| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Penfluridol_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.122249 |
| PM20D1 | peptidase M20 domain containing 1 | 0.118282 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.101695 |
| TXNRD1 | thioredoxin reductase 1 | 0.0952119 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.053769 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.045294 |
| ASPH | aspartate beta-hydroxylase | 0.0365192 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0362666 |
| WWOX | WW domain containing oxidoreductase | 0.0340988 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0318202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0313967 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0312752 |
| HSPA8 | heat shock 70kDa protein 8 | 0.031121 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0308999 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0283827 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0265571 |
| AHR | aryl hydrocarbon receptor | 0.0261597 |
| BICC1 | BicC family RNA binding protein 1 | 0.0255379 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0253453 |
| HDAC9 | histone deacetylase 9 | 0.0238011 |
| RPL4 | ribosomal protein L4 | 0.0234668 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0231092 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0228438 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0222912 |
| CENPF | centromere protein F, 350/400kDa | 0.0217098 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0215165 |
| ECT2 | epithelial cell transforming 2 | 0.021516 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.02105 |
| EFNA5 | ephrin-A5 | 0.0205357 |
| FGB | fibrinogen beta chain | 0.0204197 |
| RTN4 | reticulon 4 | 0.0200037 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0198719 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0192234 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0191007 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0190806 |
| TBC1D5 | TBC1 domain family, member 5 | 0.018182 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0179563 |
| RRM2 | ribonucleotide reductase M2 | 0.0179511 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0177626 |
| MKI67 | marker of proliferation Ki-67 | 0.0174785 |
| CANX | calnexin | 0.0171368 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0169866 |
| RAD51B | RAD51 paralog B | 0.0166511 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0166249 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0160494 |
| TNPO1 | transportin 1 | 0.0159055 |
| WDR43 | WD repeat domain 43 | 0.0156236 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0152148 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0146878 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.014245 |
| FGG | fibrinogen gamma chain | 0.0141769 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0141326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0137822 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0136081 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.013441 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0134244 |
| ANLN | anillin, actin binding protein | 0.0133649 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0133034 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0131904 |
| HMGB2 | high mobility group box 2 | 0.013186 |
| GLIS3 | GLIS family zinc finger 3 | 0.0131594 |
| AATF | apoptosis antagonizing transcription factor | 0.0130641 |
| RPL7 | ribosomal protein L7 | 0.0130242 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0129574 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0129507 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0128701 |
| TPX2 | TPX2, microtubule-associated | 0.0127525 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.012474 |
| SPIDR | scaffolding protein involved in DNA repair | 0.012442 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0124289 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0123966 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0123063 |
| PTMA | prothymosin, alpha | 0.0122749 |
| MEMO1 | mediator of cell motility 1 | 0.0122268 |
| TPM3 | tropomyosin 3 | 0.0121649 |
| SP3 | Sp3 transcription factor | 0.0121427 |
| NTN4 | netrin 4 | 0.0120989 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0120444 |
| APP | amyloid beta (A4) precursor protein | 0.0120122 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0118878 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0118786 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0117365 |
| RPS12 | ribosomal protein S12 | 0.0116628 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0116505 |
| RPS7 | ribosomal protein S7 | 0.0116292 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0115271 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.011403 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0113539 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0111218 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.011101 |
| DST | dystonin | 0.0110993 |
| ENAH | enabled homolog (Drosophila) | 0.0110975 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0110963 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0109957 |
| RPL3 | ribosomal protein L3 | 0.0109855 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0109839 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0109706 |
| CMC2 | C-x(9)-C motif containing 2 | 0.0109495 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0107519 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.010704 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.286741 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.20396 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.158157 |
| VIM | vimentin | -0.12474 |
| IGF2 | insulin-like growth factor 2 | -0.0994948 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0971126 |
| TMSB10 | thymosin beta 10 | -0.0731235 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0635487 |
| ACTG1 | actin gamma 1 | -0.0624207 |
| FTL | ferritin, light polypeptide | -0.056967 |
| PYGL | phosphorylase, glycogen, liver | -0.0545294 |
| POTEF | POTE ankyrin domain family, member F | -0.0539132 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0519173 |
| HLA-B | major histocompatibility complex, class I, B | -0.0512961 |
| FLNB | filamin B, beta | -0.0460359 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0455403 |
| S100A6 | S100 calcium binding protein A6 | -0.0455294 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.042891 |
| FMNL2 | formin-like 2 | -0.0414513 |
| IER3 | immediate early response 3 | -0.0390418 |
| NDRG1 | N-myc downstream regulated 1 | -0.0384585 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.037922 |
| CMIP | c-Maf inducing protein | -0.0364558 |
| RBM25 | RNA binding motif protein 25 | -0.0363608 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0359424 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0357708 |
| HLA-A | major histocompatibility complex, class I, A | -0.0356082 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0343102 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0334615 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0329303 |
| IL6 | interleukin 6 | -0.0326654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0313088 |
| PKM | pyruvate kinase, muscle | -0.0297597 |
| EGFR | epidermal growth factor receptor | -0.0297172 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0295331 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0293012 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0292608 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283874 |
| RAB7A | RAB7A, member RAS oncogene family | -0.028382 |
| COPA | coatomer protein complex, subunit alpha | -0.0278296 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0276384 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0273613 |
| ZNF207 | zinc finger protein 207 | -0.0273548 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0273281 |
| S100A10 | S100 calcium binding protein A10 | -0.0264473 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0263224 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.026074 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.025943 |
| RPS8 | ribosomal protein S8 | -0.0258352 |
| RPL35A | ribosomal protein L35a | -0.0256222 |
| GLG1 | golgi glycoprotein 1 | -0.0255969 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0254636 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0246702 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0245953 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0242636 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0235903 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0231992 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0230836 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0229325 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0228801 |
| NOP58 | NOP58 ribonucleoprotein | -0.0228137 |
| PFN1 | profilin 1 | -0.0221181 |
| EGR1 | early growth response 1 | -0.0220957 |
| MYO1E | myosin IE | -0.0219253 |
| ACTN1 | actinin, alpha 1 | -0.0218964 |
| RPLP1 | ribosomal protein, large, P1 | -0.0218805 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0218253 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0217232 |
| LDHA | lactate dehydrogenase A | -0.0215299 |
| RBM39 | RNA binding motif protein 39 | -0.0214773 |
| CD99 | CD99 molecule | -0.0214197 |
| RPS6 | ribosomal protein S6 | -0.0208531 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0207042 |
| MT1X | metallothionein 1X | -0.0205732 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.020504 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0204562 |
| PARD3 | par-3 family cell polarity regulator | -0.0204215 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0203462 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0202372 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.020209 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0199874 |
| RPL31 | ribosomal protein L31 | -0.019547 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0194231 |
| USP36 | ubiquitin specific peptidase 36 | -0.0191627 |
| RPL23 | ribosomal protein L23 | -0.0190947 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0186167 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0185639 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.018524 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.018481 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0184228 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0182835 |
| TPM4 | tropomyosin 4 | -0.0181625 |
| SRP54 | signal recognition particle 54kDa | -0.0181385 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0180877 |
| HMGA1 | high mobility group AT-hook 1 | -0.0179767 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0178495 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0177715 |
| GOLGA4 | golgin A4 | -0.0177506 |
| HM13 | histocompatibility (minor) 13 | -0.0176183 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0175373 |
