| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pentamidine (isethionate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0759003 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0630492 |
| GOLGA4 | golgin A4 | 0.0338527 |
| GPC5 | glypican 5 | 0.0324361 |
| TPM3 | tropomyosin 3 | 0.0323515 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0322872 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.031037 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0286529 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0266629 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0265813 |
| RPS6 | ribosomal protein S6 | 0.0255784 |
| IRS2 | insulin receptor substrate 2 | 0.0255366 |
| ARRDC3 | arrestin domain containing 3 | 0.0253494 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0250695 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0249615 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0242343 |
| SET | SET nuclear proto-oncogene | 0.0238316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0237766 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0216965 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0216836 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0214507 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0212121 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0208973 |
| XPO1 | exportin 1 | 0.0197107 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0191789 |
| HDGF | hepatoma-derived growth factor | 0.0191447 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.019099 |
| RPS2 | ribosomal protein S2 | 0.0188684 |
| PLK2 | polo-like kinase 2 | 0.0188246 |
| CDK19 | cyclin-dependent kinase 19 | 0.0185205 |
| RPL3 | ribosomal protein L3 | 0.0183729 |
| MPZL1 | myelin protein zero-like 1 | 0.018362 |
| SP3 | Sp3 transcription factor | 0.018265 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.018029 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0179487 |
| G0S2 | G0/G1 switch 2 | 0.0179091 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0177536 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0176687 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0175934 |
| TPR | translocated promoter region, nuclear basket protein | 0.0174726 |
| RPL14 | ribosomal protein L14 | 0.0172129 |
| ZNF148 | zinc finger protein 148 | 0.0171162 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0170839 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0166361 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0165531 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0164487 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0164214 |
| METTL15 | methyltransferase like 15 | 0.0163346 |
| KLHDC10 | kelch domain containing 10 | 0.0162372 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0161382 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0160384 |
| RPS27 | ribosomal protein S27 | 0.0157946 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0157095 |
| MKRN1 | makorin ring finger protein 1 | 0.015466 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0151652 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0150971 |
| TMEM87B | transmembrane protein 87B | 0.0149346 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0148327 |
| FAM13A | family with sequence similarity 13, member A | 0.0147725 |
| PLEC | plectin | 0.0147469 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0146572 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.0145488 |
| RNF145 | ring finger protein 145 | 0.0144594 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0144486 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0144324 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0143154 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0140949 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0140777 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.013996 |
| RPL36 | ribosomal protein L36 | 0.0139312 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0139054 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0138756 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0138286 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0137371 |
| USP3 | ubiquitin specific peptidase 3 | 0.0136856 |
| NRP2 | neuropilin 2 | 0.0136078 |
| USP33 | ubiquitin specific peptidase 33 | 0.0135628 |
| VIRMA | vir like m6A methyltransferase associated | 0.0134891 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0134372 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0133549 |
| DNM2 | dynamin 2 | 0.0133104 |
| CDK13 | cyclin-dependent kinase 13 | 0.0132961 |
| TMEM41B | transmembrane protein 41B | 0.0132309 |
| ATXN2 | ataxin 2 | 0.0132009 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0131831 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0131564 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0131131 |
| GPR107 | G protein-coupled receptor 107 | 0.0129761 |
| SUCO | SUN domain containing ossification factor | 0.0129382 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.0129163 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0128787 |
| PTMA | prothymosin, alpha | 0.0128264 |
| RPS8 | ribosomal protein S8 | 0.0128049 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0126803 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0126722 |
| ANAPC5 | anaphase promoting complex subunit 5 | 0.0126656 |
| CCNY | cyclin Y | 0.0125643 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0125608 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0124738 |
| CBX3 | chromobox homolog 3 | 0.0124474 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.151234 |
| GPC6 | glypican 6 | -0.145286 |
| ASPH | aspartate beta-hydroxylase | -0.13206 |
| EXT1 | exostosin glycosyltransferase 1 | -0.120863 |
| CD44 | CD44 molecule (Indian blood group) | -0.108781 |
| FNDC3B | fibronectin type III domain containing 3B | -0.103523 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0890611 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.086612 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0831219 |
| VCL | vinculin | -0.0728592 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0710799 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0681731 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0667656 |
| GLIS3 | GLIS family zinc finger 3 | -0.066277 |
| TMSB10 | thymosin beta 10 | -0.0656988 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0642895 |
| MAP1B | microtubule-associated protein 1B | -0.0638409 |
| RAI14 | retinoic acid induced 14 | -0.0625661 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0608741 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0569951 |
| INTS6 | integrator complex subunit 6 | -0.0536661 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0535808 |
| RIGI | RNA sensor RIG-I | -0.05305 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0523648 |
| KYNU | kynureninase | -0.0520231 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0506529 |
| RNF213 | ring finger protein 213 | -0.048963 |
| PALLD | palladin, cytoskeletal associated protein | -0.0479632 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0458296 |
| FAM107B | family with sequence similarity 107, member B | -0.0452214 |
| CUX1 | cut-like homeobox 1 | -0.0445666 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0444824 |
| DGKI | diacylglycerol kinase, iota | -0.0441218 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0436397 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0431889 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0428029 |
| RND3 | Rho family GTPase 3 | -0.0418453 |
| MYO1E | myosin IE | -0.0417968 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0412685 |
| SMAD3 | SMAD family member 3 | -0.0403534 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392624 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0388683 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0384329 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0377001 |
| POTEF | POTE ankyrin domain family, member F | -0.0371951 |
| FMNL2 | formin-like 2 | -0.0362093 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0360843 |
| ACTG1 | actin gamma 1 | -0.0359853 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0353192 |
| NUP98 | nucleoporin 98kDa | -0.0346449 |
| CP | ceruloplasmin (ferroxidase) | -0.0336064 |
| SDCBP | syndecan binding protein (syntenin) | -0.0332072 |
| NABP1 | nucleic acid binding protein 1 | -0.033016 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0327622 |
| HLA-B | major histocompatibility complex, class I, B | -0.0326908 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0325879 |
| NDRG1 | N-myc downstream regulated 1 | -0.0324088 |
| SP100 | SP100 nuclear antigen | -0.0323261 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.032272 |
| RUNX1 | runt-related transcription factor 1 | -0.0322023 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318969 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.031827 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0317186 |
| JAK1 | Janus kinase 1 | -0.0315276 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0315038 |
| TPM1 | tropomyosin 1 (alpha) | -0.0312892 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0311087 |
| CALU | calumenin | -0.031004 |
| TPM4 | tropomyosin 4 | -0.0304776 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0304701 |
| UBAP2 | ubiquitin associated protein 2 | -0.0302235 |
| OSMR | oncostatin M receptor | -0.0297579 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0295764 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0294788 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0294012 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.029345 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0291375 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.028744 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0284995 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0283972 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0278087 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.027795 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0277848 |
| UBC | ubiquitin C | -0.0276951 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0276335 |
| CD82 | CD82 molecule | -0.0275974 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0273995 |
| CTSD | cathepsin D | -0.0273891 |
| SPAG9 | sperm associated antigen 9 | -0.0270607 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0270552 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0269295 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.026921 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0269169 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0268876 |
| ARF1 | ADP-ribosylation factor 1 | -0.0268086 |
| RRM2 | ribonucleotide reductase M2 | -0.0267999 |
| TMEM263 | transmembrane protein 263 | -0.0267418 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0266106 |
| FSTL1 | follistatin-like 1 | -0.0265539 |
| HLA-C | major histocompatibility complex, class I, C | -0.0264291 |
