| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.162718 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.13407 |
| PTMA | prothymosin, alpha | 0.116231 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0978725 |
| SQSTM1 | sequestosome 1 | 0.0866995 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0752337 |
| MT2A | metallothionein 2A | 0.0695331 |
| GOLGA4 | golgin A4 | 0.0691084 |
| NDRG1 | N-myc downstream regulated 1 | 0.0679722 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0617594 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0616593 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.061588 |
| PGK1 | phosphoglycerate kinase 1 | 0.0597153 |
| B2M | beta-2-microglobulin | 0.0595813 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0586155 |
| AUTS2 | autism susceptibility candidate 2 | 0.0583637 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0572993 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0558728 |
| MSI2 | musashi RNA-binding protein 2 | 0.0550456 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0538138 |
| TMSB4X | thymosin beta 4, X-linked | 0.0519177 |
| CSTB | cystatin B (stefin B) | 0.0508064 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0499855 |
| ZNF292 | zinc finger protein 292 | 0.0486901 |
| RND3 | Rho family GTPase 3 | 0.0476451 |
| MYOF | myoferlin | 0.0475691 |
| CD109 | CD109 molecule | 0.046795 |
| MSN | moesin | 0.045008 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0445663 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0437779 |
| RPS6 | ribosomal protein S6 | 0.0437392 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0436182 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0430553 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0427778 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0422626 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0422312 |
| TMSB10 | thymosin beta 10 | 0.0421005 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0415929 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0411015 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0408501 |
| GPC6 | glypican 6 | 0.0407295 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0407036 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0405932 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0403811 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0403452 |
| RAB18 | RAB18, member RAS oncogene family | 0.0402547 |
| FMNL2 | formin-like 2 | 0.0397996 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0397179 |
| HELZ | helicase with zinc finger | 0.0391534 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0381723 |
| TOX | thymocyte selection-associated high mobility group box | 0.0379726 |
| RPL37A | ribosomal protein L37a | 0.0368786 |
| CDH13 | cadherin 13 | 0.0367987 |
| SETD5 | SET domain containing 5 | 0.0366875 |
| FAM107B | family with sequence similarity 107, member B | 0.0366676 |
| ENO1 | enolase 1, (alpha) | 0.0359566 |
| ADM | adrenomedullin | 0.0357427 |
| RPS3 | ribosomal protein S3 | 0.0353884 |
| RPS12 | ribosomal protein S12 | 0.0352458 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0344423 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.034414 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0341915 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0340822 |
| DTNA | dystrobrevin, alpha | 0.0340495 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0340469 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0337978 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.033595 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0328407 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0323412 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0320972 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0318695 |
| FAM162A | family with sequence similarity 162, member A | 0.0314187 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0312507 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0311755 |
| CERT1 | ceramide transporter 1 | 0.0310151 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0305257 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0300592 |
| MATR3 | matrin 3 | 0.029951 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0299373 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0298933 |
| INSIG2 | insulin induced gene 2 | 0.0297183 |
| FTL | ferritin, light polypeptide | 0.0296748 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0296004 |
| RNF24 | ring finger protein 24 | 0.0295332 |
| SUCO | SUN domain containing ossification factor | 0.029478 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.029368 |
| RPL35A | ribosomal protein L35a | 0.0293116 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0290133 |
| RPLP1 | ribosomal protein, large, P1 | 0.0288039 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0280208 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0277004 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0276823 |
| FOSL1 | FOS-like antigen 1 | 0.027532 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0275005 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0274745 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.027397 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0273665 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0273152 |
| ATP13A3 | ATPase type 13A3 | 0.0272686 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0270055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.187975 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.16661 |
| LOX | lysyl oxidase | -0.165555 |
| AHNAK | AHNAK nucleoprotein | -0.125675 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.109474 |
| COL3A1 | collagen, type III, alpha 1 | -0.106026 |
| NAV1 | neuron navigator 1 | -0.103876 |
| FBN1 | fibrillin 1 | -0.090673 |
| PLAT | plasminogen activator, tissue | -0.0844694 |
| UBC | ubiquitin C | -0.0827267 |
| COL1A2 | collagen, type I, alpha 2 | -0.079775 |
| CD44 | CD44 molecule (Indian blood group) | -0.0725786 |
| GLIS3 | GLIS family zinc finger 3 | -0.0703842 |
| MAP1B | microtubule-associated protein 1B | -0.0671436 |
| MX2 | MX dynamin-like GTPase 2 | -0.0557761 |
| COL5A1 | collagen, type V, alpha 1 | -0.0529048 |
| COL5A2 | collagen, type V, alpha 2 | -0.0526474 |
| S100A10 | S100 calcium binding protein A10 | -0.0521421 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0492943 |
| HLA-B | major histocompatibility complex, class I, B | -0.0469357 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0407578 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0395527 |
| ANXA2 | annexin A2 | -0.0393956 |
| RAI14 | retinoic acid induced 14 | -0.0391558 |
| HLA-C | major histocompatibility complex, class I, C | -0.0383138 |
| EHBP1 | EH domain binding protein 1 | -0.0365648 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0357989 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0355522 |
| RNF213 | ring finger protein 213 | -0.0353471 |
| VCL | vinculin | -0.0352977 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0348543 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0339068 |
| TXNIP | thioredoxin interacting protein | -0.031569 |
| CDK6 | cyclin-dependent kinase 6 | -0.0308118 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0306457 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0299641 |
| CD99 | CD99 molecule | -0.0299149 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0294421 |
| RIGI | RNA sensor RIG-I | -0.0292017 |
| NPR2 | natriuretic peptide receptor 2 | -0.0290047 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0282958 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0275012 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0274511 |
| ZNF217 | zinc finger protein 217 | -0.0267861 |
| THBS2 | thrombospondin 2 | -0.0267363 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0266503 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0266046 |
| RRBP1 | ribosome binding protein 1 | -0.0264413 |
| HDLBP | high density lipoprotein binding protein | -0.026055 |
| OSMR | oncostatin M receptor | -0.025756 |
| CCND1 | cyclin D1 | -0.0249762 |
| SVIL | supervillin | -0.0247021 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0245739 |
| MAP4 | microtubule-associated protein 4 | -0.0244806 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0235632 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0234409 |
| GSE1 | Gse1 coiled-coil protein | -0.0234257 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0227676 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0226716 |
| PRELID2 | PRELI domain containing 2 | -0.0225003 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0222084 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0221963 |
| LAMB1 | laminin, beta 1 | -0.0221773 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0221708 |
| FUS | FUS RNA binding protein | -0.0219515 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.021736 |
| BPTF | bromodomain PHD finger transcription factor | -0.0217205 |
| SP100 | SP100 nuclear antigen | -0.0215837 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0215058 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0214868 |
| INTS6 | integrator complex subunit 6 | -0.0214505 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0213232 |
| VMP1 | vacuole membrane protein 1 | -0.0209499 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0208921 |
| PXDN | peroxidasin | -0.0207675 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.020645 |
| CEP112 | centrosomal protein 112kDa | -0.0206281 |
| MEIS2 | Meis homeobox 2 | -0.0205949 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0204843 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0203341 |
| ACTN4 | actinin, alpha 4 | -0.0202698 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201755 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0201417 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.020132 |
| FSTL1 | follistatin-like 1 | -0.0200967 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0194564 |
| TUBB | tubulin, beta class I | -0.0191551 |
| KIFAP3 | kinesin-associated protein 3 | -0.0189756 |
| NID1 | nidogen 1 | -0.018819 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0187808 |
| TRABD2B | TraB domain containing 2B | -0.0187664 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0187526 |
| SEPTIN9 | septin 9 | -0.0184673 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0184025 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0183528 |
| DIAPH3 | diaphanous-related formin 3 | -0.0183219 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.018314 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0181869 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0181722 |
| PARD3 | par-3 family cell polarity regulator | -0.0181183 |
