| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.183887 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.149769 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.141813 |
| FNDC3B | fibronectin type III domain containing 3B | 0.129447 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.105859 |
| NAV2 | neuron navigator 2 | 0.0737134 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0717625 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0671101 |
| RTN4 | reticulon 4 | 0.0623757 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0620669 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0606108 |
| MKI67 | marker of proliferation Ki-67 | 0.0590322 |
| MSN | moesin | 0.059016 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0579761 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.056186 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.050531 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0496671 |
| TXNRD1 | thioredoxin reductase 1 | 0.0494674 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0484154 |
| CENPF | centromere protein F, 350/400kDa | 0.0469432 |
| ARRDC3 | arrestin domain containing 3 | 0.0460592 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0438768 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0404005 |
| ZNF292 | zinc finger protein 292 | 0.039862 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0398612 |
| ANLN | anillin, actin binding protein | 0.0393243 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0386806 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0373176 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0372249 |
| CCNL1 | cyclin L1 | 0.0368863 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0362603 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0348563 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0342085 |
| SPAG9 | sperm associated antigen 9 | 0.0335501 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0330461 |
| AFDN | afadin, adherens junction formation factor | 0.0315061 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.031356 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0312805 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.029687 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0296701 |
| EZR | ezrin | 0.0294957 |
| KIF4A | kinesin family member 4A | 0.0291358 |
| SMAD3 | SMAD family member 3 | 0.0290573 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0289791 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0289274 |
| JMJD1C | jumonji domain containing 1C | 0.0286018 |
| RNF145 | ring finger protein 145 | 0.028389 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.028234 |
| OGA | O-GlcNAcase | 0.0279573 |
| FRMD4A | FERM domain containing 4A | 0.0279477 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0278578 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0276127 |
| PTMA | prothymosin, alpha | 0.0276058 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0264897 |
| SBF2 | SET binding factor 2 | 0.0259978 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0253815 |
| MX1 | MX dynamin-like GTPase 1 | 0.0253018 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0251286 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0247907 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0245877 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0242515 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0239968 |
| PLPP6 | phospholipid phosphatase 6 | 0.0238138 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0230522 |
| QKI | QKI, KH domain containing, RNA binding | 0.0229962 |
| XPO1 | exportin 1 | 0.0228891 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0224439 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0223345 |
| B2M | beta-2-microglobulin | 0.0223289 |
| SYAP1 | synapse associated protein 1 | 0.0222793 |
| DUSP5 | dual specificity phosphatase 5 | 0.0222356 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0221853 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.021956 |
| PCBP2 | poly(rC) binding protein 2 | 0.021921 |
| KIF11 | kinesin family member 11 | 0.0218987 |
| ARF4 | ADP-ribosylation factor 4 | 0.0218324 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.021789 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0217772 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0217769 |
| MATR3 | matrin 3 | 0.0217132 |
| NEK7 | NIMA-related kinase 7 | 0.0213638 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0213485 |
| TPX2 | TPX2, microtubule-associated | 0.0210224 |
| TGFB2 | transforming growth factor, beta 2 | 0.0210093 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0209831 |
| LMO7 | LIM domain 7 | 0.0207157 |
| CEP250 | centrosomal protein 250kDa | 0.0205336 |
| PDE10A | phosphodiesterase 10A | 0.0202081 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0201794 |
| YBX3 | Y box binding protein 3 | 0.0200533 |
| KLF6 | Kruppel-like factor 6 | 0.0199784 |
| NUP153 | nucleoporin 153kDa | 0.0197074 |
| FLNA | filamin A, alpha | 0.0196975 |
| ANXA5 | annexin A5 | 0.0196539 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0196292 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0195293 |
| RBM39 | RNA binding motif protein 39 | 0.0195286 |
| MYOF | myoferlin | 0.0192769 |
| WWC1 | WW and C2 domain containing 1 | 0.0192706 |
| DENND5A | DENN/MADD domain containing 5A | 0.0189532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.184599 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.145526 |
| HMGA2 | high mobility group AT-hook 2 | -0.134357 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.132593 |
| GLIS3 | GLIS family zinc finger 3 | -0.123758 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104627 |
| CDH13 | cadherin 13 | -0.101314 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0890638 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0852119 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0841406 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0810203 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0772391 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0762623 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0724991 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0719982 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0714534 |
| INTS6 | integrator complex subunit 6 | -0.0596897 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0594982 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0583692 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0574918 |
| HLA-B | major histocompatibility complex, class I, B | -0.0551657 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0537881 |
| COL5A1 | collagen, type V, alpha 1 | -0.0527845 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0501511 |
| TMSB10 | thymosin beta 10 | -0.0490991 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0487895 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0475892 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0471017 |
| AHNAK | AHNAK nucleoprotein | -0.0468501 |
| FTL | ferritin, light polypeptide | -0.0463053 |
| HDAC9 | histone deacetylase 9 | -0.0456246 |
| EFNA5 | ephrin-A5 | -0.0452855 |
| LDHA | lactate dehydrogenase A | -0.0452206 |
| LOX | lysyl oxidase | -0.0441623 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0438622 |
| HLA-A | major histocompatibility complex, class I, A | -0.0436392 |
| EGFR | epidermal growth factor receptor | -0.0421144 |
| RAI14 | retinoic acid induced 14 | -0.0420338 |
| VCAN | versican | -0.0418022 |
| PHF3 | PHD finger protein 3 | -0.0410875 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0405826 |
| DIAPH2 | diaphanous-related formin 2 | -0.0397027 |
| RND3 | Rho family GTPase 3 | -0.0391134 |
| CANX | calnexin | -0.0387733 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0366244 |
| FNIP1 | folliculin interacting protein 1 | -0.0359332 |
| NABP1 | nucleic acid binding protein 1 | -0.0357864 |
| NDRG1 | N-myc downstream regulated 1 | -0.0353371 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0346975 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0344781 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.03417 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0331246 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0330613 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0327948 |
| NAV1 | neuron navigator 1 | -0.0324497 |
| ATXN1 | ataxin 1 | -0.0323449 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0322771 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0321434 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0320411 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0318097 |
| PLIN2 | perilipin 2 | -0.0316713 |
| CD44 | CD44 molecule (Indian blood group) | -0.0304501 |
| TMEM132D | transmembrane protein 132D | -0.0301128 |
| CALR | calreticulin | -0.0297378 |
| VCL | vinculin | -0.0296604 |
| AK1 | adenylate kinase 1 | -0.0292317 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0291227 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0291016 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0290726 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0287461 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0287424 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0282064 |
| TRIM55 | tripartite motif containing 55 | -0.0280286 |
| HLA-E | major histocompatibility complex, class I, E | -0.0279179 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0274134 |
| SQSTM1 | sequestosome 1 | -0.0265359 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0265306 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0263297 |
| WDR27 | WD repeat domain 27 | -0.0263001 |
| EHBP1 | EH domain binding protein 1 | -0.0261003 |
| EGR1 | early growth response 1 | -0.0257437 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0255141 |
| INHBA | inhibin, beta A | -0.0254072 |
| AUTS2 | autism susceptibility candidate 2 | -0.0249546 |
| PTH2R | parathyroid hormone 2 receptor | -0.0249464 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0248563 |
| NRN1 | neuritin 1 | -0.024852 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0247764 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0242683 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0242278 |
| PALLD | palladin, cytoskeletal associated protein | -0.0241857 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0240254 |
| IER3 | immediate early response 3 | -0.0239989 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.023935 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0239264 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0238936 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0238282 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0236902 |
| TMEM263 | transmembrane protein 263 | -0.0235119 |
| GOLGB1 | golgin B1 | -0.0234126 |
