| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | 0.144961 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.141893 |
| CEP250 | centrosomal protein 250kDa | 0.0947396 |
| INTS6 | integrator complex subunit 6 | 0.0715502 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0679064 |
| NDRG1 | N-myc downstream regulated 1 | 0.0669244 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0662357 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0631847 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0615378 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0614316 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0547953 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0516332 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0487627 |
| VMP1 | vacuole membrane protein 1 | 0.0457769 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0454916 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0436406 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0432211 |
| SP100 | SP100 nuclear antigen | 0.0431054 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.04246 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.04209 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.041267 |
| PTK2 | protein tyrosine kinase 2 | 0.0409184 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0407143 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0406769 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0402504 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0397721 |
| MCL1 | myeloid cell leukemia 1 | 0.0393773 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0392775 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0391638 |
| RAD51B | RAD51 paralog B | 0.0389961 |
| CLTC | clathrin, heavy chain (Hc) | 0.0379873 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0378473 |
| DTNA | dystrobrevin, alpha | 0.0366705 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0366292 |
| RBM47 | RNA binding motif protein 47 | 0.0362997 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0360364 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0360157 |
| BBX | bobby sox homolog (Drosophila) | 0.0357281 |
| VCP | valosin containing protein | 0.0355687 |
| RCOR1 | REST corepressor 1 | 0.0346267 |
| LASP1 | LIM and SH3 protein 1 | 0.0344415 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0335556 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0335069 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0330306 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0328337 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0319204 |
| DENND1A | DENN/MADD domain containing 1A | 0.0316817 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0316772 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0313178 |
| CCNY | cyclin Y | 0.0310769 |
| FAM168A | family with sequence similarity 168, member A | 0.0310489 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.030549 |
| ATXN1 | ataxin 1 | 0.0303107 |
| SBF2 | SET binding factor 2 | 0.0302475 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0301963 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.030144 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0299665 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.029965 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0296801 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0296488 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0289507 |
| CDK13 | cyclin-dependent kinase 13 | 0.0288718 |
| TMEM123 | transmembrane protein 123 | 0.0288513 |
| EGFR | epidermal growth factor receptor | 0.0288403 |
| PRELID2 | PRELI domain containing 2 | 0.0288389 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.028822 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0284285 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0284035 |
| KRT86 | keratin 86, type II | 0.0282073 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0282068 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0280389 |
| RTN3 | reticulon 3 | 0.0279869 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0278502 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0276026 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0274143 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0270592 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0268839 |
| ZNF292 | zinc finger protein 292 | 0.0268092 |
| PLSCR2 | phospholipid scramblase 2 | 0.0267718 |
| FOXO3 | forkhead box O3 | 0.0267486 |
| PARD3 | par-3 family cell polarity regulator | 0.0266235 |
| FAM219A | family with sequence similarity 219, member A | 0.0265296 |
| EFNA5 | ephrin-A5 | 0.0264484 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0260143 |
| TPD52 | tumor protein D52 | 0.0257916 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0257742 |
| ADIPOR2 | adiponectin receptor 2 | 0.0257598 |
| VEGFA | vascular endothelial growth factor A | 0.0257398 |
| AEBP2 | AE binding protein 2 | 0.0255855 |
| ACACA | acetyl-CoA carboxylase alpha | 0.02556 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0254478 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.025436 |
| AFF1 | AF4/FMR2 family, member 1 | 0.025436 |
| MSI2 | musashi RNA-binding protein 2 | 0.0253576 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0253328 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.025326 |
| JMJD1C | jumonji domain containing 1C | 0.0250447 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.024989 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0248133 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0247272 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0753853 |
| MT2A | metallothionein 2A | -0.0569295 |
| NTN4 | netrin 4 | -0.0549567 |
| S100A8 | S100 calcium binding protein A8 | -0.0511797 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0509552 |
| RPL23 | ribosomal protein L23 | -0.0505406 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0468533 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0464237 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0452453 |
| S100A9 | S100 calcium binding protein A9 | -0.0449798 |
| OSMR | oncostatin M receptor | -0.0429681 |
| PTMA | prothymosin, alpha | -0.0408442 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0343395 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0337486 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0327334 |
| KAZN | kazrin, periplakin interacting protein | -0.0308369 |
| UBC | ubiquitin C | -0.0292402 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0282706 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0281987 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0273794 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0270191 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0263579 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0262958 |
| TMSB10 | thymosin beta 10 | -0.0259221 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0243164 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0243092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0242707 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0241558 |
| SMIM14 | small integral membrane protein 14 | -0.0241294 |
| TMC5 | transmembrane channel-like 5 | -0.0239126 |
| S100A7 | S100 calcium binding protein A7 | -0.0239113 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0235441 |
| TENM2 | teneurin transmembrane protein 2 | -0.0232781 |
| S100A14 | S100 calcium binding protein A14 | -0.0231153 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0229543 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0226319 |
| KLF6 | Kruppel-like factor 6 | -0.0225588 |
| ABHD17C | abhydrolase domain containing 17C | -0.0223483 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0223336 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0218328 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0218311 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.021806 |
| INSR | insulin receptor | -0.0216695 |
| SDC4 | syndecan 4 | -0.0215439 |
| CFB | complement factor B | -0.0212967 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.020954 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0209255 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0207099 |
| AHNAK | AHNAK nucleoprotein | -0.0201925 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0201755 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0196537 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0195148 |
| CALR | calreticulin | -0.0194844 |
| S100A6 | S100 calcium binding protein A6 | -0.0192889 |
| TXNRD1 | thioredoxin reductase 1 | -0.0191651 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0190444 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.018741 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0186388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0179348 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0179014 |
| IFNGR1 | interferon gamma receptor 1 | -0.0178763 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0177057 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0174668 |
| CCNI | cyclin I | -0.017406 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0173824 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0172046 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0169842 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0169379 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0169083 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0166354 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.01656 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0164784 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0164545 |
| ANKRD30A | ankyrin repeat domain 30A | -0.016385 |
| RPS27A | ribosomal protein S27a | -0.0163637 |
| POTEF | POTE ankyrin domain family, member F | -0.0162862 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0162861 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0162412 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0162047 |
| WWOX | WW domain containing oxidoreductase | -0.0161961 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0161553 |
| GATA3 | GATA binding protein 3 | -0.0160635 |
| MIEN1 | migration and invasion enhancer 1 | -0.0160602 |
| S100P | S100 calcium binding protein P | -0.0160205 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0159949 |
| BICDL1 | BICD family like cargo adaptor 1 | -0.0158023 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0157828 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0155968 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0154338 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0151629 |
| CD9 | CD9 molecule | -0.0150783 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0149748 |
| SGMS1 | sphingomyelin synthase 1 | -0.0149614 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0147621 |
| DUSP6 | dual specificity phosphatase 6 | -0.0146028 |
| PGR | progesterone receptor | -0.0144465 |
| NRCAM | neuronal cell adhesion molecule | -0.0143835 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0142285 |
| TMEM45B | transmembrane protein 45B | -0.0141292 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0138466 |
