| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.285239 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.162624 |
| VIM | vimentin | 0.152694 |
| LDHA | lactate dehydrogenase A | 0.134692 |
| B2M | beta-2-microglobulin | 0.0771591 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0744136 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0707858 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0670116 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0629766 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0557486 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0550549 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0531149 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0502304 |
| MCL1 | myeloid cell leukemia 1 | 0.0473366 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0473181 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0472854 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0472197 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0459096 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0452492 |
| RPS12 | ribosomal protein S12 | 0.0451523 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.044759 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0447122 |
| RPL37A | ribosomal protein L37a | 0.0443407 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0428661 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0420269 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0417278 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0409607 |
| ENO1 | enolase 1, (alpha) | 0.0403352 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0398043 |
| RPS17 | ribosomal protein S17 | 0.0394479 |
| RPS3 | ribosomal protein S3 | 0.0391088 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0380272 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0375748 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0364461 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0350535 |
| RPS8 | ribosomal protein S8 | 0.0340839 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0333881 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.03224 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0318647 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.031554 |
| LAMC2 | laminin, gamma 2 | 0.0313887 |
| RPL9 | ribosomal protein L9 | 0.0311724 |
| FAM107B | family with sequence similarity 107, member B | 0.030993 |
| WWOX | WW domain containing oxidoreductase | 0.0304416 |
| TMSB4X | thymosin beta 4, X-linked | 0.030368 |
| TPM3 | tropomyosin 3 | 0.0299497 |
| EZR | ezrin | 0.0298797 |
| S100A6 | S100 calcium binding protein A6 | 0.0296108 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.028796 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0282691 |
| RPL23 | ribosomal protein L23 | 0.0281722 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0279819 |
| CCDC88A | coiled-coil domain containing 88A | 0.0276375 |
| SET | SET nuclear proto-oncogene | 0.0273568 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0271434 |
| CRY1 | cryptochrome circadian clock 1 | 0.0269126 |
| RTN4 | reticulon 4 | 0.0266028 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0263133 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0262147 |
| TPI1 | triosephosphate isomerase 1 | 0.0260347 |
| RAI1 | retinoic acid induced 1 | 0.0258771 |
| PLEC | plectin | 0.0252532 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0248724 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0243986 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0237329 |
| ANGPTL4 | angiopoietin-like 4 | 0.0236238 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0236211 |
| RPL26 | ribosomal protein L26 | 0.0233211 |
| WWC1 | WW and C2 domain containing 1 | 0.0232343 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0229329 |
| RHCG | Rh family, C glycoprotein | 0.0229018 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0228899 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0228656 |
| RPL3 | ribosomal protein L3 | 0.0228485 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0224243 |
| SLC25A51 | solute carrier family 25, member 51 | 0.0224169 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0224149 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0222874 |
| RPS2 | ribosomal protein S2 | 0.0222841 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0220838 |
| CENPF | centromere protein F, 350/400kDa | 0.0219605 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.021832 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0217779 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0216983 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0213721 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0213321 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0212714 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.021101 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0207527 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0206572 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0206282 |
| TNS1 | tensin 1 | 0.0205474 |
| RPS7 | ribosomal protein S7 | 0.0203252 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0201192 |
| KYNU | kynureninase | 0.0200917 |
| DSPP | dentin sialophosphoprotein | 0.0199854 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0198043 |
| USP47 | ubiquitin specific peptidase 47 | 0.0197314 |
| CLIC4 | chloride intracellular channel 4 | 0.019717 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0195664 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175127 |
| IGF1R | insulin-like growth factor 1 receptor | -0.122627 |
| ACTG1 | actin gamma 1 | -0.121016 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.119519 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.107456 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.105496 |
| SMAD3 | SMAD family member 3 | -0.103159 |
| RPLP1 | ribosomal protein, large, P1 | -0.0911468 |
| TMSB10 | thymosin beta 10 | -0.0908936 |
| FLNB | filamin B, beta | -0.0729744 |
| FTL | ferritin, light polypeptide | -0.0678339 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0646618 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.059623 |
| EFNA5 | ephrin-A5 | -0.0595644 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0582432 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0559061 |
| FMNL2 | formin-like 2 | -0.0533849 |
| AHNAK | AHNAK nucleoprotein | -0.0473379 |
| RPL28 | ribosomal protein L28 | -0.0469245 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0466613 |
| SBF2 | SET binding factor 2 | -0.046582 |
| PDE10A | phosphodiesterase 10A | -0.0445081 |
| S100A10 | S100 calcium binding protein A10 | -0.0441099 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0440916 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0434795 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0423065 |
| ACTN4 | actinin, alpha 4 | -0.0419571 |
| TNS3 | tensin 3 | -0.0417476 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0412962 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0407131 |
| EHBP1 | EH domain binding protein 1 | -0.0390481 |
| USP3 | ubiquitin specific peptidase 3 | -0.0390461 |
| ANXA2 | annexin A2 | -0.038791 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0383277 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0374829 |
| SMYD3 | SET and MYND domain containing 3 | -0.0370015 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0369683 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.03678 |
| RIN2 | Ras and Rab interactor 2 | -0.0352628 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0351467 |
| RPL32 | ribosomal protein L32 | -0.0350973 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0350908 |
| DUSP5 | dual specificity phosphatase 5 | -0.0350725 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0348567 |
| SPAG9 | sperm associated antigen 9 | -0.0345851 |
| OGA | O-GlcNAcase | -0.0344849 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0339911 |
| RNF213 | ring finger protein 213 | -0.0339712 |
| FA2H | fatty acid 2-hydroxylase | -0.0335353 |
| USP34 | ubiquitin specific peptidase 34 | -0.0333506 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0332837 |
| KRT81 | keratin 81, type II | -0.0330032 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0326864 |
| WDR45B | WD repeat domain 45B | -0.0324294 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0321832 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.032048 |
| VMP1 | vacuole membrane protein 1 | -0.0318732 |
| RPL8 | ribosomal protein L8 | -0.0316475 |
| RPS11 | ribosomal protein S11 | -0.0315582 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0310755 |
| NAV2 | neuron navigator 2 | -0.030845 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0308114 |
| STC1 | stanniocalcin 1 | -0.0306075 |
| ZNF638 | zinc finger protein 638 | -0.0305307 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0300777 |
| OLA1 | Obg-like ATPase 1 | -0.0300193 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0299819 |
| BPTF | bromodomain PHD finger transcription factor | -0.0298187 |
| PDE8A | phosphodiesterase 8A | -0.0291274 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0290642 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0281195 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0278144 |
| IGSF11 | immunoglobulin superfamily, member 11 | -0.0276664 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0273739 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0273435 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0273069 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0269406 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0269169 |
| SSH2 | slingshot protein phosphatase 2 | -0.0268974 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0261314 |
| HELZ | helicase with zinc finger | -0.0261169 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0260118 |
| TAOK1 | TAO kinase 1 | -0.0259092 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0258961 |
| PRELID2 | PRELI domain containing 2 | -0.025633 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0255754 |
| LAMA5 | laminin, alpha 5 | -0.0255277 |
| KIAA1217 | KIAA1217 | -0.0254425 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0252732 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0252661 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0247872 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0247556 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0246603 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.024581 |
| CFDP1 | craniofacial development protein 1 | -0.0241624 |
| VRK2 | vaccinia related kinase 2 | -0.0240831 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0238045 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0236557 |
| ETNK1 | ethanolamine kinase 1 | -0.0236405 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0236231 |
