| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.194095 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.179206 |
| EFNA5 | ephrin-A5 | 0.164718 |
| ASPH | aspartate beta-hydroxylase | 0.155578 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.131064 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.106165 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0936769 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0932209 |
| PGK1 | phosphoglycerate kinase 1 | 0.0930833 |
| NRCAM | neuronal cell adhesion molecule | 0.0800955 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0797798 |
| TXNRD1 | thioredoxin reductase 1 | 0.0742265 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0710697 |
| ENO1 | enolase 1, (alpha) | 0.0708954 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0693287 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0683521 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0636736 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0612726 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0599596 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0591647 |
| MYOF | myoferlin | 0.0577315 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0565225 |
| GRAMD1B | GRAM domain containing 1B | 0.055029 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0539826 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0524053 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0516209 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0508006 |
| PTMA | prothymosin, alpha | 0.0506757 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0494784 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0483994 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0482315 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0480284 |
| NEK7 | NIMA-related kinase 7 | 0.0474556 |
| CANX | calnexin | 0.044667 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.042836 |
| FAM13A | family with sequence similarity 13, member A | 0.0421586 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0415031 |
| MSN | moesin | 0.0407918 |
| OGA | O-GlcNAcase | 0.0390538 |
| TMSB4X | thymosin beta 4, X-linked | 0.0388915 |
| ZNF292 | zinc finger protein 292 | 0.0379552 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0375035 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0371637 |
| CENPF | centromere protein F, 350/400kDa | 0.0371071 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0370995 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0368793 |
| RTN4 | reticulon 4 | 0.0366175 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0358837 |
| MATR3 | matrin 3 | 0.0356615 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0353543 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0351759 |
| TNPO1 | transportin 1 | 0.0350596 |
| SPAG9 | sperm associated antigen 9 | 0.034624 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0340474 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0331221 |
| PCBP3 | poly(rC) binding protein 3 | 0.0321943 |
| NCKAP1 | NCK-associated protein 1 | 0.0320758 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320179 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0319127 |
| LDHA | lactate dehydrogenase A | 0.0318549 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0317688 |
| APP | amyloid beta (A4) precursor protein | 0.0314342 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0314052 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0312353 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0309882 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0309128 |
| RPL3 | ribosomal protein L3 | 0.0308346 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0306819 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0303004 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.029638 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0291631 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0290749 |
| NUP58 | nucleoporin 58 | 0.0289167 |
| USP3 | ubiquitin specific peptidase 3 | 0.0289031 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0286818 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0285279 |
| SET | SET nuclear proto-oncogene | 0.0280705 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.028041 |
| RNF145 | ring finger protein 145 | 0.027914 |
| BDNF | brain-derived neurotrophic factor | 0.027772 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0276152 |
| ANXA1 | annexin A1 | 0.0273772 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.027094 |
| FMNL2 | formin-like 2 | 0.0270783 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0270673 |
| XPO1 | exportin 1 | 0.0269766 |
| MKI67 | marker of proliferation Ki-67 | 0.0269341 |
| FLNB | filamin B, beta | 0.0265555 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0265219 |
| NBAS | neuroblastoma amplified sequence | 0.0264844 |
| PCBP2 | poly(rC) binding protein 2 | 0.0264802 |
| ANXA5 | annexin A5 | 0.0264666 |
| CDC73 | cell division cycle 73 | 0.0262959 |
| DNER | delta/notch-like EGF repeat containing | 0.0260865 |
| TPM3 | tropomyosin 3 | 0.0258406 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0258009 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0256719 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0255867 |
| MCL1 | myeloid cell leukemia 1 | 0.025475 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0254125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.290432 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112151 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0710126 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0683265 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0624457 |
| VIM | vimentin | -0.0590626 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.057583 |
| FN1 | fibronectin 1 | -0.0506071 |
| TMSB10 | thymosin beta 10 | -0.0487964 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0452784 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0412579 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0403912 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0395848 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0374574 |
| RPLP1 | ribosomal protein, large, P1 | -0.0355421 |
| DOCK5 | dedicator of cytokinesis 5 | -0.033981 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0338567 |
| RPL35A | ribosomal protein L35a | -0.0330363 |
| HLA-A | major histocompatibility complex, class I, A | -0.0330258 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0327169 |
| FTL | ferritin, light polypeptide | -0.0319411 |
| EGR1 | early growth response 1 | -0.0319197 |
| LAMA5 | laminin, alpha 5 | -0.0311807 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0310464 |
| RPS6 | ribosomal protein S6 | -0.0309057 |
| RTN1 | reticulon 1 | -0.0290046 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0278028 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0277842 |
| HLA-B | major histocompatibility complex, class I, B | -0.0272179 |
| RPS19 | ribosomal protein S19 | -0.0271128 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0261531 |
| RPS8 | ribosomal protein S8 | -0.024745 |
| RPL34 | ribosomal protein L34 | -0.0243723 |
| VCL | vinculin | -0.0242984 |
| NTN4 | netrin 4 | -0.0232922 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0225576 |
| RPL31 | ribosomal protein L31 | -0.022537 |
| ASTN2 | astrotactin 2 | -0.0224726 |
| RPS27 | ribosomal protein S27 | -0.0222871 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0214145 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0213638 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0211996 |
| DST | dystonin | -0.0206522 |
| RPS29 | ribosomal protein S29 | -0.0204742 |
| GDA | guanine deaminase | -0.02041 |
| SMAD2 | SMAD family member 2 | -0.0203864 |
| RPS13 | ribosomal protein S13 | -0.0197896 |
| OSMR | oncostatin M receptor | -0.0196688 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0195238 |
| IL6 | interleukin 6 | -0.0193849 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0189921 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0187531 |
| EPHA4 | EPH receptor A4 | -0.0187168 |
| FOXK1 | forkhead box K1 | -0.0184319 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0184187 |
| CHL1 | cell adhesion molecule L1-like | -0.0184023 |
| MT2A | metallothionein 2A | -0.0183586 |
| CUX1 | cut-like homeobox 1 | -0.0183055 |
| TBCA | tubulin folding cofactor A | -0.0183038 |
| RPL37A | ribosomal protein L37a | -0.0179011 |
| BPTF | bromodomain PHD finger transcription factor | -0.0178838 |
| PDE10A | phosphodiesterase 10A | -0.0169854 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0168457 |
| EXT1 | exostosin glycosyltransferase 1 | -0.016593 |
| RAB31 | RAB31, member RAS oncogene family | -0.0162081 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0161982 |
| COL5A2 | collagen, type V, alpha 2 | -0.0160991 |
| NABP1 | nucleic acid binding protein 1 | -0.0160381 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0158969 |
| HDAC4 | histone deacetylase 4 | -0.0157835 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0155749 |
| RPL9 | ribosomal protein L9 | -0.0153515 |
| RPLP2 | ribosomal protein, large, P2 | -0.0151726 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0151604 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0150876 |
| RPL36 | ribosomal protein L36 | -0.0149102 |
| RPS11 | ribosomal protein S11 | -0.0149036 |
| RPL12 | ribosomal protein L12 | -0.0148169 |
| RPS23 | ribosomal protein S23 | -0.0147287 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0147138 |
| PCNX4 | pecanex 4 | -0.0146595 |
| RPL26 | ribosomal protein L26 | -0.014615 |
| KIAA0825 | KIAA0825 | -0.0145614 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0145316 |
| LAMB1 | laminin, beta 1 | -0.0144822 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0143847 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0143829 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0143677 |
| TMEM144 | transmembrane protein 144 | -0.0143112 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0142554 |
| ITGB8 | integrin, beta 8 | -0.014249 |
| RPL28 | ribosomal protein L28 | -0.0142268 |
| INTS6 | integrator complex subunit 6 | -0.0141813 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0137038 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0134366 |
| CREM | cAMP responsive element modulator | -0.0133565 |
| RANBP17 | RAN binding protein 17 | -0.0133505 |
| LSAMP | limbic system-associated membrane protein | -0.0132704 |
| GNAS | GNAS complex locus | -0.0129972 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0129066 |
