| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.158532 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.1558 |
| CADM2 | cell adhesion molecule 2 | 0.114531 |
| MGP | matrix Gla protein | 0.111813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.10045 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0809259 |
| MEOX2 | mesenchyme homeobox 2 | 0.0767513 |
| PEG10 | paternally expressed 10 | 0.0717534 |
| PHF21A | PHD finger protein 21A | 0.0689334 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0677995 |
| COL1A2 | collagen, type I, alpha 2 | 0.0676466 |
| TMSB4X | thymosin beta 4, X-linked | 0.0651987 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0637893 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0581767 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0572123 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0540512 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0518956 |
| YBX1 | Y box binding protein 1 | 0.0518455 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0492795 |
| NFIB | nuclear factor I/B | 0.0484222 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0477047 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0459473 |
| GPC6 | glypican 6 | 0.0455769 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0450662 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411741 |
| TRERF1 | transcriptional regulating factor 1 | 0.0410032 |
| RNF130 | ring finger protein 130 | 0.0408732 |
| DEK | DEK proto-oncogene | 0.0403056 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0399146 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0397279 |
| RPL5 | ribosomal protein L5 | 0.039508 |
| NBEA | neurobeachin | 0.0394039 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0377497 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0375956 |
| CUL3 | cullin 3 | 0.0374284 |
| RBM25 | RNA binding motif protein 25 | 0.0371516 |
| B2M | beta-2-microglobulin | 0.0361091 |
| NIN | ninein (GSK3B interacting protein) | 0.0354006 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0351233 |
| TOP1 | topoisomerase (DNA) I | 0.0344109 |
| QKI | QKI, KH domain containing, RNA binding | 0.0340354 |
| CALR | calreticulin | 0.0325115 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324399 |
| PLS3 | plastin 3 | 0.0324375 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0318128 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.031787 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.031442 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0312554 |
| KAZN | kazrin, periplakin interacting protein | 0.0311782 |
| SUCO | SUN domain containing ossification factor | 0.0311203 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0309062 |
| UBE3A | ubiquitin protein ligase E3A | 0.0308365 |
| DIDO1 | death inducer-obliterator 1 | 0.0307819 |
| UTRN | utrophin | 0.0305111 |
| LATS2 | large tumor suppressor kinase 2 | 0.0302707 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0301337 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0298921 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0298589 |
| JMJD1C | jumonji domain containing 1C | 0.0298445 |
| MEST | mesoderm specific transcript | 0.0295724 |
| PCM1 | pericentriolar material 1 | 0.0295321 |
| SHROOM3 | shroom family member 3 | 0.0292836 |
| PTMA | prothymosin, alpha | 0.0288488 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0288347 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0287089 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0284512 |
| SKP1 | S-phase kinase-associated protein 1 | 0.028197 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0280957 |
| MSRA | methionine sulfoxide reductase A | 0.028084 |
| RPL14 | ribosomal protein L14 | 0.0274114 |
| FAM13A | family with sequence similarity 13, member A | 0.0273778 |
| HBS1L | HBS1-like translational GTPase | 0.0273309 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0272431 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0272251 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0271744 |
| HMGA2 | high mobility group AT-hook 2 | 0.0271031 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0267597 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0266494 |
| URI1 | URI1, prefoldin-like chaperone | 0.026632 |
| ZFHX3 | zinc finger homeobox 3 | 0.0265819 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0264562 |
| TPR | translocated promoter region, nuclear basket protein | 0.0262527 |
| TRIM9 | tripartite motif containing 9 | 0.026221 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.025938 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0258385 |
| ACTN4 | actinin, alpha 4 | 0.0257938 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0253099 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.025239 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.025212 |
| SLC35E1 | solute carrier family 35, member E1 | 0.0251596 |
| INO80 | INO80 complex subunit | 0.0251538 |
| FTL | ferritin, light polypeptide | 0.0251495 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.0248217 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0246979 |
| TENM3 | teneurin transmembrane protein 3 | 0.0246949 |
| TBC1D32 | TBC1 domain family, member 32 | 0.024168 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.024135 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0240739 |
| ZNF33A | zinc finger protein 33A | 0.0237726 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0237036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.067311 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0635839 |
| RPS2 | ribosomal protein S2 | -0.0555782 |
| HMGB2 | high mobility group box 2 | -0.0539485 |
| MT2A | metallothionein 2A | -0.0511599 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0484157 |
| MKI67 | marker of proliferation Ki-67 | -0.0456009 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0452508 |
| ZNF292 | zinc finger protein 292 | -0.0450016 |
| IER3 | immediate early response 3 | -0.0438151 |
| H1-4 | H1.4 linker histone, cluster member | -0.0437329 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0411989 |
| RACK1 | receptor for activated C kinase 1 | -0.041099 |
| IGF2 | insulin-like growth factor 2 | -0.038492 |
| SBF2 | SET binding factor 2 | -0.0382986 |
| RPL35A | ribosomal protein L35a | -0.0378289 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0377158 |
| CLTC | clathrin, heavy chain (Hc) | -0.0376961 |
| CENPF | centromere protein F, 350/400kDa | -0.0371011 |
| RHEB | Ras homolog enriched in brain | -0.0370892 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0365196 |
| RPS18 | ribosomal protein S18 | -0.0356993 |
| GSE1 | Gse1 coiled-coil protein | -0.0356898 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0353039 |
| PDE10A | phosphodiesterase 10A | -0.0345376 |
| SFSWAP | splicing factor, suppressor of white-apricot family | -0.0344681 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0343192 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0342374 |
| PARD3 | par-3 family cell polarity regulator | -0.0342346 |
| RPS23 | ribosomal protein S23 | -0.0332394 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0331047 |
| RPL11 | ribosomal protein L11 | -0.0329026 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0328794 |
| HMGA1 | high mobility group AT-hook 1 | -0.0326113 |
| RPL9 | ribosomal protein L9 | -0.0325438 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0312425 |
| GLG1 | golgi glycoprotein 1 | -0.0310029 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.0308939 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0305026 |
| SFTPA2 | surfactant protein A2 | -0.0304438 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0296734 |
| TPX2 | TPX2, microtubule-associated | -0.0296022 |
| SQSTM1 | sequestosome 1 | -0.0294914 |
| SON | SON DNA binding protein | -0.0293623 |
| RPL31 | ribosomal protein L31 | -0.0292052 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0287406 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0286065 |
| CENPE | centromere protein E, 312kDa | -0.0285637 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0285092 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0283159 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0280061 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0279725 |
| FOXK2 | forkhead box K2 | -0.02754 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0275273 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0270779 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.026949 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0267854 |
| USP34 | ubiquitin specific peptidase 34 | -0.0265624 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0264153 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0263995 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0263425 |
| CDC73 | cell division cycle 73 | -0.026211 |
| DCP2 | decapping mRNA 2 | -0.0258259 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0258223 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.025437 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0251428 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0250867 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0250718 |
| SPAG9 | sperm associated antigen 9 | -0.0248843 |
| RPS27 | ribosomal protein S27 | -0.0248779 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0248525 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | -0.0247048 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0242651 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0242406 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0241019 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0240947 |
| BRD4 | bromodomain containing 4 | -0.0238281 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0237977 |
| RPS15 | ribosomal protein S15 | -0.0237476 |
| UBC | ubiquitin C | -0.0236448 |
| STX8 | syntaxin 8 | -0.0234306 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.023282 |
| H3-3B | H3.3 histone B | -0.0232691 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | -0.0232359 |
| RPL26 | ribosomal protein L26 | -0.0231375 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0230817 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0229133 |
| JMY | junction mediating and regulatory protein, p53 cofactor | -0.0228861 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0228346 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0227884 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.022768 |
| NUP98 | nucleoporin 98kDa | -0.0227085 |
| THOC2 | THO complex 2 | -0.0226953 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0226953 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0223805 |
| TLK1 | tousled-like kinase 1 | -0.0223007 |
| CCNA2 | cyclin A2 | -0.0222217 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0221759 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.0221575 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0220568 |
