| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pentamidine (isethionate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pentamidine (isethionate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.11651 |
| PHF21A | PHD finger protein 21A | 0.0892178 |
| NDRG1 | N-myc downstream regulated 1 | 0.0838852 |
| NLGN1 | neuroligin 1 | 0.0838339 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0788914 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0772642 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0743791 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0719417 |
| CD109 | CD109 molecule | 0.0687177 |
| CENPF | centromere protein F, 350/400kDa | 0.0655879 |
| PTK2 | protein tyrosine kinase 2 | 0.0649892 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0626048 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0582621 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0580836 |
| GPC6 | glypican 6 | 0.058079 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0579051 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.054828 |
| MT2A | metallothionein 2A | 0.0544607 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0509264 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0494557 |
| PRELID2 | PRELI domain containing 2 | 0.0489747 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0489441 |
| CTTNBP2 | cortactin binding protein 2 | 0.0486712 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0475406 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0449818 |
| VGF | VGF nerve growth factor inducible | 0.042886 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0425033 |
| B2M | beta-2-microglobulin | 0.0403663 |
| ZNF638 | zinc finger protein 638 | 0.0403439 |
| SETBP1 | SET binding protein 1 | 0.0389011 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0377401 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0377131 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0376401 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0367659 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0362299 |
| NUP58 | nucleoporin 58 | 0.0356991 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0354089 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0351398 |
| ZNF292 | zinc finger protein 292 | 0.0337094 |
| FOSL1 | FOS-like antigen 1 | 0.0336217 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0319377 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0313705 |
| PCDH7 | protocadherin 7 | 0.031343 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.031128 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0306357 |
| TMEM178B | transmembrane protein 178B | 0.0295904 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0292638 |
| VEGFA | vascular endothelial growth factor A | 0.0285369 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.028265 |
| INSIG1 | insulin induced gene 1 | 0.0281351 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0277751 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0274782 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0270427 |
| RFX7 | regulatory factor X, 7 | 0.0269055 |
| CABIN1 | calcineurin binding protein 1 | 0.0256582 |
| RPS12 | ribosomal protein S12 | 0.0256548 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0250513 |
| FMNL2 | formin-like 2 | 0.0249119 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.02485 |
| ATXN1 | ataxin 1 | 0.0243178 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0241197 |
| NAV1 | neuron navigator 1 | 0.0235907 |
| MEF2A | myocyte enhancer factor 2A | 0.0233924 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0233473 |
| RNF150 | ring finger protein 150 | 0.0229965 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0225929 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0225911 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0224247 |
| UTRN | utrophin | 0.022314 |
| FLNB | filamin B, beta | 0.02225 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0218169 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0215652 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0213111 |
| ZNF704 | zinc finger protein 704 | 0.0212802 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0212316 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0212101 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0212021 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0211361 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0211303 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0210353 |
| RCOR1 | REST corepressor 1 | 0.0208835 |
| CTBP2 | C-terminal binding protein 2 | 0.0207295 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.020656 |
| CCDC200 | coiled-coil domain containing 200 | 0.0203828 |
| PARVB | parvin, beta | 0.02032 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0202956 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0202689 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0201844 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0199283 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0198791 |
| SUCO | SUN domain containing ossification factor | 0.0198637 |
| RNF145 | ring finger protein 145 | 0.0198101 |
| PLIN2 | perilipin 2 | 0.0197263 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0196248 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0195408 |
| INTS6 | integrator complex subunit 6 | 0.0194362 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0193896 |
| KDM2B | lysine (K)-specific demethylase 2B | 0.0193891 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0191602 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0190487 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.386905 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192501 |
| FMN1 | formin 1 | -0.175062 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.125786 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.10889 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0818956 |
| ACTG1 | actin gamma 1 | -0.0733157 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0653796 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0638839 |
| TNNC1 | troponin C type 1 (slow) | -0.0614798 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0600788 |
| CALU | calumenin | -0.0598381 |
| HMCN1 | hemicentin 1 | -0.0562701 |
| UBC | ubiquitin C | -0.0511117 |
| VCL | vinculin | -0.0473563 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.045088 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0436726 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0424127 |
| FRMD5 | FERM domain containing 5 | -0.0403987 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0393005 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0387726 |
| MITF | microphthalmia-associated transcription factor | -0.038034 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0379311 |
| PTCHD4 | patched domain containing 4 | -0.0378565 |
| VIM | vimentin | -0.0377591 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0359168 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0356532 |
| A2M | alpha-2-macroglobulin | -0.0339429 |
| AHNAK | AHNAK nucleoprotein | -0.0335175 |
| PI15 | peptidase inhibitor 15 | -0.0332447 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0330102 |
| EHBP1 | EH domain binding protein 1 | -0.0324957 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0321344 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.032031 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0314794 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0296298 |
| ATF6 | activating transcription factor 6 | -0.0284808 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0284558 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0283025 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0277214 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.027512 |
| RHOJ | ras homolog family member J | -0.0268807 |
| DSTYK | dual serine/threonine and tyrosine protein kinase | -0.0267603 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0265356 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0263653 |
| FRMD4A | FERM domain containing 4A | -0.0260346 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0258422 |
| OXR1 | oxidation resistance 1 | -0.0253577 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0253175 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0245693 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0241629 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0241023 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0238356 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0235762 |
| CDH19 | cadherin 19, type 2 | -0.0233626 |
| APP | amyloid beta (A4) precursor protein | -0.0231368 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0230361 |
| RTN4 | reticulon 4 | -0.0229802 |
| C10ORF90 | chromosome 10 open reading frame 90 | -0.0229624 |
| PDE10A | phosphodiesterase 10A | -0.0224366 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0223875 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0223505 |
| DUSP6 | dual specificity phosphatase 6 | -0.0223396 |
| EGR1 | early growth response 1 | -0.0221681 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0221084 |
| FHL2 | four and a half LIM domains 2 | -0.0218924 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0218483 |
| SFTPA2 | surfactant protein A2 | -0.0216181 |
| POTEF | POTE ankyrin domain family, member F | -0.021291 |
| UBE3C | ubiquitin protein ligase E3C | -0.021279 |
| SDCBP | syndecan binding protein (syntenin) | -0.0209411 |
| TMEM87A | transmembrane protein 87A | -0.0204435 |
| DMD | dystrophin | -0.0202368 |
| PNLIPRP3 | pancreatic lipase-related protein 3 | -0.0200061 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0198535 |
| TCF12 | transcription factor 12 | -0.0198416 |
| RCAN1 | regulator of calcineurin 1 | -0.0198212 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0196552 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0195852 |
| HDAC9 | histone deacetylase 9 | -0.0195527 |
| HLA-E | major histocompatibility complex, class I, E | -0.0193689 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0192264 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0190112 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0188585 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0187616 |
| KLHDC10 | kelch domain containing 10 | -0.0187159 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0184548 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0183904 |
| RUNX1 | runt-related transcription factor 1 | -0.0183319 |
| AOPEP | aminopeptidase O (putative) | -0.0182632 |
| EXOC6B | exocyst complex component 6B | -0.0181719 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0181369 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0180521 |
| NPR2 | natriuretic peptide receptor 2 | -0.0179791 |
| IER3 | immediate early response 3 | -0.0179735 |
| TXNIP | thioredoxin interacting protein | -0.017957 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0179345 |
| FAM3C | family with sequence similarity 3, member C | -0.0178215 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0176949 |
| ACTN1 | actinin, alpha 1 | -0.0176301 |
