| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.120646 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0768005 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0741998 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0705376 |
| RNF149 | ring finger protein 149 | 0.0634903 |
| RUNX1 | runt-related transcription factor 1 | 0.0619336 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0612075 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0587648 |
| PTEN | phosphatase and tensin homolog | 0.0572871 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0524297 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0493339 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0469613 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0466443 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0454462 |
| DIAPH3 | diaphanous-related formin 3 | 0.0440363 |
| NDRG1 | N-myc downstream regulated 1 | 0.0433579 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0430579 |
| RNF43 | ring finger protein 43 | 0.041767 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0414184 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0400684 |
| ZNRF3 | zinc and ring finger 3 | 0.0394052 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0387908 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0385561 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0383611 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0369452 |
| SBF2 | SET binding factor 2 | 0.0367469 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0362703 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.034754 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0346459 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0339838 |
| NEBL | nebulette | 0.0338233 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.033742 |
| USP3 | ubiquitin specific peptidase 3 | 0.0335887 |
| UBAC2 | UBA domain containing 2 | 0.033501 |
| DENND4C | DENN/MADD domain containing 4C | 0.033443 |
| RNF145 | ring finger protein 145 | 0.0333859 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0324524 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0322058 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0320756 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0320419 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.032034 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0309532 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0303893 |
| PDE8A | phosphodiesterase 8A | 0.0299231 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0296857 |
| AOPEP | aminopeptidase O (putative) | 0.0295543 |
| ENO1 | enolase 1, (alpha) | 0.0286209 |
| ARRDC3 | arrestin domain containing 3 | 0.027785 |
| GRAMD2B | GRAM domain containing 2B | 0.0274302 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0273762 |
| OGA | O-GlcNAcase | 0.0273734 |
| XPO1 | exportin 1 | 0.0266538 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0263568 |
| STK39 | serine threonine kinase 39 | 0.0262686 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0262213 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0260795 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0260199 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0259542 |
| EHF | ets homologous factor | 0.0258065 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0252154 |
| CALR | calreticulin | 0.024806 |
| PRELID2 | PRELI domain containing 2 | 0.0247798 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0246501 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0245983 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0245638 |
| MKI67 | marker of proliferation Ki-67 | 0.0241812 |
| PTGR1 | prostaglandin reductase 1 | 0.0239181 |
| MATR3 | matrin 3 | 0.0238761 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0237138 |
| YEATS2 | YEATS domain containing 2 | 0.0236898 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0235559 |
| CLTC | clathrin, heavy chain (Hc) | 0.0235408 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0235261 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0234328 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0230674 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0230011 |
| RREB1 | ras responsive element binding protein 1 | 0.022806 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.022693 |
| HELZ | helicase with zinc finger | 0.0225521 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0225305 |
| FANCI | Fanconi anemia, complementation group I | 0.0224461 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0223744 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0220564 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0219662 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0216844 |
| SFXN1 | sideroflexin 1 | 0.0216084 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0214227 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0212202 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0211548 |
| GOLGA4 | golgin A4 | 0.0210791 |
| HYOU1 | hypoxia up-regulated 1 | 0.0210749 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0210514 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0208935 |
| SEC24D | SEC24 family member D | 0.0208707 |
| TRIM2 | tripartite motif containing 2 | 0.0208644 |
| INSIG1 | insulin induced gene 1 | 0.0207174 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0205993 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0205875 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.020534 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0205289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.203089 |
| ANXA2 | annexin A2 | -0.169566 |
| VCL | vinculin | -0.153456 |
| LMO7 | LIM domain 7 | -0.145272 |
| EGR1 | early growth response 1 | -0.135646 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.121268 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.109603 |
| RNF213 | ring finger protein 213 | -0.108856 |
| PHF3 | PHD finger protein 3 | -0.104512 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.100975 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.09404 |
| EZR | ezrin | -0.0932846 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0919125 |
| RIGI | RNA sensor RIG-I | -0.0881091 |
| PLSCR2 | phospholipid scramblase 2 | -0.0870763 |
| SP100 | SP100 nuclear antigen | -0.0840524 |
| PLSCR1 | phospholipid scramblase 1 | -0.08181 |
| MX1 | MX dynamin-like GTPase 1 | -0.0800491 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0790617 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0784062 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0778296 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0731317 |
| MAP7 | microtubule-associated protein 7 | -0.0731213 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0729063 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0708498 |
| AREG | amphiregulin | -0.0706082 |
| LYZ | lysozyme | -0.0698924 |
| POU2F2 | POU class 2 homeobox 2 | -0.0694626 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.064426 |
| MYO1E | myosin IE | -0.0632064 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0630527 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0629028 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0625844 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0625744 |
| MCL1 | myeloid cell leukemia 1 | -0.0604738 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0601299 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0599096 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0595715 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0594752 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0587539 |
| GOLGB1 | golgin B1 | -0.0573585 |
| MX2 | MX dynamin-like GTPase 2 | -0.0571092 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0569384 |
| TMC5 | transmembrane channel-like 5 | -0.0561988 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0560917 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0546416 |
| VMP1 | vacuole membrane protein 1 | -0.0532943 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0530757 |
| TNS4 | tensin 4 | -0.0530445 |
| TUFT1 | tuftelin 1 | -0.0526401 |
| PKM | pyruvate kinase, muscle | -0.0516862 |
| PERP | PERP, TP53 apoptosis effector | -0.0515399 |
| SMAD3 | SMAD family member 3 | -0.0510939 |
| XAF1 | XIAP associated factor 1 | -0.0510577 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0507141 |
| TJP1 | tight junction protein 1 | -0.0501068 |
| MCU | mitochondrial calcium uniporter | -0.048406 |
| PMP22 | peripheral myelin protein 22 | -0.0483856 |
| UBAP2 | ubiquitin associated protein 2 | -0.0479347 |
| MUC20 | mucin 20, cell surface associated | -0.0474281 |
| SQSTM1 | sequestosome 1 | -0.0461344 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0454945 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0451131 |
| HM13 | histocompatibility (minor) 13 | -0.0450964 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0450892 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0449977 |
| POF1B | premature ovarian failure, 1B | -0.0435969 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0424699 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0423264 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0417783 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.041458 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0413867 |
| EFNB2 | ephrin-B2 | -0.0413636 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0409558 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0399507 |
| LAMA4 | laminin, alpha 4 | -0.039773 |
| SDC4 | syndecan 4 | -0.0396265 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0395087 |
| ACTG1 | actin gamma 1 | -0.03856 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0380716 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0377004 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0369454 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0368335 |
| NUP98 | nucleoporin 98kDa | -0.0363883 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0360967 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0356943 |
| IRS2 | insulin receptor substrate 2 | -0.0354337 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0353854 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0353108 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0353004 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0352206 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0347206 |
| USP53 | ubiquitin specific peptidase 53 | -0.0346456 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0345813 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0339879 |
| HLA-B | major histocompatibility complex, class I, B | -0.0337975 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0332244 |
| NABP1 | nucleic acid binding protein 1 | -0.0329321 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0326258 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0324126 |
