| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Penfluridol_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ENO1 | enolase 1, (alpha) | 0.116292 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.112711 |
| MEF2A | myocyte enhancer factor 2A | 0.110224 |
| PGK1 | phosphoglycerate kinase 1 | 0.109079 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.1089 |
| MYOF | myoferlin | 0.0853167 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0835002 |
| STC1 | stanniocalcin 1 | 0.0818758 |
| TMSB4X | thymosin beta 4, X-linked | 0.0738056 |
| CANX | calnexin | 0.0734296 |
| KRT17 | keratin 17, type I | 0.0682872 |
| MSN | moesin | 0.0620186 |
| ASPH | aspartate beta-hydroxylase | 0.0584339 |
| LDHA | lactate dehydrogenase A | 0.057616 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0560242 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0549378 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0542418 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0518254 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0516799 |
| MTSS1 | metastasis suppressor 1 | 0.0498429 |
| ANXA1 | annexin A1 | 0.0491107 |
| KRT6A | keratin 6A, type II | 0.0469143 |
| CUL4B | cullin 4B | 0.0461824 |
| ANLN | anillin, actin binding protein | 0.0460834 |
| KIAA1217 | KIAA1217 | 0.0446415 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.044096 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0427922 |
| ARRDC3 | arrestin domain containing 3 | 0.0425922 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0420728 |
| CLU | clusterin | 0.0417621 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0407326 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0405669 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.040396 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0398429 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0396889 |
| SQSTM1 | sequestosome 1 | 0.039649 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0391953 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0385882 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0385008 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0384798 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0371916 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0367419 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0365537 |
| VCL | vinculin | 0.0365063 |
| SPAG9 | sperm associated antigen 9 | 0.035996 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0357161 |
| CENPF | centromere protein F, 350/400kDa | 0.035107 |
| GOLGA4 | golgin A4 | 0.0347403 |
| SLK | STE20-like kinase | 0.0347112 |
| KRT14 | keratin 14, type I | 0.034708 |
| FNIP1 | folliculin interacting protein 1 | 0.0333822 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0331693 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.032856 |
| FOXO1 | forkhead box O1 | 0.0324527 |
| SQLE | squalene epoxidase | 0.0322806 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321128 |
| OGA | O-GlcNAcase | 0.0320021 |
| ZNF292 | zinc finger protein 292 | 0.0319794 |
| DIAPH1 | diaphanous-related formin 1 | 0.0312857 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0312306 |
| FAM13A | family with sequence similarity 13, member A | 0.0310369 |
| MKI67 | marker of proliferation Ki-67 | 0.0309889 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0309644 |
| DST | dystonin | 0.030928 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0308649 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0308205 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0301068 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0297157 |
| DENND4C | DENN/MADD domain containing 4C | 0.0295981 |
| B2M | beta-2-microglobulin | 0.029378 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0286461 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0285862 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0283337 |
| APP | amyloid beta (A4) precursor protein | 0.0283063 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0280002 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0276319 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0276187 |
| RLF | rearranged L-myc fusion | 0.0271997 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0271267 |
| UBC | ubiquitin C | 0.0268491 |
| RPL11 | ribosomal protein L11 | 0.0267712 |
| COPA | coatomer protein complex, subunit alpha | 0.026678 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0259431 |
| PTK2 | protein tyrosine kinase 2 | 0.025855 |
| CALR | calreticulin | 0.0255619 |
| HELZ | helicase with zinc finger | 0.0255511 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0254847 |
| FAT1 | FAT atypical cadherin 1 | 0.0252735 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0252575 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0250624 |
| RNF145 | ring finger protein 145 | 0.0248134 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0246948 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246321 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245787 |
| SUCO | SUN domain containing ossification factor | 0.0242993 |
| NRCAM | neuronal cell adhesion molecule | 0.0239051 |
| PTEN | phosphatase and tensin homolog | 0.0238591 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0233668 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0231961 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0228471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0997763 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0974248 |
| LAMA5 | laminin, alpha 5 | -0.0731154 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0684174 |
| FLNB | filamin B, beta | -0.062549 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0589809 |
| TMSB10 | thymosin beta 10 | -0.0523763 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0446955 |
| RASAL2 | RAS protein activator like 2 | -0.04313 |
| IGF2 | insulin-like growth factor 2 | -0.042447 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0413375 |
| HM13 | histocompatibility (minor) 13 | -0.0381934 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0350165 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0347881 |
| EGR1 | early growth response 1 | -0.034578 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0315958 |
| RIN2 | Ras and Rab interactor 2 | -0.0308888 |
| RPS21 | ribosomal protein S21 | -0.0308646 |
| EFHD2 | EF-hand domain family, member D2 | -0.0307471 |
| S100A2 | S100 calcium binding protein A2 | -0.0298944 |
| MYADM | myeloid-associated differentiation marker | -0.0294621 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0290286 |
| GNAS | GNAS complex locus | -0.0287833 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0277202 |
| HMGA1 | high mobility group AT-hook 1 | -0.0274601 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0271362 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0258608 |
| TMEM263 | transmembrane protein 263 | -0.0257998 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0257616 |
| RPLP2 | ribosomal protein, large, P2 | -0.025606 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0255259 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0252691 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0250247 |
| IFI44L | interferon-induced protein 44-like | -0.0249844 |
| BCL2L1 | BCL2-like 1 | -0.0249298 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0244944 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0241621 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0239346 |
| RIGI | RNA sensor RIG-I | -0.0238859 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0231091 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0230929 |
| RPS19 | ribosomal protein S19 | -0.0230119 |
| PFN1 | profilin 1 | -0.0227554 |
| THBD | thrombomodulin | -0.0227128 |
| RRBP1 | ribosome binding protein 1 | -0.0222412 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0218674 |
| RPL35A | ribosomal protein L35a | -0.0216611 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0212571 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0210501 |
| HMGA2 | high mobility group AT-hook 2 | -0.0210204 |
| PRSS23 | protease, serine, 23 | -0.0209937 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0208178 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0204328 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0202243 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0199717 |
| MT2A | metallothionein 2A | -0.0198428 |
| RPL37A | ribosomal protein L37a | -0.0197424 |
| LUZP1 | leucine zipper protein 1 | -0.0194756 |
| RPL26 | ribosomal protein L26 | -0.0194756 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0190658 |
| TMEM165 | transmembrane protein 165 | -0.0188482 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0184843 |
| OSMR | oncostatin M receptor | -0.0182256 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.01821 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0181776 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0181482 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0181171 |
| MECOM | MDS1 and EVI1 complex locus | -0.0177169 |
| RPS13 | ribosomal protein S13 | -0.0177143 |
| FBXO11 | F-box protein 11 | -0.017483 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0173684 |
| APOL6 | apolipoprotein L, 6 | -0.0172974 |
| HLA-B | major histocompatibility complex, class I, B | -0.0172026 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0170872 |
| ACTG1 | actin gamma 1 | -0.0168722 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0165687 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0165569 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0165297 |
| CREBBP | CREB binding protein | -0.016391 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0159952 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.015802 |
| RPL35 | ribosomal protein L35 | -0.0157499 |
| LAMC2 | laminin, gamma 2 | -0.0157425 |
| CAVIN1 | caveolae associated protein 1 | -0.0156974 |
| C4BPB | complement component 4 binding protein, beta | -0.0156415 |
| CDK6 | cyclin-dependent kinase 6 | -0.0153948 |
| TJP1 | tight junction protein 1 | -0.0153741 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.015331 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0153281 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0153199 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0152762 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0151419 |
| PMP22 | peripheral myelin protein 22 | -0.0150304 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0150225 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0149657 |
| NUMB | numb homolog (Drosophila) | -0.0148593 |
| DGKH | diacylglycerol kinase, eta | -0.0146144 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 | -0.0144458 |
| NRG1 | neuregulin 1 | -0.0144449 |
| EFNA5 | ephrin-A5 | -0.0143935 |
