C motif) ligand 2 1.459
CD151 CD151 molecule (Raph blood group) 1.456
SIGLEC8 sialic acid binding Ig-like lectin 8 1.454
LTF lactotransferrin 1.45
CD86 CD86 molecule 1.447
IL17F interleukin 17F 1.44
CD28 CD28 molecule 1.436
HRH4 histamine receptor H4 1.436
LACRT lacritin 1.435
BTK Bruton agammaglobulinemia tyrosine kinase 1.427
MUC16 mucin 16, cell surface associated 1.425
CAMP cathelicidin antimicrobial peptide 1.422
LAMC2 laminin, gamma 2 1.421
CCL3 chemokine (C-C motif) ligand 3 1.42
CCL4 chemokine (C-C motif) ligand 4 1.419
KRT5 keratin 5, type II 1.416
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 1.412
RAG2 recombination activating gene 2 1.41
CLC Charcot-Leyden crystal galectin 1.408
CRLF2 cytokine receptor-like factor 2 1.407
PDCD1LG2 programmed cell death 1 ligand 2 1.4
FCAR Fc fragment of IgA receptor 1.399
CCL22 chemokine (C-C motif) ligand 22 1.397
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.396
IL18 interleukin 18 1.396
IL16 interleukin 16 1.395
G6PD glucose-6-phosphate dehydrogenase 1.394
IL17RA interleukin 17 receptor A 1.393
POMC proopiomelanocortin 1.39
CCL13 chemokine (C-C motif) ligand 13 1.389
LAMA4 laminin, alpha 4 1.389
NID1 nidogen 1 1.389
SELE selectin E 1.389
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.387
CCL20 chemokine (C-C motif) ligand 20 1.384
ELN elastin 1.384
GCG glucagon 1.38
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.378
F8 coagulation factor VIII, procoagulant component 1.375
CSF3 colony stimulating factor 3 (granulocyte) 1.371
TRIM21 tripartite motif containing 21 1.37
FASLG Fas ligand (TNF superfamily, member 6) 1.37
PDE4A phosphodiesterase 4A, cAMP-specific 1.367
SELL selectin L 1.365
IL7 interleukin 7 1.36
F2 coagulation factor II (thrombin) 1.357
CD1C CD1c molecule 1.352
MMP3 matrix metallopeptidase 3 1.351
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.35
IFNA2 interferon, alpha 2 1.349
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.349
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 1.348
MUC7 mucin 7, secreted 1.347
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.343
CD163 CD163 molecule 1.341
TG thyroglobulin 1.337
CD1B CD1b molecule 1.336
IL36RN interleukin 36 receptor antagonist 1.334
TGM3 transglutaminase 3 1.332
EGFR epidermal growth factor receptor 1.332
C4B complement component 4B (Chido blood group) 1.332
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.331
CXCR3 chemokine (C-X-C motif) receptor 3 1.327
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 1.322
GNLY granulysin 1.314
ADAM10 ADAM metallopeptidase domain 10 1.313
PTPRC protein tyrosine phosphatase, receptor type, C 1.308
IL24 interleukin 24 1.308
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.307
CXCR5 chemokine (C-X-C motif) receptor 5 1.304
MUC1 mucin 1, cell surface associated 1.303
KERA keratocan 1.303
CTSG cathepsin G 1.297
MMP2 matrix metallopeptidase 2 1.296
CD1D CD1d molecule 1.295
VTN vitronectin 1.295
TLR2 toll-like receptor 2 1.294
HLA-A major histocompatibility complex, class I, A 1.294
PTGDR2 prostaglandin D2 receptor 2 1.293
MUC4 mucin 4, cell surface associated 1.293
TLR9 toll-like receptor 9 1.292
HLA-C major histocompatibility complex, class I, C 1.291
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.29
KRT1 keratin 1, type II 1.289
ICOS inducible T-cell co-stimulator 1.288
CD69 CD69 molecule 1.286
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.285
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.283
CD1E CD1e molecule 1.279
HSPG2 heparan sulfate proteoglycan 2 1.278
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.278
KITLG KIT ligand 1.275
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.271
CCRL2 chemokine (C-C motif) receptor-like 2 1.269
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.269
CD1A CD1a molecule 1.268
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.268
LTB4R leukotriene B4 receptor 1.266
KRT19 keratin 19, type I 1.264
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 1.264
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.263
PRF1 perforin 1 (pore forming protein) 1.259
CCR6 chemokine (C-C motif) receptor 6 1.258
TLR4 toll-like receptor 4 1.255
FGF10 fibroblast growth factor 10 1.254
MMP1 matrix metallopeptidase 1 1.252
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 1.25
FGF22 fibroblast growth factor 22 1.249
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.249
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.248
SSB Sjogren syndrome antigen B (autoantigen La) 1.248
FGF16 fibroblast growth factor 16 1.247
KRT10 keratin 10, type I 1.242
MATN1 matrilin 1, cartilage matrix protein 1.241
MMP8 matrix metallopeptidase 8 1.239
FGF6 fibroblast growth factor 6 1.238
FGF20 fibroblast growth factor 20 1.236
FGF17 fibroblast growth factor 17 1.234
FGF2 fibroblast growth factor 2 (basic) 1.231
FGF18 fibroblast growth factor 18 1.23
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.23
FGF5 fibroblast growth factor 5 1.23
CXCL13 chemokine (C-X-C motif) ligand 13 1.228
ADAM9 ADAM metallopeptidase domain 9 1.226
TCF15 transcription factor 15 (basic helix-loop-helix) 1.226
FGF3 fibroblast growth factor 3 1.225
NLRP3 NLR family, pyrin domain containing 3 1.223
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.222
FGF9 fibroblast growth factor 9 1.221
TLR7 toll-like receptor 7 1.218
TGFB2 transforming growth factor, beta 2 1.217
SPINK5 serine peptidase inhibitor, Kazal type 5 1.216
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.216
FGF8 fibroblast growth factor 8 (androgen-induced) 1.215
FGF4 fibroblast growth factor 4 1.215
CD5 CD5 molecule 1.212
CARD14 caspase recruitment domain family, member 14 1.207
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.206
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.205
C5 complement component 5 1.203
MBL2 mannose-binding lectin (protein C) 2, soluble 1.201
VCAM1 vascular cell adhesion molecule 1 1.2
TPMT thiopurine S-methyltransferase 1.197
IFNA5 interferon, alpha 5 1.196
CD46 CD46 molecule, complement regulatory protein 1.196
CD27 CD27 molecule 1.193
IFNA4 interferon, alpha 4 1.192
GATA3 GATA binding protein 3 1.189
IFNA16 interferon, alpha 16 1.188
IFNA7 interferon, alpha 7 1.187
IFNA14 interferon, alpha 14 1.187
IFNA21 interferon, alpha 21 1.187
IFNA10 interferon, alpha 10 1.187
IFNA6 interferon, alpha 6 1.186
HRH1 histamine receptor H1 1.186
IFNA8 interferon, alpha 8 1.186
CXCL11 chemokine (C-X-C motif) ligand 11 1.185
IFNA13 interferon, alpha 13 1.184
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.181
IFNA17 interferon, alpha 17 1.179
MACF1 microtubule-actin crosslinking factor 1 1.179
KNG1 kininogen 1 1.176
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.175
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.175
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.174
ADAM17 ADAM metallopeptidase domain 17 1.172
IL7R interleukin 7 receptor 1.169
JAK2 Janus kinase 2 1.165
TIMP1 TIMP metallopeptidase inhibitor 1 1.164
CD59 CD59 molecule, complement regulatory protein 1.163
GIP gastric inhibitory polypeptide 1.163
PKP1 plakophilin 1 1.163
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.162
IFNB1 interferon, beta 1, fibroblast 1.16
MMP12 matrix metallopeptidase 12 1.159
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.159
VIP vasoactive intestinal peptide 1.158
TGM1 transglutaminase 1 1.158
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.157
LAG3 lymphocyte-activation gene 3 1.157
JAK3 Janus kinase 3 1.146
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.143
IL2RA interleukin 2 receptor, alpha 1.143
CD44 CD44 molecule (Indian blood group) 1.143
CXCL5 chemokine (C-X-C motif) ligand 5 1.143
TGFA transforming growth factor, alpha 1.141
LTA lymphotoxin alpha 1.14
IL1R1 interleukin 1 receptor, type I 1.14
CD200 CD200 molecule 1.137
IL26 interleukin 26 1.133
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.132
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.131
CXCR2 chemokine (C-X-C motif) receptor 2 1.13
CD207 CD207 molecule, langerin 1.128
GLP1R glucagon-like peptide 1 receptor 1.127
CCL1 chemokine (C-C motif) ligand 1 1.125
B2M beta-2-microglobulin 1.125
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.124
FERMT1 fermitin family member 1 1.123
LYN LYN proto-oncogene, Src family tyrosine kinase 1.121
MYD88 myeloid differentiation primary response 88 1.117
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.116
IL36R interleukin 36 receptor 1.114
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.113
AIRE autoimmune regulator 1.111
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.11
STAT1 signal transducer and activator of transcription 1, 91kDa 1.109
CD68 CD68 molecule 1.106
THBS1 thrombospondin 1 1.103
CXCL12 chemokine (C-X-C motif) ligand 12 1.103
CPA3 carboxypeptidase A3 (mast cell) 1.1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.1
IL25 interleukin 25 1.098
DHFR2 dihydrofolate reductase 2 1.098
CCN2 cellular communication network factor 2 1.093
LOC102723996 ICOS ligand 1.09
CARD9 caspase recruitment domain family, member 9 1.09
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 1.09
RBP3 retinol binding protein 3, interstitial 1.088
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.087
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.086
TYK2 tyrosine kinase 2 1.081
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 1.077
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 1.075
LCE3B late cornified envelope 3B 1.07
CXCR1 chemokine (C-X-C motif) receptor 1 1.069
CD63 CD63 molecule 1.065
CCR7 chemokine (C-C motif) receptor 7 1.064
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.062
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.06
CD52 CD52 molecule 1.059
VWF von Willebrand factor 1.058
COL4A6 collagen, type IV, alpha 6 1.052
TP53 tumor protein p53 1.052
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.051
CXCR4 chemokine (C-X-C motif) receptor 4 1.051
PF4 platelet factor 4 1.048
LPP LIM domain containing preferred translocation partner in lipoma 1.047
TBX21 T-box 21 1.046
GPR15 G protein-coupled receptor 15 1.045
IL17RC interleukin 17 receptor C 1.044
CD276 CD276 molecule 1.044
AQP5 aquaporin 5 1.042
CCL19 chemokine (C-C motif) ligand 19 1.041
C1R complement component 1, r subcomponent 1.036
CD34 CD34 molecule 1.034
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.034
IL36A interleukin 36, alpha 1.033
S100A7 S100 calcium binding protein A7 1.026
CPA4 carboxypeptidase A4 1.023
CCL7 chemokine (C-C motif) ligand 7 1.021
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.02
EXPH5 exophilin 5 1.02
DHFR dihydrofolate reductase 1.016
MASP2 mannan-binding lectin serine peptidase 2 1.014
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.013
MAPK3 mitogen-activated protein kinase 3 1.012
HSPA4 heat shock 70kDa protein 4 1.011
TSHR thyroid stimulating hormone receptor 1.009
WDR11 WD repeat domain 11 1.009
TYR tyrosinase 1.008
IL23R interleukin 23 receptor 1.004
IFIH1 interferon induced with helicase C domain 1 1.002
TLR3 toll-like receptor 3 1.0