| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Penfluridol_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMNL2 | formin-like 2 | 0.0678042 |
| GPC6 | glypican 6 | 0.0652238 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0626316 |
| NDRG1 | N-myc downstream regulated 1 | 0.0599826 |
| APP | amyloid beta (A4) precursor protein | 0.0584688 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.057827 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0577586 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0574701 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0561147 |
| JMJD1C | jumonji domain containing 1C | 0.0542553 |
| TPR | translocated promoter region, nuclear basket protein | 0.0528987 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0522654 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0519948 |
| KYNU | kynureninase | 0.0510212 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.049981 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0485746 |
| RNF145 | ring finger protein 145 | 0.0481272 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0475029 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0473707 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0454418 |
| GRB10 | growth factor receptor-bound protein 10 | 0.045334 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0445472 |
| LAMB3 | laminin, beta 3 | 0.043979 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0437533 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0436939 |
| RUNX1 | runt-related transcription factor 1 | 0.0428587 |
| PDE10A | phosphodiesterase 10A | 0.0428057 |
| UTRN | utrophin | 0.0425866 |
| SRPK2 | SRSF protein kinase 2 | 0.0422794 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0419126 |
| GOLGA4 | golgin A4 | 0.0414515 |
| GLG1 | golgi glycoprotein 1 | 0.0410897 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.040212 |
| USP34 | ubiquitin specific peptidase 34 | 0.0397934 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0396709 |
| SPAG9 | sperm associated antigen 9 | 0.0391549 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0387649 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0387228 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387028 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0383835 |
| GDNF | glial cell derived neurotrophic factor | 0.0382454 |
| USP15 | ubiquitin specific peptidase 15 | 0.0381286 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0377353 |
| CANX | calnexin | 0.0375148 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0371739 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0368673 |
| COG5 | component of oligomeric golgi complex 5 | 0.0362722 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0360702 |
| RPS16 | ribosomal protein S16 | 0.0360126 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.03585 |
| RTN4 | reticulon 4 | 0.0355419 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0352787 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0349575 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0345952 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0344336 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0343285 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0341059 |
| DIAPH1 | diaphanous-related formin 1 | 0.033707 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0335377 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0334831 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.033081 |
| FNIP1 | folliculin interacting protein 1 | 0.0328721 |
| MATR3 | matrin 3 | 0.0324035 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0320309 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0320202 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0314951 |
| FRYL | FRY-like | 0.0313552 |
| CCNL1 | cyclin L1 | 0.0312876 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0311684 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0307052 |
| NEMF | nuclear export mediator factor | 0.030588 |
| TMSB4X | thymosin beta 4, X-linked | 0.0305771 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0305438 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0304298 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0303046 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0302448 |
| NBEAL1 | neurobeachin-like 1 | 0.0299655 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0299146 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0296572 |
| PTEN | phosphatase and tensin homolog | 0.0296417 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.029446 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0294459 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0294337 |
| TPD52 | tumor protein D52 | 0.0292755 |
| JAK2 | Janus kinase 2 | 0.0291027 |
| ANXA1 | annexin A1 | 0.0290497 |
| PDLIM5 | PDZ and LIM domain 5 | 0.028986 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0288636 |
| LDLR | low density lipoprotein receptor | 0.0287665 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0286756 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0286279 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0285497 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0283524 |
| CDC73 | cell division cycle 73 | 0.0283523 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0283374 |
| EZR | ezrin | 0.0279934 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0279265 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.027626 |
| CERS6 | ceramide synthase 6 | 0.0276174 |
| RPLP0 | ribosomal protein, large, P0 | 0.0275375 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.123094 |
| VIM | vimentin | -0.105988 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0982339 |
| FN1 | fibronectin 1 | -0.085132 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0831765 |
| HLA-B | major histocompatibility complex, class I, B | -0.0822594 |
| MMP1 | matrix metallopeptidase 1 | -0.0735827 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0723742 |
| RPL19 | ribosomal protein L19 | -0.0691198 |
| RPS8 | ribosomal protein S8 | -0.0683893 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0663383 |
| PGK1 | phosphoglycerate kinase 1 | -0.0659363 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0643165 |
| IGF2 | insulin-like growth factor 2 | -0.0625673 |
| MUC13 | mucin 13, cell surface associated | -0.0602249 |
| PTMA | prothymosin, alpha | -0.0590671 |
| MED13L | mediator complex subunit 13-like | -0.0587023 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0582255 |
| BPTF | bromodomain PHD finger transcription factor | -0.057954 |
| NAV2 | neuron navigator 2 | -0.0578792 |
| NUP98 | nucleoporin 98kDa | -0.0569951 |
| WASF2 | WAS protein family, member 2 | -0.0564942 |
| FTL | ferritin, light polypeptide | -0.0550662 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0542982 |
| EGFR | epidermal growth factor receptor | -0.0537441 |
| MSI2 | musashi RNA-binding protein 2 | -0.0522361 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0500324 |
| TMSB10 | thymosin beta 10 | -0.0491298 |
| INTS6 | integrator complex subunit 6 | -0.0468078 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0458971 |
| RPL7A | ribosomal protein L7a | -0.0449025 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0448036 |
| IER3 | immediate early response 3 | -0.0442927 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0441998 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0436081 |
| METTL15 | methyltransferase like 15 | -0.0435607 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0431759 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0423833 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0418737 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.041748 |
| LDHA | lactate dehydrogenase A | -0.0416734 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0416668 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0415856 |
| RPS11 | ribosomal protein S11 | -0.0411328 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0409978 |
| EXOC2 | exocyst complex component 2 | -0.0405986 |
| RPL15 | ribosomal protein L15 | -0.0392152 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0391168 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0389944 |
| ZNF638 | zinc finger protein 638 | -0.0383357 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0380286 |
| DENND1A | DENN/MADD domain containing 1A | -0.0379568 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.037478 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0374241 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0369477 |
| CSTB | cystatin B (stefin B) | -0.0368668 |
| DNM2 | dynamin 2 | -0.0367765 |
| LASP1 | LIM and SH3 protein 1 | -0.0360464 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.035955 |
| SLC25A51 | solute carrier family 25, member 51 | -0.035671 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0352889 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0349463 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0347618 |
| RPL38 | ribosomal protein L38 | -0.0347311 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0345936 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0342984 |
| RBM15 | RNA binding motif protein 15 | -0.0341886 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0339875 |
| AK1 | adenylate kinase 1 | -0.0339505 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0337792 |
| FAT1 | FAT atypical cadherin 1 | -0.0336427 |
| ASPH | aspartate beta-hydroxylase | -0.0336381 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0336159 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0332748 |
| MUC16 | mucin 16, cell surface associated | -0.0332218 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0329055 |
| AATF | apoptosis antagonizing transcription factor | -0.0327629 |
| HMGB1 | high mobility group box 1 | -0.0327518 |
| RPL35A | ribosomal protein L35a | -0.032701 |
| B2M | beta-2-microglobulin | -0.0326561 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0325761 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0324747 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0321602 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.03214 |
| CD44 | CD44 molecule (Indian blood group) | -0.0315371 |
| ABHD17C | abhydrolase domain containing 17C | -0.0315309 |
| INHBA | inhibin, beta A | -0.0313678 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0313178 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0310825 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0310132 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0309193 |
| GPHN | gephyrin | -0.0307259 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0306415 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0305772 |
| H1-0 | H1.0 linker histone | -0.0303883 |
| GOLGA2 | golgin A2 | -0.0302884 |
| RPS10 | ribosomal protein S10 | -0.0300371 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0298225 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0298175 |
| KIF13B | kinesin family member 13B | -0.0298032 |
