| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.115559 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0917493 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0903875 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0827674 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0757405 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0699247 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0665035 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0659291 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0654969 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.059475 |
| GASK1B | golgi associated kinase 1B | 0.0569842 |
| NEK7 | NIMA-related kinase 7 | 0.0568125 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0559741 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0525731 |
| TENM3 | teneurin transmembrane protein 3 | 0.0514602 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0506992 |
| TXNRD1 | thioredoxin reductase 1 | 0.0498809 |
| MED13L | mediator complex subunit 13-like | 0.0492666 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0469189 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0466965 |
| DST | dystonin | 0.0465881 |
| PCDH7 | protocadherin 7 | 0.0445817 |
| XPO1 | exportin 1 | 0.0444986 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0435087 |
| PUM2 | pumilio RNA-binding family member 2 | 0.043266 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0422074 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0420648 |
| SQSTM1 | sequestosome 1 | 0.0417062 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0411447 |
| PDGFC | platelet derived growth factor C | 0.0400101 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0397257 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0394046 |
| CLTC | clathrin, heavy chain (Hc) | 0.0390695 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0379803 |
| ZNF217 | zinc finger protein 217 | 0.0378882 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0376232 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0374741 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0374725 |
| THOC1 | THO complex 1 | 0.036824 |
| PGK1 | phosphoglycerate kinase 1 | 0.0365431 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0362431 |
| TNPO1 | transportin 1 | 0.0358726 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0357684 |
| NCKAP1 | NCK-associated protein 1 | 0.0354388 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0353751 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0351439 |
| CPOX | coproporphyrinogen oxidase | 0.033802 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0329885 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0329179 |
| RPLP0 | ribosomal protein, large, P0 | 0.0328763 |
| ATP11A | ATPase, class VI, type 11A | 0.0328608 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0327898 |
| MATR3 | matrin 3 | 0.0327747 |
| APP | amyloid beta (A4) precursor protein | 0.0327332 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0322107 |
| OXR1 | oxidation resistance 1 | 0.031594 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0311645 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0306279 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0305708 |
| PTMA | prothymosin, alpha | 0.0304785 |
| RPS12 | ribosomal protein S12 | 0.0298902 |
| SERINC1 | serine incorporator 1 | 0.0295954 |
| RPL3 | ribosomal protein L3 | 0.0293532 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0292852 |
| MGAT4C | MGAT4 family, member C | 0.0291779 |
| DSPP | dentin sialophosphoprotein | 0.0290477 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0289105 |
| CCN2 | cellular communication network factor 2 | 0.0287951 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0284857 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0283448 |
| RPS3 | ribosomal protein S3 | 0.0282939 |
| ECT2 | epithelial cell transforming 2 | 0.0282013 |
| CDK17 | cyclin-dependent kinase 17 | 0.0281382 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0280127 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0276079 |
| CDK6 | cyclin-dependent kinase 6 | 0.0274159 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0272878 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0268904 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0268826 |
| RPL4 | ribosomal protein L4 | 0.0265882 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0263922 |
| HMGB2 | high mobility group box 2 | 0.0262028 |
| KIF5B | kinesin family member 5B | 0.0258868 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0258243 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.025566 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0253854 |
| RPS27A | ribosomal protein S27a | 0.0253414 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0252368 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0251258 |
| CEP95 | centrosomal protein 95kDa | 0.0250245 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.024956 |
| IL6ST | interleukin 6 signal transducer | 0.0248508 |
| MMP12 | matrix metallopeptidase 12 | 0.0244566 |
| EPHA6 | EPH receptor A6 | 0.024288 |
| OGA | O-GlcNAcase | 0.0241113 |
| RACK1 | receptor for activated C kinase 1 | 0.0239462 |
| AHR | aryl hydrocarbon receptor | 0.0238543 |
| RPL19 | ribosomal protein L19 | 0.0237906 |
| MPG | N-methylpurine-DNA glycosylase | 0.0236485 |
| ETNK1 | ethanolamine kinase 1 | 0.0235792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211299 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.127194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.115009 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0974513 |
| EGR1 | early growth response 1 | -0.0972266 |
| VIM | vimentin | -0.0970273 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0921616 |
| HMGA2 | high mobility group AT-hook 2 | -0.0796216 |
| ACTG1 | actin gamma 1 | -0.0681462 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0666055 |
| EHBP1 | EH domain binding protein 1 | -0.0589701 |
| FTL | ferritin, light polypeptide | -0.0571552 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0535549 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0474186 |
| ADIPOR2 | adiponectin receptor 2 | -0.045137 |
| TUBA1B | tubulin, alpha 1b | -0.0406196 |
| PFN1 | profilin 1 | -0.0397421 |
| HMGA1 | high mobility group AT-hook 1 | -0.0384204 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0382704 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0370104 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0368735 |
| TPM4 | tropomyosin 4 | -0.0356994 |
| NHSL1 | NHS-like 1 | -0.0351559 |
| RPL35A | ribosomal protein L35a | -0.0350005 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0347739 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0346565 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0345876 |
| ANKRD17 | ankyrin repeat domain 17 | -0.032979 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0321246 |
| NAV3 | neuron navigator 3 | -0.0319491 |
| CUX1 | cut-like homeobox 1 | -0.0315853 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0310808 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0307892 |
| TMSB10 | thymosin beta 10 | -0.0306183 |
| USP34 | ubiquitin specific peptidase 34 | -0.0295442 |
| ZNF804A | zinc finger protein 804A | -0.0289115 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0286561 |
| RPS8 | ribosomal protein S8 | -0.028319 |
| ZNF638 | zinc finger protein 638 | -0.0282781 |
| BPTF | bromodomain PHD finger transcription factor | -0.0282393 |
| INTS6 | integrator complex subunit 6 | -0.0281173 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0280155 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0268256 |
| GCG | glucagon | -0.0268093 |
| LRRC23 | leucine rich repeat containing 23 | -0.0264191 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0261656 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.025193 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0249808 |
| ATXN2 | ataxin 2 | -0.0248944 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0247611 |
| POTEF | POTE ankyrin domain family, member F | -0.0245779 |
| JMJD1C | jumonji domain containing 1C | -0.0245737 |
| KSR2 | kinase suppressor of ras 2 | -0.0241973 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024039 |
| SETX | senataxin | -0.0235433 |
| GNAS | GNAS complex locus | -0.0232977 |
| MYADM | myeloid-associated differentiation marker | -0.0232059 |
| R3HDM2 | R3H domain containing 2 | -0.0226984 |
| CCND1 | cyclin D1 | -0.0224594 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0221472 |
| TBCA | tubulin folding cofactor A | -0.0221143 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0220641 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0219646 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0214718 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0214381 |
| GOLGB1 | golgin B1 | -0.0213328 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0212005 |
| UBXN4 | UBX domain protein 4 | -0.0211041 |
| FASN | fatty acid synthase | -0.021099 |
| BRD4 | bromodomain containing 4 | -0.0210801 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0210522 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0207603 |
| JUN | jun proto-oncogene | -0.0206831 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0205484 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0203333 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0201165 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0200322 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0200202 |
| ANKRD12 | ankyrin repeat domain 12 | -0.019882 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0197502 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0195945 |
| CMIP | c-Maf inducing protein | -0.0194781 |
| FADS2 | fatty acid desaturase 2 | -0.0194639 |
| S100A10 | S100 calcium binding protein A10 | -0.0185433 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0185332 |
| TUBA1C | tubulin, alpha 1c | -0.0181589 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.018039 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0177573 |
| ATN1 | atrophin 1 | -0.0176429 |
| UBAP2 | ubiquitin associated protein 2 | -0.0175785 |
| HLA-A | major histocompatibility complex, class I, A | -0.017559 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0173675 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0173388 |
| BRD2 | bromodomain containing 2 | -0.0172558 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0168926 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0167601 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0167544 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0166815 |
| ZNF207 | zinc finger protein 207 | -0.0165005 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0164754 |
