| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.148758 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.110308 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0863163 |
| RPS12 | ribosomal protein S12 | 0.0791283 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0755244 |
| RPS8 | ribosomal protein S8 | 0.0676226 |
| B2M | beta-2-microglobulin | 0.0662185 |
| VCL | vinculin | 0.0618339 |
| RPS17 | ribosomal protein S17 | 0.0564001 |
| SET | SET nuclear proto-oncogene | 0.0558915 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0519826 |
| NEBL | nebulette | 0.0510337 |
| RCC1 | regulator of chromosome condensation 1 | 0.0508177 |
| MLIP | muscular LMNA-interacting protein | 0.0502125 |
| RPS2 | ribosomal protein S2 | 0.050156 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0481519 |
| RPL37A | ribosomal protein L37a | 0.0479191 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0459847 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0441838 |
| TOX | thymocyte selection-associated high mobility group box | 0.041219 |
| PNN | pinin, desmosome associated protein | 0.0407903 |
| RPL9 | ribosomal protein L9 | 0.040676 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0401849 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0396614 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0394215 |
| TMEM259 | transmembrane protein 259 | 0.039302 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0391838 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.039064 |
| MAGEA4 | melanoma antigen family A4 | 0.0380717 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0377385 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0373414 |
| RPS6 | ribosomal protein S6 | 0.0372988 |
| SNX14 | sorting nexin 14 | 0.0369571 |
| TENM3 | teneurin transmembrane protein 3 | 0.0369072 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0368523 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0366659 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0357352 |
| RPS3 | ribosomal protein S3 | 0.0356298 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0352635 |
| VIM | vimentin | 0.0351772 |
| RBM25 | RNA binding motif protein 25 | 0.0350385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0346656 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0338458 |
| JMJD1C | jumonji domain containing 1C | 0.0337064 |
| CENPF | centromere protein F, 350/400kDa | 0.0336764 |
| USP34 | ubiquitin specific peptidase 34 | 0.0332561 |
| RPLP2 | ribosomal protein, large, P2 | 0.032959 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0320357 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0316642 |
| RPL37 | ribosomal protein L37 | 0.0316446 |
| AEBP2 | AE binding protein 2 | 0.0312793 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0308516 |
| RPS13 | ribosomal protein S13 | 0.0307675 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0306017 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0305998 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0305011 |
| LDHB | lactate dehydrogenase B | 0.0296203 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0289589 |
| RPS10 | ribosomal protein S10 | 0.0288685 |
| HDAC8 | histone deacetylase 8 | 0.0280186 |
| MCL1 | myeloid cell leukemia 1 | 0.0276491 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0274487 |
| CALD1 | caldesmon 1 | 0.0269392 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266871 |
| MSH4 | mutS homolog 4 | 0.025886 |
| INTS6 | integrator complex subunit 6 | 0.025054 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0249778 |
| CDH18 | cadherin 18, type 2 | 0.0249412 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0247821 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0247692 |
| HDGF | hepatoma-derived growth factor | 0.0244812 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.024417 |
| PHF3 | PHD finger protein 3 | 0.0243047 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0241994 |
| MRNIP | MRN complex interacting protein | 0.0240688 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0239822 |
| RPL11 | ribosomal protein L11 | 0.0239063 |
| TUT4 | terminal uridylyl transferase 4 | 0.0238526 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0236248 |
| CDK19 | cyclin-dependent kinase 19 | 0.0235978 |
| BCL2L2-PABPN1 | BCL2L2-PABPN1 readthrough | 0.0235026 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0232845 |
| IPO9 | importin 9 | 0.0232596 |
| ARFGEF3 | ARFGEF family member 3 | 0.0232036 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0229454 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0229364 |
| FNBP4 | formin binding protein 4 | 0.022905 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.022814 |
| RPL27 | ribosomal protein L27 | 0.0227174 |
| ARMH4 | armadillo like helical domain containing 4 | 0.0226957 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.022566 |
| TMEM14B | transmembrane protein 14B | 0.0223701 |
| ZNF146 | zinc finger protein 146 | 0.0222022 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.022061 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.0219487 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0218606 |
| SMAD4 | SMAD family member 4 | 0.0217576 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0216399 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0216394 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0215633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CELF2 | CUGBP, Elav-like family member 2 | -0.115679 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100338 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0962011 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0938 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.085977 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0807558 |
| ACTG1 | actin gamma 1 | -0.0688887 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0687716 |
| H1-0 | H1.0 linker histone | -0.0682356 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0646638 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0591111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0580165 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0578148 |
| CADM2 | cell adhesion molecule 2 | -0.0576223 |
| NF1 | neurofibromin 1 | -0.0553957 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0541488 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0540657 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0504789 |
| ZNF217 | zinc finger protein 217 | -0.0498063 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0467945 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0457026 |
| XPO1 | exportin 1 | -0.0442852 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0431872 |
| TUBB | tubulin, beta class I | -0.042141 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0416507 |
| HMGB1 | high mobility group box 1 | -0.0416381 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0402639 |
| GNAS | GNAS complex locus | -0.039979 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | -0.0381436 |
| SHROOM3 | shroom family member 3 | -0.037612 |
| RPLP1 | ribosomal protein, large, P1 | -0.0375799 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0374625 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0374445 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0370605 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0367576 |
| RLF | rearranged L-myc fusion | -0.0365107 |
| CDC73 | cell division cycle 73 | -0.0359528 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.035718 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0349821 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0346974 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0343984 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0342938 |
| LPIN2 | lipin 2 | -0.0341097 |
| ABI2 | abl-interactor 2 | -0.0339033 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0336861 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0336676 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0335614 |
| BSG | basigin (Ok blood group) | -0.0335011 |
| WDR45B | WD repeat domain 45B | -0.0333843 |
| HMGB2 | high mobility group box 2 | -0.032989 |
| HHIP | hedgehog interacting protein | -0.0327739 |
| HDLBP | high density lipoprotein binding protein | -0.0327644 |
| USP3 | ubiquitin specific peptidase 3 | -0.0326552 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0322546 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0321493 |
| LATS2 | large tumor suppressor kinase 2 | -0.0319749 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0318855 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0317439 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0315537 |
| RNF145 | ring finger protein 145 | -0.0314453 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0313263 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0311699 |
| LDHA | lactate dehydrogenase A | -0.0311404 |
| OLA1 | Obg-like ATPase 1 | -0.0309936 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.03034 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0300247 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0300227 |
| FNBP1L | formin binding protein 1-like | -0.0300108 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0295281 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0294427 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0289258 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0288376 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0287131 |
| PEG10 | paternally expressed 10 | -0.0286566 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0286404 |
| SPAG9 | sperm associated antigen 9 | -0.0285825 |
| XPO7 | exportin 7 | -0.0285136 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0284042 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0283564 |
| MYO9A | myosin IXA | -0.0282982 |
| PDS5A | PDS5 cohesin associated factor A | -0.0282248 |
| CANX | calnexin | -0.0281748 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0281688 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.0278138 |
| SEPTIN11 | septin 11 | -0.0278106 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0277787 |
| TLK1 | tousled-like kinase 1 | -0.0276588 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0274156 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0272492 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | -0.0270187 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0270022 |
| ZNF638 | zinc finger protein 638 | -0.0269993 |
| CARD18 | caspase recruitment domain family, member 18 | -0.026957 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.026913 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0267426 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0267279 |
| FMNL2 | formin-like 2 | -0.0266177 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0266042 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0265747 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0263696 |
