| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Penfluridol perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Penfluridol_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.180073 |
| SQSTM1 | sequestosome 1 | 0.0986281 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0974305 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.079814 |
| CENPF | centromere protein F, 350/400kDa | 0.0760499 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0708544 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0697742 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0688781 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0672929 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0625286 |
| TXNRD1 | thioredoxin reductase 1 | 0.0621955 |
| AHR | aryl hydrocarbon receptor | 0.0578144 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0567752 |
| CANX | calnexin | 0.0529415 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0512571 |
| CD109 | CD109 molecule | 0.0499071 |
| MKI67 | marker of proliferation Ki-67 | 0.0474067 |
| APP | amyloid beta (A4) precursor protein | 0.0465267 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0464694 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0451063 |
| FAM13A | family with sequence similarity 13, member A | 0.0447086 |
| SUCO | SUN domain containing ossification factor | 0.0428279 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0422435 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0419116 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0408021 |
| SPAG9 | sperm associated antigen 9 | 0.0405081 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0398219 |
| RTN4 | reticulon 4 | 0.0385686 |
| ZNF292 | zinc finger protein 292 | 0.0382407 |
| GPC6 | glypican 6 | 0.0378241 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0374428 |
| NUP58 | nucleoporin 58 | 0.0369088 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.036703 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0359603 |
| PGK1 | phosphoglycerate kinase 1 | 0.0358442 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337115 |
| QKI | QKI, KH domain containing, RNA binding | 0.0336817 |
| ANXA5 | annexin A5 | 0.0322745 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0321621 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0313189 |
| RAB8B | RAB8B, member RAS oncogene family | 0.030932 |
| ANLN | anillin, actin binding protein | 0.0307906 |
| RAB18 | RAB18, member RAS oncogene family | 0.0305781 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0302768 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0300763 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0297135 |
| CLTC | clathrin, heavy chain (Hc) | 0.0296649 |
| CDC73 | cell division cycle 73 | 0.0296213 |
| FAT1 | FAT atypical cadherin 1 | 0.0293786 |
| RNF145 | ring finger protein 145 | 0.0290537 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0290233 |
| UBC | ubiquitin C | 0.0287096 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0284996 |
| NEK7 | NIMA-related kinase 7 | 0.0284807 |
| ENO1 | enolase 1, (alpha) | 0.0282774 |
| NAV2 | neuron navigator 2 | 0.0281068 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0280027 |
| GOLGA4 | golgin A4 | 0.0279253 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0278309 |
| ECT2 | epithelial cell transforming 2 | 0.0277937 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0277774 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0274402 |
| FBXO32 | F-box protein 32 | 0.0272892 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0269453 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0268288 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0266877 |
| TMEM156 | transmembrane protein 156 | 0.0266477 |
| SNX9 | sorting nexin 9 | 0.0265705 |
| PTK2 | protein tyrosine kinase 2 | 0.0263387 |
| YAP1 | Yes-associated protein 1 | 0.0257834 |
| TPM3 | tropomyosin 3 | 0.0254496 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0253616 |
| YME1L1 | YME1-like 1 ATPase | 0.0252398 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0252388 |
| COPA | coatomer protein complex, subunit alpha | 0.0252159 |
| PLIN2 | perilipin 2 | 0.0251403 |
| RHEB | Ras homolog enriched in brain | 0.0250439 |
| INSIG1 | insulin induced gene 1 | 0.0250165 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0249502 |
| FOSL1 | FOS-like antigen 1 | 0.0247275 |
| NCKAP1 | NCK-associated protein 1 | 0.0247211 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.02469 |
| SEPTIN7 | septin 7 | 0.0246527 |
| INSIG2 | insulin induced gene 2 | 0.0242131 |
| HELZ | helicase with zinc finger | 0.0241351 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0240142 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0238752 |
| ARRDC3 | arrestin domain containing 3 | 0.0236948 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0235592 |
| DIAPH3 | diaphanous-related formin 3 | 0.0235346 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0235165 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0234631 |
| XPO1 | exportin 1 | 0.02309 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0230497 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0230485 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0229832 |
| HDGF | hepatoma-derived growth factor | 0.0229127 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0228763 |
| EZR | ezrin | 0.0228106 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0227859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.263017 |
| NRG1 | neuregulin 1 | -0.245517 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166275 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.137125 |
| HMGA2 | high mobility group AT-hook 2 | -0.114331 |
| VCL | vinculin | -0.104022 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0848904 |
| TMSB10 | thymosin beta 10 | -0.0808178 |
| EFNA5 | ephrin-A5 | -0.073728 |
| GLIS3 | GLIS family zinc finger 3 | -0.0689197 |
| MT2A | metallothionein 2A | -0.064865 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0530919 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0529392 |
| INTS6 | integrator complex subunit 6 | -0.0481664 |
| NTN4 | netrin 4 | -0.0478678 |
| PALLD | palladin, cytoskeletal associated protein | -0.0476847 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0462968 |
| AEBP2 | AE binding protein 2 | -0.0418366 |
| HLA-B | major histocompatibility complex, class I, B | -0.0411116 |
| RAI14 | retinoic acid induced 14 | -0.0408487 |
| ASPH | aspartate beta-hydroxylase | -0.0406468 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0401334 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0397072 |
| SYT1 | synaptotagmin I | -0.0388528 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0372921 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0360978 |
| FTL | ferritin, light polypeptide | -0.0356654 |
| EGR1 | early growth response 1 | -0.0338392 |
| PTMA | prothymosin, alpha | -0.0335025 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.032884 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0325917 |
| LOXL2 | lysyl oxidase-like 2 | -0.0322379 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0319667 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0317909 |
| FHL2 | four and a half LIM domains 2 | -0.031695 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0306049 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.030269 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0295595 |
| ITGA1 | integrin, alpha 1 | -0.0289839 |
| S100A6 | S100 calcium binding protein A6 | -0.0282058 |
| RASAL2 | RAS protein activator like 2 | -0.0275423 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0270201 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0269844 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.026446 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0257249 |
| NXN | nucleoredoxin | -0.025696 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0255763 |
| TNS3 | tensin 3 | -0.0255636 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0254407 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0245922 |
| NDRG1 | N-myc downstream regulated 1 | -0.0240947 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0240918 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0238101 |
| RPL37A | ribosomal protein L37a | -0.0237684 |
| KSR1 | kinase suppressor of ras 1 | -0.0237472 |
| RIGI | RNA sensor RIG-I | -0.0234134 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0230826 |
| TGFB1 | transforming growth factor, beta 1 | -0.0230218 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0229136 |
| SEPTIN9 | septin 9 | -0.0228711 |
| TUFT1 | tuftelin 1 | -0.0228124 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0227399 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0226727 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0224987 |
| OSMR | oncostatin M receptor | -0.0224898 |
| RNF213 | ring finger protein 213 | -0.022443 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0223034 |
| RPL35A | ribosomal protein L35a | -0.0221691 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0217546 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0214669 |
| PRKCA | protein kinase C, alpha | -0.0214189 |
| VCAN | versican | -0.0212163 |
| HLA-A | major histocompatibility complex, class I, A | -0.0211027 |
| NAV1 | neuron navigator 1 | -0.0208001 |
| TNNC1 | troponin C type 1 (slow) | -0.0206955 |
| RAB31 | RAB31, member RAS oncogene family | -0.0205738 |
| AOPEP | aminopeptidase O (putative) | -0.0204442 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.020348 |
| MX2 | MX dynamin-like GTPase 2 | -0.0202291 |
| TGFA | transforming growth factor, alpha | -0.0201741 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0201422 |
| ACTG1 | actin gamma 1 | -0.0199836 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0199595 |
| ECE1 | endothelin converting enzyme 1 | -0.0199196 |
| ABR | active BCR-related | -0.0196225 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0196142 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0194962 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0193679 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0190459 |
| RPS19 | ribosomal protein S19 | -0.0188149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0187619 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0187048 |
| CCDC138 | coiled-coil domain containing 138 | -0.0185406 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0184864 |
| EPN2 | epsin 2 | -0.0181241 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0181215 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0180925 |
| LRRC23 | leucine rich repeat containing 23 | -0.0180913 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0180697 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0180693 |
