| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.218415 |
| COL11A1 | collagen, type XI, alpha 1 | 0.190773 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.179406 |
| TMSB4X | thymosin beta 4, X-linked | 0.126547 |
| COL5A2 | collagen, type V, alpha 2 | 0.123471 |
| PTMA | prothymosin, alpha | 0.103937 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.091106 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0893639 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0874951 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0742312 |
| CALR | calreticulin | 0.0725828 |
| RPS12 | ribosomal protein S12 | 0.071657 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0700654 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.069916 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0658105 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0647326 |
| DST | dystonin | 0.0643046 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0618248 |
| PCDH9 | protocadherin 9 | 0.0608204 |
| TENM3 | teneurin transmembrane protein 3 | 0.060199 |
| CADM2 | cell adhesion molecule 2 | 0.0597215 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0595277 |
| COL3A1 | collagen, type III, alpha 1 | 0.05761 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0546162 |
| H1-0 | H1.0 linker histone | 0.0539232 |
| PLPP1 | phospholipid phosphatase 1 | 0.0535889 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0526184 |
| PGK1 | phosphoglycerate kinase 1 | 0.0511892 |
| RAD51B | RAD51 paralog B | 0.0510301 |
| LRRC4C | leucine rich repeat containing 4C | 0.0501642 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0484853 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0482851 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0476425 |
| RPS6 | ribosomal protein S6 | 0.0471286 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0464494 |
| CENPF | centromere protein F, 350/400kDa | 0.046394 |
| ENO1 | enolase 1, (alpha) | 0.0440328 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0439299 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0430067 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0422752 |
| SLK | STE20-like kinase | 0.0421362 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0421148 |
| YAP1 | Yes-associated protein 1 | 0.0410706 |
| PCDH7 | protocadherin 7 | 0.0406064 |
| AHNAK | AHNAK nucleoprotein | 0.040509 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0404076 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0401801 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0393447 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0393012 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.039026 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0388357 |
| MKI67 | marker of proliferation Ki-67 | 0.0383035 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0381822 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0378135 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0376274 |
| RPL31 | ribosomal protein L31 | 0.0370194 |
| CANX | calnexin | 0.0367452 |
| RPL11 | ribosomal protein L11 | 0.0359839 |
| CORO1C | coronin, actin binding protein, 1C | 0.0356932 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.035651 |
| PDGFC | platelet derived growth factor C | 0.0345768 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0344564 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0340711 |
| FN1 | fibronectin 1 | 0.0340276 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.033788 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0337456 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.03344 |
| LDHA | lactate dehydrogenase A | 0.0333122 |
| QKI | QKI, KH domain containing, RNA binding | 0.0327748 |
| APP | amyloid beta (A4) precursor protein | 0.0324556 |
| RPLP0 | ribosomal protein, large, P0 | 0.0323864 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0323001 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0319175 |
| PRELID2 | PRELI domain containing 2 | 0.0316426 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0312374 |
| SETD5 | SET domain containing 5 | 0.031208 |
| MORF4L2 | mortality factor 4 like 2 | 0.0312044 |
| CCN2 | cellular communication network factor 2 | 0.0311235 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0308197 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.030759 |
| EP300 | E1A binding protein p300 | 0.030655 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0306051 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0305371 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0300126 |
| B2M | beta-2-microglobulin | 0.0297897 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0297891 |
| TENM2 | teneurin transmembrane protein 2 | 0.0296238 |
| RPL3 | ribosomal protein L3 | 0.0295012 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.029332 |
| RAB14 | RAB14, member RAS oncogene family | 0.0292965 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0290494 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0288466 |
| PROS1 | protein S (alpha) | 0.0286077 |
| POSTN | periostin, osteoblast specific factor | 0.0284857 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0284721 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0281418 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0279147 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0278361 |
| CFL2 | cofilin 2 (muscle) | 0.0277594 |
| SET | SET nuclear proto-oncogene | 0.0276634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0883319 |
| MAP4 | microtubule-associated protein 4 | -0.0551302 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0536345 |
| SPAG9 | sperm associated antigen 9 | -0.0527063 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0522883 |
| GPC3 | glypican 3 | -0.0489355 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0459019 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0448416 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0417626 |
| PEG10 | paternally expressed 10 | -0.0408502 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0405442 |
| PARD3 | par-3 family cell polarity regulator | -0.038739 |
| WDR43 | WD repeat domain 43 | -0.0384509 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0370601 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.035848 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0338033 |
| NUP58 | nucleoporin 58 | -0.0326864 |
| CDH19 | cadherin 19, type 2 | -0.0316966 |
| TMSB10 | thymosin beta 10 | -0.0316018 |
| TFRC | transferrin receptor | -0.0308059 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0303566 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0303416 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0301302 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0299157 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0293515 |
| ACTG1 | actin gamma 1 | -0.0276533 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0275865 |
| ACTN4 | actinin, alpha 4 | -0.0271924 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0269713 |
| ANXA2 | annexin A2 | -0.0265788 |
| PALLD | palladin, cytoskeletal associated protein | -0.0263721 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.02604 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0259882 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0258467 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0257843 |
| EVI5 | ecotropic viral integration site 5 | -0.0249277 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0249034 |
| AK1 | adenylate kinase 1 | -0.0247659 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0246755 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0239652 |
| SEPTIN7 | septin 7 | -0.0236204 |
| ABI1 | abl-interactor 1 | -0.023372 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0229897 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0229794 |
| COG5 | component of oligomeric golgi complex 5 | -0.0227755 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.022727 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0227145 |
| RTN4 | reticulon 4 | -0.0225706 |
| ZFR | zinc finger RNA binding protein | -0.0220129 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0219822 |
| RDX | radixin | -0.0219703 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0219567 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0219567 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0218869 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0217254 |
| USP3 | ubiquitin specific peptidase 3 | -0.0217221 |
| CAPNS1 | calpain, small subunit 1 | -0.0217164 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0215816 |
| SIK2 | salt-inducible kinase 2 | -0.0213915 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0212567 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0211279 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0211174 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0210009 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0209506 |
| USP15 | ubiquitin specific peptidase 15 | -0.020888 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0208127 |
| LATS2 | large tumor suppressor kinase 2 | -0.0206848 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0202783 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0201234 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.0201026 |
| NPR2 | natriuretic peptide receptor 2 | -0.0200821 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0199933 |
| PTEN | phosphatase and tensin homolog | -0.0199139 |
| RPL5 | ribosomal protein L5 | -0.0198975 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0197416 |
| YLPM1 | YLP motif containing 1 | -0.0196887 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0196429 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0196188 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0196134 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | -0.019598 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0195528 |
| SYT1 | synaptotagmin I | -0.0195229 |
| NBEAL1 | neurobeachin-like 1 | -0.019441 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0193469 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | -0.019325 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.019228 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0191439 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0190101 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.018814 |
| FOXK2 | forkhead box K2 | -0.0187808 |
| S100A10 | S100 calcium binding protein A10 | -0.0187344 |
| WBP11 | WW domain binding protein 11 | -0.0187022 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.01867 |
| TPM1 | tropomyosin 1 (alpha) | -0.0184882 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0183617 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.0183198 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | -0.0182245 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0181718 |
| TBCB | tubulin folding cofactor B | -0.0181465 |
| INO80 | INO80 complex subunit | -0.01812 |
