| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.177143 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.112979 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0883769 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0842556 |
| PTMA | prothymosin, alpha | 0.0839307 |
| ZNF292 | zinc finger protein 292 | 0.0714212 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0694442 |
| TMSB4X | thymosin beta 4, X-linked | 0.0685216 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0658826 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0642498 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0632196 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0631683 |
| HDAC9 | histone deacetylase 9 | 0.0610968 |
| ATXN1 | ataxin 1 | 0.0601703 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0592157 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0585083 |
| GOLGA4 | golgin A4 | 0.0570691 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0568765 |
| CCNY | cyclin Y | 0.0544161 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0530375 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0522884 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0516999 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0506568 |
| FNIP1 | folliculin interacting protein 1 | 0.0505775 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0504029 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0500501 |
| MED13L | mediator complex subunit 13-like | 0.0499103 |
| RPS12 | ribosomal protein S12 | 0.0489701 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0485846 |
| TSC22D2 | TSC22 domain family, member 2 | 0.047942 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0477619 |
| JMJD1C | jumonji domain containing 1C | 0.0460744 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0457558 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0451195 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0439159 |
| FRMD5 | FERM domain containing 5 | 0.0436535 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0434458 |
| ENO1 | enolase 1, (alpha) | 0.0433344 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0432298 |
| FAM13A | family with sequence similarity 13, member A | 0.0431694 |
| SIK3 | SIK family kinase 3 | 0.0423331 |
| DST | dystonin | 0.0420026 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0413326 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0407116 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0406764 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.039752 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0397345 |
| FOXO3 | forkhead box O3 | 0.0394256 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.038666 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0384954 |
| SMAD3 | SMAD family member 3 | 0.038175 |
| PGK1 | phosphoglycerate kinase 1 | 0.0381707 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0380635 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0379374 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0377833 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0376114 |
| NFIB | nuclear factor I/B | 0.0373782 |
| SQSTM1 | sequestosome 1 | 0.0367738 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0367249 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0362269 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0360163 |
| VEGFA | vascular endothelial growth factor A | 0.0354519 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0353687 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0349197 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0349059 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0348372 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0341981 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0340662 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0340376 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0333797 |
| SNX13 | sorting nexin 13 | 0.033259 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332396 |
| KLHL29 | kelch-like family member 29 | 0.0330981 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0325855 |
| SLMAP | sarcolemma associated protein | 0.032286 |
| EZR | ezrin | 0.0322586 |
| PTK2 | protein tyrosine kinase 2 | 0.0322343 |
| ANLN | anillin, actin binding protein | 0.0322204 |
| HMGB2 | high mobility group box 2 | 0.0320962 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0315452 |
| RPS3 | ribosomal protein S3 | 0.031327 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0312004 |
| AFDN | afadin, adherens junction formation factor | 0.0309995 |
| COG5 | component of oligomeric golgi complex 5 | 0.0300911 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0295305 |
| MECOM | MDS1 and EVI1 complex locus | 0.0295069 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0291515 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0290534 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0290281 |
| RSF1 | remodeling and spacing factor 1 | 0.0287659 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0286082 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0284974 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0283822 |
| NPSR1 | neuropeptide S receptor 1 | 0.0282597 |
| RNF145 | ring finger protein 145 | 0.0281076 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0279576 |
| TES | testin LIM domain protein | 0.0278478 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0277087 |
| STK24 | serine/threonine kinase 24 | 0.0276574 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0275732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166513 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0970512 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0895108 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0821186 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0807891 |
| AGR2 | anterior gradient 2 | -0.0577122 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.057429 |
| RRBP1 | ribosome binding protein 1 | -0.0563661 |
| S100A10 | S100 calcium binding protein A10 | -0.0541959 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0524262 |
| TMC5 | transmembrane channel-like 5 | -0.0519649 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0466841 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.044437 |
| EMP1 | epithelial membrane protein 1 | -0.0439862 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0402832 |
| HLA-A | major histocompatibility complex, class I, A | -0.0402385 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0402121 |
| RNF213 | ring finger protein 213 | -0.0386371 |
| GPX2 | glutathione peroxidase 2 | -0.0379211 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0374585 |
| TMEM123 | transmembrane protein 123 | -0.0358843 |
| PKM | pyruvate kinase, muscle | -0.0329619 |
| MUC17 | mucin 17, cell surface associated | -0.0327303 |
| HLA-E | major histocompatibility complex, class I, E | -0.0325431 |
| LMO7 | LIM domain 7 | -0.0318589 |
| MUC1 | mucin 1, cell surface associated | -0.0311037 |
| ANXA2 | annexin A2 | -0.0309994 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0307791 |
| FTL | ferritin, light polypeptide | -0.0304284 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0297707 |
| ACTN4 | actinin, alpha 4 | -0.0296965 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0285954 |
| ATF5 | activating transcription factor 5 | -0.0285321 |
| CLDN7 | claudin 7 | -0.0283244 |
| RPL35A | ribosomal protein L35a | -0.0279996 |
| HLA-C | major histocompatibility complex, class I, C | -0.0273691 |
| ITGA6 | integrin, alpha 6 | -0.0273646 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0269687 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0266888 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0266549 |
| FASN | fatty acid synthase | -0.0263627 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0263523 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0261924 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0260644 |
| INSIG1 | insulin induced gene 1 | -0.0258283 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0257278 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0255656 |
| EPCAM | epithelial cell adhesion molecule | -0.02528 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0252661 |
| RPL8 | ribosomal protein L8 | -0.0249653 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0245758 |
| ASTN2 | astrotactin 2 | -0.0242519 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0241922 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0240755 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0239026 |
| ACTG1 | actin gamma 1 | -0.0238316 |
| XAF1 | XIAP associated factor 1 | -0.0236847 |
| PLSCR1 | phospholipid scramblase 1 | -0.023308 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0232322 |
| RPL23 | ribosomal protein L23 | -0.0226456 |
| HMGA1 | high mobility group AT-hook 1 | -0.0226338 |
| MUC13 | mucin 13, cell surface associated | -0.022417 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0221115 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0220221 |
| HLA-B | major histocompatibility complex, class I, B | -0.0215548 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0215509 |
| SLC38A2 | solute carrier family 38, member 2 | -0.021493 |
| LYZ | lysozyme | -0.0212686 |
| FAT1 | FAT atypical cadherin 1 | -0.0212429 |
| TFF2 | trefoil factor 2 | -0.0212205 |
| H1-0 | H1.0 linker histone | -0.0211618 |
| LAMA4 | laminin, alpha 4 | -0.0211194 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0211113 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0207373 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0206013 |
| BPTF | bromodomain PHD finger transcription factor | -0.0205548 |
| SULF2 | sulfatase 2 | -0.0204009 |
| POTEF | POTE ankyrin domain family, member F | -0.0203577 |
| RIGI | RNA sensor RIG-I | -0.0203073 |
| SEPTIN9 | septin 9 | -0.0202063 |
| S100A11 | S100 calcium binding protein A11 | -0.0199242 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.019872 |
| RPL28 | ribosomal protein L28 | -0.019604 |
| KLK10 | kallikrein-related peptidase 10 | -0.019584 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0195227 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.019202 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0189446 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0188913 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0188802 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0188172 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0187498 |
| TMSB10 | thymosin beta 10 | -0.018733 |
| ATM | ATM serine/threonine kinase | -0.0186903 |
| DEK | DEK proto-oncogene | -0.0185733 |
| AHNAK | AHNAK nucleoprotein | -0.0181933 |
| TMEM45B | transmembrane protein 45B | -0.0181281 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0180563 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.018037 |
| CALR | calreticulin | -0.0179724 |
| WDR45B | WD repeat domain 45B | -0.0179213 |
